All Posts: Cancer Cell Biology Program News
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New Publication: An 8-week exercise study to improve cancer treatment related fatigue and QOL among African American breast cancer patients undergoing radiation treatment: A pilot randomized clinical trial
New Publication by Claudine Isaacs et al. Cancer treatment related fatigue (CTRF) is one of the most debilitating side effects of adjuvant radiation therapy (RT). Several studies have found that
Category: Cancer Cell Biology Program News
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Esther Braselmann, Alvin Makohon-Moore, and Kevin Tong among 2023 ACS IRG Pilot Grant Recipients
Congratulations to the 2023 pilot project grant recipients, supported by ACS IRG and institutional matching funds: Esther Braselmann, PhD, Department of Chemistry, Georgetown University, CCB Prog
Category: Cancer Cell Biology Program News
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New Publication: Expansion of human amniotic epithelial cells using condition cell reprogramming technology
New Publication by Chris Albanese, et al. Human amniotic epithelial cells (hAECs) are non-immunogenic epithelial cells that can develop into cells of all three germline lineages. However, a refin
Category: Cancer Cell Biology Program News
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New Publication: Heavy-ion radiation-induced colitis and colorectal carcinogenesis in Il10-/- mice display co-activation of β-catenin and NF-κB signaling
New Publication by Albert J. Fornace Jr., et al. Space radiation-induced gastrointestinal (GI) cancer risk models for future interplanetary astronauts are being developed that primarily rely on q
Category: Cancer Cell Biology Program News
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New Publication: Low dose radiation upregulates Ras/p38 and NADPH oxidase in mouse colon two months after exposure
New Publication by Albert J Fornace Jr., et al. Exposure to ionizing is known to cause persistent cellular oxidative stress and NADPH oxidase (Nox) is a major source of cellular oxidant production
Category: Cancer Cell Biology Program News
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New Publication: Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression
New Publication by Robert I. Glazer, et al. One of the central challenges for cancer therapy is the identification of factors in the tumor microenvironment that increase tumor progression and imm
Category: Cancer Cell Biology Program News
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New Publication: Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer
New Publication by David J. Robbins, Nagi G. Ayad, et al. The Hedgehog signaling pathway functions in both embryonic development and adult tissue homeostasis. Importantly, its aberrant activation
Category: Cancer Cell Biology Program News
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Four Georgetown Lombardi Researchers Receive Grants from the Children’s Cancer Foundation
Four Georgetown Lombardi researchers were among those receiving grants for their pediatric cancer research from the Children’s Cancer Foundation at the organization’s 38th Annual Gala, held November
Category: Cancer Cell Biology Program News
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New Publication: Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib
New Publication by Craig Kessler, et al. Spleen tyrosine kinase (SYK) is an important regulatory molecule of signal transduction pathways involved in the pathogenesis of autoimmune diseases such
Category: Cancer Cell Biology Program News
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New Publication: A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth
New Publication by David J. Robbins, Nagi G. Ayad, et al. Dysregulation of Sonic hedgehog (SHH) signaling drives the growth of distinct cancer subtypes, including medulloblastoma (MB). Such cance
Category: Cancer Cell Biology Program News