Mass Spectrometry and Analytical Pharmacology Shared Resource (MSAPSR)
Faculty and Staff
Junfeng Ma, PhD, Co-Director is an Assistant Professor in the Department of Oncology, Lombardi Comprehensive Cancer Center (LCCC), Georgetown University Medical Center (GUMC). Dr. Ma has over 15 years of experience in mass spectrometry-based proteomics/peptidomics, with a special interest in developing sensitive and robust proteomics/peptidomics methods and applying them for basic and translational biomedical research. Dr. Ma is responsible for defining the scientific and financial goals of the MSAP and he works directly with LCCC and GUMC administrations to ensure their implementation. Dr. Ma is also responsible for establishing scientific collaborations, for writing of both grants and manuscripts. Moreover, Dr. Ma provides advice on the experimental design and novel applications for MSAP users and trainees.
Amrita Cheema, PhD, Co-Director and a tenured Professor in the Departments of Oncology and Biochemistry, Molecular and Cellular Biology at Georgetown University Medical Center, has managed the operations of MSAP since inception in 2006. Dr. Cheema manages all aspects of the metabolomics core including resource planning, equipment procurement and upgrades, quality control, staff supervision, and financial management. Dr. Cheema provides consultation on experimental design and data interpretation to researchers. Dr. Cheema is a member of the Metabolomics Research Group of the ABRF and is actively involved in benchmarking metabolomics protocols and procedures used in core facilities nationwide, demonstrating her commitment to maintaining the highest standards in her field.
Email: email@example.com; Phone: 202-687-2756; Fax: 2026878860
Metabolomics team members
- Shivani Bansal, PhD, Facility Manager (firstname.lastname@example.org)
- Yaoxiang Li, MS, Bioinformatics Scientist (email@example.com)
- Meth Jayatilake, MS, Staff Scientist (firstname.lastname@example.org)
- Sunil Bansal, PhD, Staff Scientist (email@example.com)
- Jeyalakshmi Kandhavelu, PhD, Staff Scientist (firstname.lastname@example.org)
Mass spectrometry imaging and PK/PD
Claire Carter, PhD, Co-Director is an Assistant Professor in the Department of Pathology, Hackensack Meridian School of Medicine. Dr. Carter possesses a rare translational background that combines expertise in analytical chemistry and biomedical training. She has over 10 years of experience in mass spectrometry and mass spectrometry imaging based techniques spanning multiple organ systems and pathologies. Dr. Carter’s research group centers on bioanalytical chemistry, with a particular focus on mass spectrometry imaging (MSI) and how this is utilized at the chemistry-biology interface to probe disease mechanisms and pharmaceutical PK/PD studies. Dr. Carter is responsible for overseeing mass spectrometry imaging and laser capture microdissection at CDI. The following website describes the research expertise of Dr. Carter: https://hmh-cdi.org/our-team/carter-research/ (new window)
Matthew Zimmerman, BS, Pharmacokinetic Program Manager has over 15 years of experience in mass spectrometry based applications in support of pharmacokinetic studies. He is focused on the application of LC-MS for quantitative and qualitative drug analysis to support pharmacokinetic-pharmacodynamics (PK-PD) and drug metabolism for preclinical drug development projects. His team also has expertise in the application of laser capture microdissection (LCM) for spatial quantification of drugs in tissues by LC-MS (LCM-LC-MS). Mr. Zimmerman manages a team of application scientists and he is responsible for the day-to-day running of the PK core. He liaises with collaborators and projects managers to assist in study design.
Ivana Peran, PhD is an Instructor in the Department of Oncology at Georgetown University Medical Center – Lombardi Comprehensive Cancer Center. Dr. Peran has over 10 years of experience in cancer research using pre-clinical mouse models to investigate the role of the tumor microenvironment in pancreatic cancer progression and response to treatment. Since 2021, Dr. Peran has managed the Hyperion Imaging Mass Cytometry resource in the MSAP, where she contributes to the development of workflows and assists in experimental design.
Full-time instrument operators provide comprehensive support for the following platforms:
Proteomics & Hyperion imaging
Mass spectrometry imaging (MSI) and Laser capture microdissection (LCM)
- Claire Carter, PhD (email@example.com)
Pharmacokinetics (PK) and pharmacodynamics (PD)
- Matthew Zimmerman, BS, Pharmacokinetic Program Manager (firstname.lastname@example.org)
Benefits and Opportunities of Working Within the Shared Resources
In addition to the many benefits offered to all Georgetown University employees, there are a number of benefits specific to staff of the Shared Resources. Shared Resource directors will work with staff to develop a plan for continuing education and training.