All Posts: cancer
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Types of Bacteria Vary Widely in Tumors of People with Early vs. Late-Onset Colorectal Cancer
Researchers at Georgetown University’s Lombardi Comprehensive Cancer Center studied the microbiome of people with colorectal cancer and found the makeup of the bacteria, fungi and viruses in a person’s tumor varied significantly depending on whether they were diagnosed with early onset disease (age 45 or younger) or late-onset disease (age 65 or older).
Category: News Release
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New Study Finds Personalized mRNA Vaccine Given with Immunotherapy Reduces Recurrence in High-Risk Melanoma Patients
A new study conducted by an international team of researchers, including clinical investigators at Georgetown University’s Lombardi Comprehensive Cancer Center, demonstrates that a personalized cancer mRNA vaccine combined with immunotherapy reduces recurrence and improves survival for people with advanced melanoma.
Category: Lombardi Stories
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Study Finds Relationship Between Inconsistent Treatment and Frailty in Black Cancer Survivors
Discrimination experienced by Black people can affect their health and increase their frailty, which can be particularly impactful for cancer survivors, according to a new study.
Category: News Release
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Key Studies Conducted at Georgetown Lombardi Lead to Better Treatment for People With Melanoma
(March 1, 2023) — Results from a pair of clinical trials published in recent months have changed the treatment landscape for people with advanced melanoma, offering a clearer path for improved survival. The studies, conducted at Georgetown University’s Lombardi Comprehensive Cancer Center and other cancer centers around the country, explored the best treatment options and […]
Category: Lombardi Stories
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Women with Elevated Breast Cancer Risk Could See Mortality Benefit from Estrogen-Blocking Drugs
WASHINGTON (Thursday, December 1, 2022) — While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce the risk of developing new breast cancers, a new computer modeling study led by researchers at Georgetown Lombardi Comprehensive Cancer Center and colleagues showed that these treatments could also reduce the risk of […]
Category: News Release
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Long-term Study Supports Link Between Inflammation and Cognitive Problems in Older Breast Cancer Survivors
Researchers followed hundreds of survivors for years to examine suspected source of worrying symptoms. LOS ANGELES (September 30, 2022) — Scientists are still trying to understand why many breast cancer survivors experience troubling cognitive problems for years after treatment. Inflammation is one possible culprit. A new long-term study of older breast cancer survivors, published today […]
Category: News Release
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Biological Pathways Found That Drive Genomic Changes and Bone Metastasis in Ewing Sarcoma, a Rare Childhood Cancer
WASHINGTON (April 28, 2022) — In studies using mice grafted with human Ewing sarcoma tissue, researchers from Georgetown University Medical Center and colleagues have identified a biological pathway that is activated when tissue is starved of oxygen due to rapid growth of a tumor, thereby allowing cancer cells to make genetic changes so they can […]
Category: News Release
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New Factors That Can Predict Breast Cancer Recurrence Defined
Discovery Has the Potential to Also Benefit Treatment Choices. WASHINGTON (April 22, 2022) — Genetics and other factors that can determine if a woman is at risk for a recurrence of breast cancer have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing new research avenues for preventing a new tumor from developing. […]
Category: News Release
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Trial Stopped Early: Giving Immunotherapy Before Targeted Rx Improves Survival in Advanced Melanoma
WASHINGTON (November 15, 2021) — More people with advanced melanoma survive for two years or more when they receive a combination of two immunotherapy drugs given before a combination of two targeted therapies, if needed, compared to people who start treatment with targeted therapies. The finding comes from a clinical trial that was stopped early […]
Category: News Release
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Experimental Drug Boosts Immunotherapy Effectiveness in Pancreatic Cancer in Mice
WASHINGTON (November 4, 2021) — An experimental drug enhanced the benefit of an immunotherapy to fight pancreatic cancer in mice by increasing the number of immune cells in the immediate vicinity of the tumor, leading to a reduction in tumor growth, and in some mice, eliminating their cancer. The findings, from researchers at Georgetown Lombardi […]
Category: News Release