All Posts:cancer
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Reversing Immune Suppression in Pancreatic Cancer Could Lead to Novel Therapies
Georgetown Lombardi researchers discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells called macrophages are reprogrammed to help the tumor grow instead of engaging in their regular role of fighting the tumor. This insight from cell and mouse experiments has helped the scientists outline a potential way to reverse the process and possibly improve outcomes in pancreatic cancer.
Category: News Release
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New Understanding of How to Harness the Immune System to Fight Cancer
Georgetown University’s Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white blood cells, so that they have a superior memory, thereby making them more effective in killing cancer cells.
Category: News Release
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Method Developed to Identify Best Treatment Combinations for Glioblastoma Based on Unique Cellular Targets
Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for treating glioblastoma, a lethal brain tumor. This approach enabled them to predict more effective treatment combinations to fight the disease on an individualized basis. This laboratory and computational research effort was led by scientists at Georgetown Lombardi.
Category: News Release
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Professor Makes Strides in Pancreatic Cancer Detection and Treatment
Pancreatic cancer has the lowest survival rate of all cancers. Georgetown Lombardi member Jill Smith, MD, is working to improve the disease’s grim statistics. Over the past decade, Smith, a gastroenterologist and professor of medicine in the School of Medicine, has made discoveries in the lab that she’s working to translate to patients.
Category: Lombardi Stories
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An Overlooked Hormone Eyed as Deadly Driver of Postmenopausal Breast Cancer in Women with Obesity
A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in postmenopausal women with obesity. It also raises the possibility that treatment of these aggressive breast cancers could be improved with the addition of weight-loss drugs known as GLP-1 receptor agonists.
Category: News Release
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School of Health Student Presents Foundational Cancer Research at International Conference
School of Health student Keerthana Ramanathan (H’26) presented her team’s foundational cancer research at the 37th International Papillomavirus Conference (IPVS) in Bangkok, Thailand, in October. The IPVS is the primary international research conference for human papillomavirus (HPV).
Category: Lombardi Stories
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Ralph Lauren Center Pastoral Initiative Collaborates with Local Churches to Offer Cancer Education and Screening
Community outreach and engagement is a priority for the Ralph Lauren Center for Cancer Prevention at Georgetown University’s Lombardi Comprehensive Cancer Center, and as its pastoral initiative coordinator, Mireille Bright, PhD, MPH, connects with the leaders of local churches to offer cancer prevention education, screening and navigation services.
Category: Lombardi Stories
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Leading Cancer Research Centers Reinforce Importance of Safe and Effective Human Papillomavirus (HPV) Vaccination To Prevent Cancer
National Cancer Institute (NCI)-Designated Cancer Centers with leading national organizations and the University of Puerto Rico Comprehensive Cancer Center have released a joint statement reinforcing the importance of safe and effective human papillomavirus (HPV) vaccination to prevent cancer. Nationally, HPV vaccination coverage has stagnated and falls short of the national goals.
Category: News Release
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Clinical Study Deepens Understanding of Mesothelioma and Opens the Door to Potential Treatment Options
People with operable diffuse pleural mesothelioma may benefit from immunotherapy before and after surgery, based on results of a clinical trial exploring the sequence of treatment and the role of surgery for this difficult to treat cancer.
Category: News Release
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Rate of Rare Liver Cancer High Among Russian Nuclear Workers, Particularly Women, Study Finds
A new study of Russian nuclear workers, one of only a few to examine liver cancer in people exposed to radiation in a chronic, low-dose occupational setting, finds higher rates of bile duct cancer and hepatocellular carcinoma among the workers, as well as unusually high rates in women of angiosarcoma of the liver, a form of cancer that is extremely rare.
Category: News Release