Biostatistics & Bioinformatics Shared Resource

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Asatiani E, Huang WX, Wang A, Haddad B, Rodriguez E, Gelmann EP. Reduced Homeoprotein NKX3.1 expression in primary prostate cancer and intraepithelial neoplasia. Cancer Research 65(4):1164-1173, 2005.

Bouker KB, Skaar TC, Harburger D, Riggins RB, Fernandez DR, Zwart A, Wang A, Clarke R. Tumor suppressor activities of Interferon Regulatory Factor-1 in human breast cancer cells. Carcinogenesis 26:1527-1535, 2005.

Chepko G, Slack R, Carbott D, Kahn S, Stedman L, Dickson RB. Cell type population sizes and cell cycle activity are differentially altered in ducts and lobules of TGFα and c-Myc transgenic mouse mammary epithelium. Tissue and Cell 37:393-412, 2005.

Clarke R, Leonessa F, Trock B. MDR/P-glycoprotein and breast cancer: Review and meta-analysis. Semin Oncol 32 (suppl 7):9-15, 2005.

Cox LS, Cañar J, Feng S, Ford MM, Tercyak KP. Social and behavioral correlates of cigarette smoking among mid-Atlantic Latino primary care patients. Cancer Epidemiology, Biomarkers and Prevention 14:1976-1980, 2005.

Isaacs C, Slack R, Gehan E, Ballen K, Boccia R, Areman E, Hayes DF, Herscowitz H, Lippman M. A Multicenter randomized clinical trial evaluating Interleukin-2 activated hematopoietic stem cell transplantation and post-transplant IL-2 for high risk breast cancer patients. Breast Cancer Research and Treatment. 93:125-134, 2005.

Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, Calvert VS, Petricoin EF, III, Liotta L, Dadachova E, Pestell RG, Lisanti MP, Bonaldo P, Scherer PE. Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. J Clin Invest 115(5):1163-1176, 2005.

Li H, Zhang Y, Glass A, Zellweger T, Gehan E, Bubendorf L, Gelmann EP, Nevalainen MT. Activation of signal transducer and activator of Transcription-5 (Stat5) in prostate cancer predicts early recurrence. Clinical Cancer Research 11(16):5863-5868, 2005.

Marshall JL, Gulley JL, Arlen P, Beetham PK, Tsang K-Y, Slack R, Hodge JW, Doren S, Grosenbach DW, Hwang J, Fox E, Odogwu L, Park S, Panicali D, Schlom J. Phase I study of sequential vaccinations with Fowlpox-CEA(6D)-TRICOM alone and sequentially with Vaccinica-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor in patients with carcinoembryonic antigen-expressing carcinomas. Journal of Clinical Oncology 23(4):1-12, 2005.

O'Malley AS, Forrest CB, Feng S, Mandelblatt J. Disparities despite coverage: Gaps in colorectal cancer screening among Medicare beneficiaries. Archives of Internal Medicine 165:2129-2135, 2005.

Ressom H, Varghese RS, Abdel-Hamid M, Abdel-Latif Eissa S, Saha D, Goldman L, Petricoin EF, Conrads TP, Veenstra TD, Loffredo CA, Goldman R. Analysis of mass spectral serum profiles for biomarker selection. Bioinformatics 21(21):4039-4045, 2005.

Ressom H, Varghese RS, Orvisky E, Drake SK, Hortin GL, Abdel-Hamid M, Loffredo CA, Goldman R. Analysis of MALDI-TOF serum profiles for biomarker selection and sample classification. Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, La Jolla, CA, pp. 378-384, 2005.

Ressom H, Varghese RS, Saha D, Orvisky E, Goldman L, Petricoin EF, Conrads TP, Veenstra TD, Abdel-Hamid M, Loffredo CA, Goldman R. Particle swarm optimization for analysis of mass spectral serum profiles. In: Proceedings of the Genetic and Evolutionary Computation Conference, GECCO-2005, HG Beyer et al. (editors), ACM Press, New York, vol. 1, pp. 431-438, 2005.

Sanderson Cox L, Feng S, Cañar J, McGlinchey Ford M, Tercyak KP. Social and behavioral correlates of cigarette smoking among mid-Atlantic Latino primary care patients. Cancer Epidemiol Biomarkers Prev 14(8):1976-80, 2005.

Sarfaty M, Feng S. Uptake of colorectal cancer screening in an uninsured population. Preventive Medicine 41:703-706, 2005.

Singh AM, Gagnon G, Collins B, Niroomand-Rad A, McRae D, Zhang Y, Regan J, Lynch J, Dritschilo A. Combined external beam radiotherapy and Pd-103 brachytherapy boost improves biochemical failure free survival in patients with clinically localized prostate cancer: Results of a matched pair analysis. Prostate 62:54-60, 2005.

Stearns V, Slack R, Greep N, Henry-Tilman R, Osborne M, Bunnel C, Ullmer L, Gallagher A, Cullen J, Gehan E, Hayes DF, Isaacs C. Paroxetine is an effective treatment for hot flashes: Results from a prospective randomized clinical trial. Journal of Clinical Oncology 23(28):6919-6930, 2005.

El-Kafrawy SA, Abdel-Hamid M, El-Daly M, Nada O, Ismail A, Ezzat S, Abdel-Latif S, bdel-Hamid A, Shields PG, Loffredo C. P53 mutations in hepatocellular carcinoma patients in Egypt. Int J Hyg Environ Health 208(4):263-270, 2005.

Ezzat S, Abdel-Hamid M, Eissa SA, Mokhtar N, Labib NA, El-Ghorory L, Mikhail NN, Abdel-Hamid A, Hifnawy T, Strickland GT, Loffredo CA. Associations of pesticides, HCV, HBV, and hepatocellular carcinoma in Egypt. Int J Hyg Environ Health 208(5):329-339, 2005.

Espinoza LA, Valikhani M, Cossio MJ, Carr T, Jung M, Hyde J, Witten ML, Smulson ME. Altered expression of γ-synuclein and detoxification-related genes in lungs of rats exposed to JP-8. Am. J. Respir. Cell Mol. Biol. 32:192-200, 2005.

Yin Y, Russell RG, Dettin LE, Bai R, Wei ZL, Kozikowski AP, Kopelovich L, Glazer RI. Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis. Cancer Res. 65:3950-3957, 2005.

Gehan E. The future of Biostatistics in cancer research. Foundations of Clinical Cancer Research 3(1): 24-25, 2005.

Feng S, Wolfe RA, Port FK. Frailty survival model analysis of the National Diseased Kidney Transplant Dataset using Poisson variance structures. Journal of the American Statistical Association 100:728-735, 2005.

Gehan E. Some applications of Bayesian methods in cancer clinical trials. Student, 5 (3), Special Issue in Honor of Sir David Cox, 2005.

Graham J, McNeney B, Seillier-Moiseiwitsch F. Stepwise detection of recombination breakpoints in sequence alignments. Bioinformatics 21:589-595, 2005.

Liu A, Wu CQ, Yu KF, Gehan E. Supplementary analysis of probabilities at the termination of a group sequential Phase II trial. Statistics in Medicine 24:1009-1027, 2005.

Seillier-Moiseiwitsch F. Statistical analysis of two-dimensional gel patterns. In: The Proteomics Protocols Handbook, Walker JM (editor), pp. 239-258, Humana Press, Totowa, New Jersey, 2005.

Wang A, Gehan E. Gene selection for microarray classification using principal component analysis. Statistics in Medicine 24:2069-2087, 2005.

Ressom H, Natarjan P, Varghese RS, Musavi MT. Applications of fuzzy logic in genomics. Journal of Fuzzy Sets and Systems 152:125-138, 2005.

Ressom H, Natarajan P. Gene expression clustering using computational intelligence. In: Bioinformatics: New Research, Yan PV (editor), pp. 1-25, Nova Science Publishers Inc., New York, 2005.