All Posts: cancer
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Biological Pathways Found That Drive Genomic Changes and Bone Metastasis in Ewing Sarcoma, a Rare Childhood Cancer
WASHINGTON (April 28, 2022) — In studies using mice grafted with human Ewing sarcoma tissue, researchers from Georgetown University Medical Center and colleagues have identified a biological pathway that is activated when tissue is starved of oxygen due to rapid growth of a tumor, thereby allowing cancer cells to make genetic changes so they can […]
Category: News Release
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New Factors That Can Predict Breast Cancer Recurrence Defined
Discovery Has the Potential to Also Benefit Treatment Choices. WASHINGTON (April 22, 2022) — Genetics and other factors that can determine if a woman is at risk for a recurrence of breast cancer have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing new research avenues for preventing a new tumor from developing. […]
Category: News Release
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Trial Stopped Early: Giving Immunotherapy Before Targeted Rx Improves Survival in Advanced Melanoma
WASHINGTON (November 15, 2021) — More people with advanced melanoma survive for two years or more when they receive a combination of two immunotherapy drugs given before a combination of two targeted therapies, if needed, compared to people who start treatment with targeted therapies. The finding comes from a clinical trial that was stopped early […]
Category: News Release
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Experimental Drug Boosts Immunotherapy Effectiveness in Pancreatic Cancer in Mice
WASHINGTON (November 4, 2021) — An experimental drug enhanced the benefit of an immunotherapy to fight pancreatic cancer in mice by increasing the number of immune cells in the immediate vicinity of the tumor, leading to a reduction in tumor growth, and in some mice, eliminating their cancer. The findings, from researchers at Georgetown Lombardi […]
Category: News Release
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Starting Mammography at Age 40 Would Reduce Disparities in Deaths for Black Women
WASHINGTON (October 18, 2021) — If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later, according to analyses conducted by a modeling team that is part of the Cancer Intervention and Surveillance Modeling Network (CISNET), funded […]
Category: News Release
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DNA Tags Enable Blood-Based Tests to Assess Cancer Treatment Outcomes
WASHINGTON (July 27, 2021) — Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s, but with rapid advances in genomics and computational analytics in just the past few years, researchers at Georgetown Lombardi Comprehensive Cancer Center now believe that studying tags, or modifications to this type of DNA, may lead to […]
Category: News Release
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Small Numbers of Cells in a Tumor Could Be Key Enablers of Cancer Metastasis
WASHINGTON (June 16, 2021) — Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists. Working with their research collaborators, the scientists found that “enabler cells” comprise about 20 […]
Category: News Release
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Clinical Trial Result Leads to New Treatment Option for Hard-to-Treat Breast Cancer
(June 4, 2021) — A clinical trial exploring a new treatment for breast cancer found that women with a hard-to-treat form of the disease lived longer without the disease coming back following treatment. The trial was conducted at sites around the world, including Georgetown Lombardi Comprehensive Cancer Center. “This finding represents a significant step forward […]
Category: Lombardi Stories
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From Husband and Wife to Caregiver and Patient, John and Liza Marshall Reflect on Their Personal Cancer Journey in New Memoir
(April 15, 2021) — As the current chief of the Division of Hematology/Oncology at Georgetown Lombardi and the director of The Ruesch Center for the Cure of Gastrointestinal Cancers, John Marshall, MD, said that the hardest yet most important job of his life was taking on the role of caregiver when his wife Liza was […]
Category: Lombardi Stories
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Renowned Georgetown Cancer and Aging Researcher Receives Top Honor in Her Field
(March 28, 2021) — When Jeanne Mandelblatt, MD, PhD, MPH, reflects on the arc of her research career, she sees no single standout moment that cemented her path. Instead, the revered member of Georgetown Lombardi Comprehensive Cancer Center and professor of oncology and medicine at Georgetown attributes her distinguished career to a continuum of work […]
Category: Special Stories