Histopathology and Tissue Shared Resource

Faculty and Staff

Faculty

Brent Harris, MD, PhD, Director

Dr. Harris is a tenured physician-scientist and neuropathologist who joined the GUMC faculty as an Assoc Professor of Neurology and Pathology and Director of Neuropathology in 2010. He was among the first MD/PhD students to graduate in the newly formed MD/PhD Program at Georgetown University in 1995. Following Georgetown, he headed West to do his residency and fellowship in anatomic pathology/neuropathology at Stanford University and stayed to do a post-doctoral fellowship in neurobiology where we studied glial-neuronal interactions in disease and synaptogenesis.  Dr. Harris took his first faculty position at Dartmouth Medical School where he helped establish and direct the ALS Center of DHMC. He was recruited to GUMC to fill a growing need in translational neurosciences at the Medical Center.  Dr. Harris has clinical appointments at MGUH, GWUH, and Howard Univ Hospital and serves as consultant for the Dept of Justice, DC Medical Examiner’s Office, and U Miami Brain Bank.  He serves on the editorial boards for several scientific journals and is currently the Chair of the Neuropathology Section for the Collage of American Pathologists.  Dr. Harris is an active educator and serves as Module Director and Course Director for Medical and Graduate School courses.  He is also the Director of the Georgetown Brain Bank.  He serves as Senator for the faculty Senate, Chair for the University’s Research Integrity Comm, and co-Chair for the Biospecimen Review Comm. Dr. Harris’ research interests include fluorescence guided resection of CNS tumors, neurodegeneration, and cellular senescence.  His laboratory has funding from NIH, Foundations, and philanthropic sources, and he is an active collaborator with investigators here at GUMC and other institutions.

Key Staff

Krysta Chaldekas, MS, Assistant Director – Operations & Tissue Banking

Ms. Chaldekas is a certified clinical research professional (CCRP) with a master’s degree in Systems Medicine from Georgetown University and a bachelor’s degree in Biology from University of California, Davis. Ms. Chaldekas is a Research Specialist with over 10 years’ experience initiating and coordinating clinical trials and translational research projects in Oncology and Pulmonary and Critical Care medicine. Ms. Chaldekas served as a clinical research coordinator at University of California, Davis Medical Center and as program manager for the Nontherapeutic Subject Registry Shared Resource (now the SRBSR) within the GUMC Lombardi Shared Resources. At HTSR, Ms. Chaldekas oversees the day to day operations of the Human Tissue Bank and serves as moderator of GUMC Lombardi’s Biospecimen Use Committee. She aids investigators in fulfilling their human tissue, clinicopathologic data, IRB/regulatory, and database-related research requirements. She became an Instructor in the Department of Oncology at GU in 2020.

Aaron Rozeboom, PhD, Assistant Director – Immunohistochemistry & Imaging

Aaron is a research technician with a doctorate in Cell and Molecular Biology from the University of Michigan and a post-doctoral fellowship from Georgetown University.  He has over 14 years of experience in basic research covering areas of HPA axis regulation, animal behavior, and molecular neuroscience.  Aaron currently directs two HTSR subgroups. One that performs the multiplex IHC staining plus multispectral imaging and analysis and the immunohistochemistry subgroup that performs general chromogenic staining. Aaron is available for consultation on any project requiring multiplex IHC, multispectral imaging and automated quantitative pathology services.

Anju Duttargi, MS, Assistant Director – Operations & Histology

Anju is a trained oral pathologist and has contributed in clinical research with several publications to her credit. In 2014, she graduated from the master’s program in Biochemistry & Molecular Biology from Georgetown University.  Anju has over 8+yeras of experience in preparing human translational research biospecimens, analyzing clinical outcomes data and preparing translational research materials to support the goals of personalized medicine for cancer diagnosis and treatment. She will currently provide high level oversight and support for the overall operations and daily function of the Histopathology and Tissue Shared Resource (HTSR). She became an Instructor in the Department of Oncology at GU in 2020.

Additional staff provide comprehensive support of the HTSR services.

Benefits and Opportunities of Working Within the Shared Resources

In addition to the many benefits offered to all Georgetown University employees, there are a number of benefits specific to staff of the Shared Resources. Shared Resource directors will work with staff to develop a plan for continuing education and training. Opportunities offered will depend on the workload of the shared resource and the availability of resources but the Shared Resource director will make every effort to ensure that staff receive the education and training needed to move their career along.