Nontherapeutic Subject Registry (NTSR), under the direction of Claudine Isaacs, MD and Beth Peshkin, MS, CGC, provides centralized patient recruitment services for nontherapeutic human trials. The NTSR implements a universal protocol and consent which includes collection of core data elements from patients at GUMC with and without cancer. Patients are also consented for collection of biospecimens and tissue, and for future contact for enrollment into specific studies and follow-up. The NTSR also provides services to investigators including data entry and programming, medical record abstraction, and risk assessment counseling. The NTSR works closely with Tissue Culture Shared Resource (TCSR) and Histopathology and Tissue Shared Resource (HTSR) to provide investigators with access to patients and data that can be linked to biospecimen samples as well as tumor and non-tumor tissue.
The NTSR also encompasses the Familial Cancer Registry (FCR), which is an integrated and comprehensive resource of individuals at high genetic risk for cancer and includes detailed demographic data, family history information, medical history, cancer risk factors, tissue from surgeries (benign and malignant), tissue micro-array, and biospecimen, all of which can be linked securely and confidentially to results of genetic testing. The majority of participants are members of high-risk breast and ovarian cancer families. Participants are contacted annually to obtain updated personal and family history.
Information on services provided, language for grant proposals and IRB protocols available here. Additional information including language for IRB and grant proposal, please see the NTSR intranet page.
For more NTSR information, please contact Erin Carney at Erin.Carney@georgetown.edu or (202) 687-2219.
Co-Director: Claudine Isaacs MD
Telephone: (202) 444-0759
Lombardi Building, Podium B
Co-Director: Beth Peshkin, MS, CGC
Telephone: (202) 687-2716
Harris Building, Suite 4100
Manager: Erin Carney
Telephone: (202) 687-
Lombardi Building, LL 107
We provide lectures to TBIO 546, the Resources for Cancer Research survey course provided to all Tumor Biology Students. If you need a lecture for your course, or a one-time lecture for your research group or lab, please contact Erin Carney at Erin Carney@georgetown.edu or 202-687-2219
Tutorial and Best Practices for Protocol and Consent Development
Beth Peshkin and Elizabeth Poggi meet with investigators to review protocol language, review institutional review board (IRB) requirements, standard of care in handling genetic testing results, as well as ethical concerns regarding human subjects research.
In all publications that include data derived or methods used from Nontherapeutic Subject Registry Shared Resource, please acknowledge our resource. The Nontherapeutic Subject Registry Shared Resource is partially supported by NIH/NCI grant P30 CA051008.