Growth Regulation of Cancer Program
Overview | Leaders | Research | Publications
Selected Publications
2005
Abaan OD, Levenson A, Khan O, Furth PA, Uren A, Toretsky JA. PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis. Oncogene 2005;24:2715-2722.
Allen J, Khwaja F, Byers S, Djakiew D. The p75NTR mediates a bifurcated signal transduction cascade through the NF kappa B and JNK pathways to inhibit cell survival. Exp Cell Res 2005;304:69-80.
Asatiani E, Gelmann EP. Targeted therapies for prostate cancer. Expert Opin Ther Targets 2005;9:283-298.
Bae I, Rih JK, Kim HJ, Kang HJ, Haddad B, Kirilyuk A, Fan S, Avantaggiati ML, Rosen EM. BRCA1 regulates gene expression for orderly mitotic progression. Cell Cycle 2005;4:1641-1666.
Berg M, DiFatta J, Hoiczyk E, Schlegel R, Ketner G. Viable adenovirus vaccine prototypes: high-level production of a papillomavirus capsid antigen from the major late transcriptional unit. Proc. Natl. Acad. Sci USA 2005;102:4590-4595.
Boeneman K, Crooke E. Chromosomal replication and the cell membrane. Curr Opin Microbiol 2005;8:143-148.
Bonifant CL, Waldman T. 'Cables' suspends cancer in mice. Cancer Biol Ther 2005;4:864-865.
Camara JE, Breier AM, Brendler T, Austin S, Cozzarelli NR, Crooke E. Hda inactivation of DnaA is the predominant mechanism preventing hyperinitiation of Escherichia coli DNA replication. EMBO Rep 2005;6:736-741.
Casey J, Cote PJ, Toshkov IA, Chu CK, Gerin JL, Hornbuckle WE, Tennant BC, Korba BE. Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks. Antimicrob Agents Chemother 2005;49:4396-4399.
Chen T, Pengetnze Y, Taylor CC. Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3. Mol Cancer Ther 2005;4:217-224.
Disbrow GL, Baege AC, Kierpiec KA, Yuan H, Centeno JA, Thibodeaux CA, Hartmann D, Schlegel R. Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo. Cancer Res 2005;65:10854-10861.
Disbrow GL, Hanover JA, Schlegel R. Endoplasmic reticulum-localized human papillomavirus type 16 E5 protein alters endosomal pH but not trans-Golgi pH. J Virol 2005;79:5839-5846.
Foshay K, Rodriguez G, Hoel B, Narayan J, Gallicano GI. JAK2/STAT3 directs cardiomyogenesis within murine embryonic stem cells in vitro. Stem Cells 2005;23:530-43.
George JA, Chen T, Taylor CC. SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells. Cancer Res 2005;65:10381-10388.
Hauet T, Yao ZX, Bose HS, Wall CT, Han Z, Li W, Hales DB, Miller WL, Culty M, Papadopoulos V. Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria. Mol Endocrinol 2005;19:540-554.
Hausmann S, Altura MA, Witmer M, Singer SM, Elmendorf HG, Shuman S. Yeast-like mRNA capping apparatus in Giardia lamblia. J Biol Chem 2005;280:12077-12086.
He Z, Feng L, Zhang X, Geng Y, Parodi DA, Suarez-Quian C, Dym M. Expression of Col1a1, Col1a2 and procollagen I in germ cells of immature and adult mouse testis. Reproduction 2005;130:333-341.
Ifon ET, Pang AL, Johnson W, Cashman K, Zimmerman S, Muralidhar S, Chan WY, Casey J, Rosenthal LJ. U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3. Cancer Cell Int 2005;5:19
Iyer RP, Padmanabhan S, Zhang G, Morrey JD, Korba BE. Nucleotide analogs as novel anti-hepatitis B virus agents. Curr Opin Pharmacol. 2005;5:520-528.
Jamin N, Neumann JM, Ostuni MA, Vu TK, Yao ZX, Murail S, Robert JC, Giatzakis C, Papadopoulos V, Lacapere JJ. Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor. Mol Endocrinol 2005;19:588-594.
Jayan GC, Casey JL. Effects of conserved RNA secondary structures on hepatitis delta virus genotype I RNA editing, replication, and virus production. J Virol 2005;79:11187-11193.
Kim BY, Cho CH, Song DK, Mun KC, Suh SI, Kim SP, Shin DH, Jang BC, Kwon TK, Cha SD, Bae I, Bae JH. Ciglitizone inhibits cell proliferation in human uterine leiomyoma via an activation of store-operated Ca2+ channel. Am J Physiol Cell Physiol2005;288:C389-395.
Jung TI, Baek WK, Suh SI, Jang BC, Song DK, Bae JH, Kwon KY, Bae JH, Cha SD, Bae I, Cho CH. Down-regulation of peroxisome proliferator-activated receptor gamma in human cervical carcinoma. Gynecol Oncol. 2005;97:365-373.
LeBaron MJ, Xie J, Rui H. Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer. Mol Cancer 2005;1;4(1):6.
LeBaron MJ, Crismon HR, Utama FE, Neilson LM, Sultan AS, Johnson KJ, Andersson EC, Rui H. Ultrahigh density microarrays of solid samples. Nat Methods 2005;2:511-513.
Lecanu L, Yao W, Piechot A, Greeson J, Tzalis D, Papadopoulos V. Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against beta-amyloid-induced toxicity. Neuropharmacology 2005;49:86-96.
Lecanu L, Wenguo Y, Xu J, Greeson J, Papadopoulos V. Local anesthetic procaine protects rat pheochromocytoma PC12 cells against beta-amyloid-induced neurotoxicity. Pharmacology 2005;74:65-78.
Li H, Zhang Y, Glass A, Zellweger T, Gehan E, Bubendorf L, Gelmann EP, Nevalainen MT. Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence. Clin Cancer Res 2005;11:5863-5868.
Li Z, Kitchen JL, Boeneman K, Anand P, Crooke E. Restoration of growth to acidic phospholipid-deficient cells by DnaA(L366K) is independent of its capacity for nucleotide binding and exchange and requires DnaA. J Biol Chem 2005;280:9796-9801.
Liu X, Yuan H, Fu B, Disbrow GL, Apolinario T, Tomaic V, Kelley ML, Baker CC, Huibregtse J, Schlegel R. The E6AP ubiquitin ligase is required for transactivation of the hTERT promoter by the human papillomavirus E6 oncoprotein. J Biol Chem 2005;280:10807-10816.
Liu Y, Yao ZX, Papadopoulos V. Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells. Mol Endocrinol 2005;19:1918-1931.
Liu Y, Yao ZX, Bendavid C, Borgmeyer C, Han Z, Cavalli LR, Chan WY, Folmer J, Zirkin BR, Haddad BR, Gallicano GI, Papadopoulos V. Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice. Mol Endocrinol 2005;19:2380-2389.
Magal SS, Jackman A, Ish-Shalom S, Botzer LE, Gonen P, Schlegel R, Sherman L. Down regulation of Bax mRNA expression and protein stability by the E6 protein of human papillomavirus 16. J. Gen. Virol. 2005;86:611-621.
Malerczyk C, Schulte AM, Czubayko F, Bellon L, Macejak D, Riegel AT, Wellstein A. Ribozyme targeting of the growth factor pleiotrophin in established tumors: a gene therapy approach. Gene Ther 2005;12:339-346.
Mani A, Gelmann EP. The ubiquitin-proteasome pathway and its role in cancer. J Clin Oncol 2005;23:4776-4789.
Martinez ED, Pattabiraman N, Danielsen M. Analysis of the hormone-binding domain of steroid receptors using chimeras generated by homologous recombination. Exp Cell Res 2005;308:320-333.
Menne S, Cote PJ, Korba BE, Butler SD, George AL, Tochkov IA, Delaney DE, IV, Xiong S, Gerin JL, Tennant BC. Antiviral Effect of Oral Administration of Tenofovir Disoproxil Fumarate in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection. Antivir. Agents Chemother 2005;49:2720-8.
McDonnell K, Bowden ET, Cabal-Manzano R, Hoxter B, Riegel AT, Wellstein A. Vascular leakage in chick embryos after expression of a secreted binding protein for fibroblast growth factors. Lab Invest 2005;85:747-755.
Mishra L, Shetty K, Tang Y, Stuart A, Byers SW. The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer. Oncogene 2005;24:5775-5789.
Nalbandian A, Pang AL, Rennert OM, Chan WY, Ravindranath N, Djakiew D. A novel function of differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression. Differentiation 2005;73:385-396.
North SH, Nakai H. Host factors that promote transpososome disassembly and the PriA-PriC pathway for restart primosome assembly. Mol Microbiol 2005;56:1601-1616.
Okuse C, Rinaudo JA, Farrar K, Wells F, Korba BE. Enhancement of antiviral activity against hepatitis C virus in vitro by interferon combination therapy. Antiviral Res 2005;65:23-34.
Papadopoulos V. Cholesterol homeostasis and infertility: the liver X receptor connection. Endocrinology 2005;146:2517-2518.
Park K, Song KH, Kyun Chung H, Kim H, Wook Kim D, Hun Song J, Suk Hwang E, Sook Chung H, Park SH, Bae I, Kyu Lee I, Choi HS, Shong M. CR6-interacting factor 1 interacts with orphan nuclear receptor Nur77 and inhibits its transactivation. Mol Endocrinol. 2005;19:12-24.
Rui H LeBaron MJ. Creating tissue microarrays by cutting-edge matrix assembly. Expert Rev Med Devices 2005;2:673-680.
Song LN Gelmann EP. Interaction of beta-catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor. J Biol Chem 2005;280:37853-37867.
Shah S, Naimul Islam M, Sivanesan, D, Rivzi I, Herrell, R, Aranda, A, Moras D, Welsh J and Byers S. The Molecular Basis of Vitamin D Receptor and β-Catenin Cross Regulation. Mol. Cell 2006;21:799-809. (MISR, TCSR, MASR)
Stoica GE, Franke TF, Wellstein A, Morgan E, Czubayko F, List HJ, Reiter R, Martin MB, Stoica A. Heregulin-beta1 regulates the estrogen receptor-alpha gene expression and activity via the ErbB2/PI 3-K/Akt pathway. Oncogene 2005;24:1964-
Sultan AS, Xie J, LeBaron MJ, Ealley EL, Nevalainen MT, Rui H. Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. Oncogene 2005;24:746-760.
Suprynowicz FA, Disbrow GL, Simic V, Schlegel R. Are transforming properties of the bovine papillomavirus E5 protein shared by E5 from high-risk human papillomavirus type 16? Virology 2005;332:102-113.
Tilli MT, Reiter R, Oh AS, Henke RT, McDonnell K, Gallicano GI, Furth PA, Riegel AT. Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator amplified in breast cancer 1 leads to altered proliferation of mammary epithelial cells in transgenic mice. Mol Endocrinol 2005;19:644-656.
Uren A, Fallen S, Yuan H, Usubutun A, Kucukali T, Schlegel R, Toretsky JA. Activation of the canonical Wnt pathway during genital keratinocyte transformation: a model for cervical cancer progression. Cancer Res 2005;65:6199-6206.
Uren A, Toretsky JA. Pediatric malignancies provide unique cancer therapy targets. Curr Opin Pediatr 2005;17:14-19.
Wang C, Fan S, Li Z, Fu M, Rao M, Ma Y, Lisanti MP, Albanese C, Katzenellenbogen BS, Kushner PJ, Weber B, Rosen EM, Pestell RG. Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity. Cancer Res 2005;65:6557-6567.
Williams SM, Disbrow GL, Schlegel R, Lee D, Threadgill DW, Lambert PF. Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high risk HPV oncogene. Cancer Res. 2005;65:6534-6542.
Yang M, Schneller SW, Korba BE. 5' Homoneplanocin A inhibits hepatitis B and C. J. Med. Chem. 2005;48:5043-6.
Yin Y, Russell RG, Dettin LE, Bai R, Wei ZL, Kozikowski AP, Kopelovich L, Glazer RI. Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis. Cancer Res 2005;65:3950-3957.
Yin Y, Bai R, Russell RG, Beildeck ME, Xie Z, Kopelovich L, Glazer RI. Characterization of medroxyprogesterone and DMBA-induced multilineage mammary tumors by gene expression profiling. Mol Carcinog 2005;44:42-50.
Zhang Y, Fan S, Meng Q, Ma Y, Katiyar P, Schlegel R, Rosen EM. BRCA1 interaction with human papillomavirus oncoproteins. J Biol Chem 2005;280:33165-33177.
Zhang P, Korba BE, Hosmane RS. Synthesis and In Vitro Anti-Hepatitis B and C Virus Activities of Ring-Expanded ("Fat") Nucleobase Analogues Containing the Imidazo[4,5-e][1,3]diazepine-4,8-dione Ring System. Bioorganic Med. Chem. Lett. 2005;15:5397-401.
