New Publication: Radiotherapy Induces Innate Immune Responses in Patients Treated for Prostate Cancers 

Posted in Cancer Cell Biology Program News

New Publication by Anatoly Dritschilo et al.

As a curative or palliative treatment modality, more than 50% of patients with cancer receive radiotherapy during the course of their disease. Although recent studies provide credence to the immune system’s role in modulating tumor response to radiotherapy, this, however, remains an understudied area in radiation oncology research. Herein, we show that molecular interactions and cellular cross-talk underlying immune responses and DNA damage response activation by radiotherapy define, at least in part, the underlying biologic basis of tumor response to radiotherapy. Validation of this concept can be used for the improvement of therapeutic strategies in radiotherapy-based cancer treatment.