The Cancer Center Support Grant (CCSG) Developmental Funds Award (DFA) is funded through Georgetown Lombardi’s CCSG, which is in turn funded by the NIH. The purpose of the award is to encourage the initiation of promising new cancer-related projects leading to peer-reviewed funding and/or high-impact publications.
Developmental funds support basic, translational, clinical, and population science research as well as the Center’s Community Outreach and Engagement (COE) and Cancer Research Training and Education Coordination (CRTEC) activities by providing opportunities to investigate innovative research with an emphasis on strategic priorities for multi-PI collaboration across the Georgetown Lombardi Comprehensive Cancer Center consortium.
The grant is a one-year award of $10,000 to $50,000 and is not renewable. Developmental funds are available to all LCCC members with a cancer relevant research focus, including basic, clinical, translational, or population sciences with the exception that investigators who have received developmental funds twice within the last five years will not be eligible for additional funds.
Projects should aim to achieve Cancer Center strategic objectives and focus on one or more of the following areas of research:
Cancer-related health disparities and issues within the LCCC catchment area and/or underrepresented minorities
Cancer and aging
Survivorship research
Correlative science associated with an investigator-initiated clinical trial derived from cancer center science
Global oncology
Advancement of a target/biomarker along the translational pipeline (from bench to bedside or vice versa)
John Casey, PhD, Ruth He, MD, PhD, and Xuefeng Liu, MD Long-Term Culture of Human Hepatocytes for Viral Hepatitis Research
Chris Loffredo, PhD, Kirti Shetty, MD, and Brent Korba, PhD HCV Mutations and Risk of Subsequent Liver Cancer in Patients with Chronic Liver Disease
Jeanne Mandelblatt, MD, PhD, and John Van Meter, PhD Neuroimaging of Cognitive Changes in Older Breast Cancer Patients
Ronit Yarden, PhD, and Michael Johnson, PhD The Role of BRCA1 Ubiquitin E3 Ligase Novel Function in Chemoresistance
Johanna Kitlinska, PhD Cortisol, Neuronal Differentiation and Neuroblastoma Development: Is There a Link?
2010/2011
Aykut Uren, MD Development of Small Molecule Inhibitors for ERG and ETV1 Transcriptive Factors
John Deeken, MD, Kristi Graves, PhD, Arnold Potosky, MHS, PhD Personalized Medicine through Pharmacogenetics in Treatment of Gastrointestinal Cancer
Ryan McAllister, PhD Primary Cells in 3D Biomechanics Assay: Motility, Force Generation, and Proteolysis
Anna Riegel, PhD Development of New Models of Early Stage Breast Cancer
Rabindra Roy, PhD, and Siva Dakshanamurthy, PhD Inhibitors of Human-N-Methylpurine-CNA Glycosylase and Chemosensitization of Glioblastomas
Yun-Ling Zheng, PhD, MPH, and Xuefeng Liu, MD Role of Non-Telomeric and Telomeric Activities of Telomerase in Cell Immortilization and Malignant Transformation
2009/2010
Christopher Albanese, PhD, Aykut Üren, MD, Milton L. Brown, Md, PhD, Jeffrey Toretsky, MD, & Bahram Moasser, PhD Effects of Arsenic Trioxide or VMY-1-103, a GUMC CDK Inhibitor, on Medulloblastoma Proliferation and Apoptosis In Vitro and In Vivo
Yali Kong, PhD & Brent Korba, PhD Development of Small Molecule Inhibitors for Hepatitis C Virus
Mary Beth Martin, PhD, Jennifer Eng-Wong, MD, & Celia Byrne, PhD Role of Metalloestrogens in Breast Cancer
2008/2009
Robert Glazer, PhD, Stephen ByersPhD, & M. Blair Marshall, MD Tumor Stem Cell Signaling in Primary Non-Small Cell Lung Cancer (NSCLC)
Ian Gallicano, PhD, Partha Banerjee, PhD, & Christopher Albanese, PhD Narrowing the Definition of the Prostate Cancer Stem Cell
Celia Byrne, PhD, & Bassem Haddad, MD Role of NOS in Breast Cancer: A Feasibility Study
2006/2007
Yun-Ling Zheng, PhD Telomere Dysfunction and Breast Cancer Risk
2005/2006
Christopher Albanese, PhD Development of Negative and Positive MR Contrast Agent for Cancer Imaging
Radoslav Goldman, PhD Isotope Dilution of Peptides for Early Detection of Liver Cancer
Offie Soldin, PhD, MBA Urban Environmental Pesticides and Childhood Cancer
Aykut Üren, MD Peptide Inhibitors of Ewing Sarcoma Oncoprotein EWS/FLI1
2004/2005
Kevin FitzGerald, PhD Functional Characterization of MLL2, a Novel Trithorax Protein
Peter Lebowitz, MD, PhD Role of PTEN-Regulated Pathways in Breast Cancer Chemosensitivity and Prognosis
Andrew Quong, PhD Microcantilever-Based Assays of Protein Expression in Breast Cancer
Offie Soldin, PhD, MBA Urban Environmental Pesticides and Childhood Cancer
Yun-Ling Zheng, PhD Telomere Dysfunction and Breast Cancer Risk
How to Apply
Information is circulated annually to Georgetown Lombardi members about how to apply to the CCSG Development Funds Awards (DFA).
