The Centers for Cancer Systems Biology (CCSB) U54 Award is designed to support pilot research programs in areas relevant to the goals of Georgetown Lombardi's CCSB.

The grant is available to all faculty members and is not limited to junior faculty. The CCSB Award provides funding for Georgetown University researchers. Each of the awards is for one year only, and is not renewable. Priority will be given to projects that have a high likelihood for future funding.

Past Awardees

The Center for Cancer Systems Biology (CCSB) was established in May 2010 as a result of a $7.5 million grant from the National Cancer Institute's Integrative Cancer Biology Program. Robert Clarke, PhD, DSc, serves as the Principle Investigator working with collaborators from Virginia Tech and Fox Chase Cancer Center.

2010/2011 marks the first year that the CCSB U54 Awards have been available to Georgetown University researchers.


  • Mary Beth Martin, PhD – Role of Calcium in Hormone-Resistant Breast Cancer
  • Ronit Yarden, PhD – Dissecting the BRCA1 E3 Ubiquitin Ligase Network in Maintenance of Genomic Stability
How to Apply 

The Centers for Cancer Systems Biology (CCSB) U54 awards are designed to support pilot research programs in areas relevant to the goals of Georgetown Lombardi's CCSB. Awardees demonstrated innovative systems biology approaches to translational research and treatment of breast cancer.

All projects will be peer-reviewed and based on the following criteria:

  1. Scientific merit
  2. Technical soundness
  3. Innovation
  4. Focus on Cancer Systems Biology - does not need to be focused on breast cancer but alignment with the goals of tthe CCSB will be considered in funding prioritization
  5. Collaboration with other CCSB components
  6. Experience of the investigators - qualified new investigators per NIH criteria will receive priority if their appication has appropriate scientific merit but the award is open to all faculty members
  7. Appropriateness of the budget. Core A will provide the administrative support for this program

General rules, requirements and application can be found on LombardiNet*.

*University NetID and password required.