Histopathology and Tissue Shared Resource

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Human Tissue Bank (HTB)

Contact Angela M. Dixon, (202) 687-4815 or amd273@georgetown.edu.

1. Tissue Collection — Fresh Frozen Tissues

  • Consent from Georgetown University Hospital patients are obtained for the collection of excess tissues.
  • Fresh human tissues are collected, frozen, stored, and inventoried from various anatomic sites.
    • Brain
    • Breast
    • Colon
    • Esophagus
    • Kidney
    • Liver
    • Lung
    • Pancreas
    • Stomach
    • Thyroid
    • Uterus
  • Requests for frozen specimens must go through a specific approval process by the Tissue Review Committee. The review is based on scientific merit and statistical validity of the proposed project, amongst other factors.

 

2. Tissue Collection — GUH Archival Paraffin Embedded Tissues

  • Paraffin embedded human tissue blocks are available from the archives of the Pathology Department of the Georgetown University Hospital.
  • HTB conducts database searches of pathology records, as requested, for retrieval of human tissue blocks. Patient confidentiality is maintained in accordance with HIPAA regulations.
  • Sectioning of archival blocks is conducted in the Histology Laboratory.
  • All protocols requiring human material must have IRB approval and must adhere to HIPAA guidelines. HTB maintains an annually renewable IRB approval allowing for LCCC investigators to use the archived patient material in a de-identified fashion.
  • Permission for tissue retrieval can be granted to investigators after a one-time short application process.
  • All investigators complete a HTB Repository Use Form to utilize HTSR services.

 

3. Indivumed

  • Indivumed is headquartered in Hamburg Germany and has a partnership with Lombardi Cancer Center to establish a state of the art biobanking protocol that provides integrated clinical and molecular database for cancer which will be used for the G-DOC development.
  • Indivumed collects both fresh and paraffin embedded tissues, with matched blood and urine specimens.
  • Of these collected specimens, a portion is available for LCCC investigators and requests for these samples will be subjected to the same peer review outlined above.

 

4. Special Collections Protocols

  • HTB also provides services for PIs who have their special projects requiring tissue procurement for their studies.
  • HTB adheres to the collection procedures provided by the investigators.

 

5. Pathology Consultation.

Dr. Kallakury is available to review slides with investigators on an individual basis. Appointments can be made via email (kallakub@gunet.georgetown.edu)

 

Tissue sectioning