Molecular Targets & Therapeutic Resistance Program
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Selected Publications2004
Bakin R, Jung M. Cytoplasmic Sequestration of HDAC7 from Mitochondrial and Nuclear Compartments Upon Initiation of Apoptosis. J Biol Chem 2004;279:51218-51225.
Blánquez MJ, Arenas MI, Conde I, Tirado OM, Paniagua R, Notario V. Deregulated expression of the PCPH proto-oncogene in human breast cancers. Int J Oncol 2004;25:821-830.
Broustas CG, Gokhale PC, Rahman A, Dritschilo A, Ahmad I, Kasid U. BRCC2, a novel BH3-like domain-containing protein, induces apoptosis in a caspase-dependent manner. J Biol Chem 2004;279:26780-26788.
Emfietzoglou D, Karava K, Papamichael G, Moscovitch M. Monte-Carlo calculations of radial dose and restricted-let for protons in water. Radiat Prot Dosimetry 2004;110:871-879.
Espinoza LA, Li P, Lee RY, Wang Y, Boulares AH, Clarke R, Smulson ME. Evaluation of gene expression profile of keratinocytes in response to JP-8 jet fuel. Toxicol Appl Pharmacol 2004;200:93-102.
Ha HC [Mitchell Jung]. Defective activation of transcription factors for pro-inflammatory gene expression in poly (ADP-ribose) polymerase-1 deficient glia. Proc Natl Acad Sci U S A 2004;101:5087-5092.
Han S, Espinoza LA, Liao H, Boulares AH, Smulson ME. Protection by antioxidants against toxicity and apoptosis induced by the sulfur mustard analog CEES (2-chloroethylethyl sulfide) in Jurkat T cells and normal human lymphocytes. Br J Pharmacol 2004;141:795-802.
Hernandez EM, Chan CH, Xu B, Notario V, Richert JR. Role of an Internal Ribosome Entry Site in the Translational Control of the Human Transcription Factor Sp3. Int J Oncol 2004;24:719-724.
Jung M, Zhang Y, Dimtchev A, Subramanian MR, Suthanthiran K, Dritschilo A. Interstitial gene delivery in human xenograft prostate tumors using titanium metal seeds. Mol Cancer Ther 2004;3:655-659.
Kim KM, Zhang Y, Kim BY, Jeong SJ, Lee SA, Kim GD, Dritschilo A, Jung M. The p65 subunit of nuclear factor-kappaB is a molecular target for radiation sensitization of human squamous carcinoma cells. Mol Cancer Ther 2004;3:693-698.
Kumar D, Gokhale PC, Broustas C, Chakravarty D, Ahmad I, Kasid UN. Expression of SCC-S2, an anti-apoptotic molecule, correlates with enhanced proliferation and tumorigenicity of MDA-MB435 cells. Oncogene 2004;23:612-616.
Kumar D, Sakabe I, Patel S, Zhang Y, Ahmad I, Gehan EA, Whiteside TL, Kasid U. SCC-112, a novel cell cycle-regulated molecule, exhibits reduced expression in human renal carcinomas. Gene 2004;328:187-196.
Mewani RR, Tang W, Rahman A, Dritschilo A, Ahmad I, Kasid UN, Gokhale PC. Enhanced therapeutic effects of doxorubicin and paclitaxel in combination with liposome-entrapped ends-modified raf antisense oligonucleotide against human prostate, lung and breast tumor models. Int J Oncol 2004;24:1181-1188.
Moroni M, Soldatenkov V, Zhang L, Zhang Y, Stoica G, Gehan E, Rashidi B, Singh B, Ozdemirli M, and Mueller SC. Progressive Loss of Syk and Abnormal Proliferation in Breast Cancer Cells. Cancer Res 2004;64:7346-7354.
Pei J, Zhang C, Gokhale PC, Rahman A, Dritschilo A, Ahmad I, Kasid UN. Combination with liposome-entrapped, ends-modified raf antisense oligonucleotide (LErafAON) improves the anti-tumor efficacies of cisplatin, epirubicin, mitoxantrone, docetaxel and gemcitabine. Anticancer Drugs 2004;15:243-253.
Rudin CM, Marshall JL, Huang CH, Kindler HL, Zhang C, Kumar D, Gokhale PC, Steinberg J, Wanaski S, Kasid UN, Ratain MJ. Delivery of a liposomal c-raf-1 antisense oligonucleotide by weekly bolus dosing in patients with advanced solid tumors: a phase I study. Clin Cancer Res 2004;10:7244-7251.
Ryan VT, Grimwade JE, Camara JE, Crooke E, Leonard AC. E. coli pre-replication complex assembly is regulated by dynamic interplay among Fis, IHF and DnaA. Mol Microbiol 2004;51:1347-1359.
Soldatenkov VA, Potaman V. DNA-binding properties of poly(ADP-ribose) polymerase: a target for anti-cancer therapy. Current Drug Targets 2004;5:357-365.
Spruessel A, Steimann G, Jung M, Lee SA, Carr T, Fentz AK, Spangenberg J, Zornig C, Juhl HH, David KA. Tissue ischemia time affects gene and protein expression patterns within minutes following surgical tumor excision. Biotechnologies 2004;36:1030-1037.
Zhang L, Gokhale P, Mewani R, Li B, Dritschilo A, Soldatenkov V. Prostate cancer radiosensitization by targeting poly(ADP-ribose) polymerase. Mol Ther 2004;9:S234.
Zhang L, Yoo S, Dritschilo A, Belyaev I, Soldatenkov V. Targeting Ku protein for sensitizing of breast cancer cells to DNA-damage. Int J Mol Med 2004;14:153-159.
Zhang Y, Jung M, Dritschilo A, Jung M. Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors. Radiat Res 2004;161:667-674.
