Proteomics Shared Resource – About Us

The mission of Georgetown University proteomics core is to accelerate discovery by giving investigators access to cutting edge technologies in mass spectrometry-based proteomics. By using advanced mass spectrometers and well-established proteomics technologies, we are devoted to help researchers to answer questions in basic, translational and clinical biomedical research. 

Committed to providing researchers with high-quality, cost-effective services and support, we offer free consultation to each specific project, small- or large-scale, to ensure that expectations are properly managed and fulfilled. To keep scientists in our community competitive, new technologies will be incorporated into the facility as soon as possible to meet their needs. The facility is open to all investigators in and outside Georgetown University.

The high speed, sensitivity, and accuracy of our mass spectrometers allow accurate qualitative and quantitative measurements.

The most common experiments include:

1. Hypothesis-driven discovery proteomic studies of biological systems for the identification of peptides, proteins and post-translational modifications as well as their quantification by incorporating various strategies (e.g., iTRAQ-based stable isotopic labeling and label-free data independent quantification (including SWATH)
2. Targeted proteomics by mainly using multiple reaction monitoring (MRM) and parallel reaction monitoring (PRM)