All Posts: Cancer Cell Biology Program News
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New Publication: Countermeasure development against space radiation-induced gastrointestinal carcinogenesis: Current and future perspectives
New Publication by Albert J. Fornace Jr., et al. A significantly higher probability of space radiation-induced gastrointestinal (GI) cancer incidence and mortality after a Mars mission has been p
Category: Cancer Cell Biology Program News
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New Georgetown Study Will Investigate Nanoplastics on Animal Health and Development
Chris Albanese, et al. Georgetown’s physics, chemistry and oncology departments, as well as the Lombardi Comprehensive Cancer Center’s shared zebrafish resource, are in the preliminary stages of
Category: Cancer Cell Biology Program News
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New Publication: A confirmatory basket design considering non-inferiority and superiority testing
New Publication by Robert A. Beckman, et al. For multiple rare diseases as defined by a common biomarker signature, or a disease with multiple disease subtypes of low frequency, it is often possi
Category: Cancer Cell Biology Program News
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New Publication: Stromal Senescence following Treatment with the CDK4/6 Inhibitor Palbociclib Alters the Lung Metastatic Niche and Increases Metastasis of Drug-Resistant Mammary Cancer Cells
New Publication: Anna T. Riegel, et al. CDK4/6 inhibitors (CDKis) are a first-line treatment for metastatic hormone-receptor-positive breast cancer, but resistance frequently develops. One potenti
Category: Cancer Cell Biology Program News
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Colorectal Cancer in Young People
John L. Marshall, et al. featured in CancerToday Magazine. While colorectal cancer incidence has gone down among older people, incidence rates have steadily increased for people under age 50. Youn
Category: Cancer Cell Biology Program News
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New Publication: Post-CDK 4/6 Inhibitor Therapy: Current Agents and Novel Targets
New Publication by Sandra Swain, et al. CDK4/6 inhibitors (CDK4/6i) with endocrine therapy are the established first-line treatment for metastatic and advanced hormone receptor-positive breast can
Category: Cancer Cell Biology Program News
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New Publication: Propagated Circulating Tumor Cells Uncover the Potential Role of NFκB, EMT, and TGFβ Signaling Pathways and COP1 in Metastasis
New publication by Seema Agarwal, John L. Marshall, Marcus S. Noel, Richard Schlegel, et al. Metastasis is the primary cause of cancer-related deaths, but is poorly understood. Circulating tumor c
Category: Cancer Cell Biology Program News
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New Publication: POU2AF3-rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2
New Publication by Sosipatros A. Boikos, et al. Gene fusions involving EWSR1 or FUS as the 5′ partner have been reported in a diverse array of sarcomas. Here, we characterize the histopathology an
Category: Cancer Cell Biology Program News
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New Publication: Radiotherapy Induces Innate Immune Responses in Patients Treated for Prostate Cancers
New Publication by Anatoly Dritschilo et al. As a curative or palliative treatment modality, more than 50% of patients with cancer receive radiotherapy during the course of their disease. Althoug
Category: Cancer Cell Biology Program News
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New Publication: DPYD Testing: Time to Put Patient Safety First
New Publication by Sandra Swain, et al. We recommend that pretreatment DPYD variant testing should be incorporated immediately into the standard of care for fluoropyrimidine regimens. Since fluor
Category: Cancer Cell Biology Program News