New Publication: Low dose radiation upregulates Ras/p38 and NADPH oxidase in mouse colon two months after exposure

Posted in Cancer Cell Biology Program News

New Publication by Albert J Fornace Jr., et al.

Exposure to ionizing is known to cause persistent cellular oxidative stress and NADPH oxidase (Nox) is a major source of cellular oxidant production. Chronic oxidative stress is associated with a myriad of human diseases including gastrointestinal cancer. However, the roles of NADPH oxidase in relation of long-term oxidative stress in colonic epithelial cells after radiation exposure are yet to be clearly established.

Molecular Biology Reports volume 50, pages2067–2076 (2023)