Growth Regulation of Cancer Program
Overview | Leaders | Research | Publications
Selected Publications
2004
Allen J, Khwaja F, Djakiew D. Gene therapy of prostate xenograft tumors with a p75NTR lipoplex. Anticancer Res 2004;24:2997-3003.
Amri H, Li W, Drieu K, Papadopoulos V. Identification of the adrenocorticotropin and ginkgolide B-regulated 90-kilodalton protein (p90) in adrenocortical cells as a serotransferrin precursor protein homolog (adrenotransferrin). Endocrinology 2004;145:1802-1809.
Baege AC, Disbrow GL, Schlegel R. IGFBP-3, a marker of cellular senescence, is overexpressed in human papillomavirus-immortalized cervical cells and enhances IGF-1-induced mitogenesis. J Virol 2004;78:5720-5727.
Bouras T, Lisanti MP, Pestell RG. Caveolin-1 in breast cancer. Cancer Biol Ther 2004;3:931-941.
Bowden ET and Riegel AT. Tetracycline-regulated expression of hammerhead ribozymes in vivo. Methods Mol Biol 2004;252:179-194.
Burbelo P, Wellstein A, Pestell RG. Altered Rho GTPase signaling pathways in breast cancer cells. Breast Cancer Res Treat 2004;84:43-48.
Chen HW, North SH, Nakai H. Properties of the PriA helicase domain and its role in binding PriA to specific DNA structures. J Biol Chem 2004;279:38503-38512.
Ciancio A, Smedile A, Rizzetto M, Lagget M, Gerin J, and Korba B. Identification of HBV DNA sequences that are predictive of response to lamivudine therapy. Hepatology 2004;39:64-73.
D'Amico M, Wu K, Fu M, Rao M, Albanese C, Russell RG, Lian H, Bregman D, White MA, Pestell RG. The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements. Cancer Res 2004;64:4122-4130.
Diallo S, Lecanu L, Greeson J, Papadopoulos V. A capillary gas chromatography/mass spectrometric method for the quantification of hydroxysteroids in human plasma. Anal Biochem 2004;324:123-130.
Fu M, Wang C, Zhang X, Pestell RG. Signal transduction inhibitors in cellular function12. Methods Mol Biol 2004;284:15-36.
Fu M, Rao M, Wu K, Wang C, Zhang X, Hessien M, Yeung YG, Gioeli D, Weber MJ, Pestell RG. The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity. J Biol Chem 2004;279:29436-29449.
Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 2004;145:5439-5447.
Fu M, Wang C, Zhang X, Pestell RG. Acetylation of nuclear receptors in cellular growth and apoptosis. Biochem Pharmacol 2004;68:1199-1208.
Gelmann EP, Semmes O.J. Expression of genes and proteins specific for prostate cancer. J Urol 2004;172:S23-S26.
Giatzakis C, Papadopoulos V. Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity. Endocrinology 2004;145:1113-1123.
Henke RT, Haddad BR, Kim SE, Rone JD, Mani A, Jessup JM, Wellstein A, Maitra, A, Riegel AT. Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma. Clin Cancer Res 2004;10:6134-6142.
Hernandez EM, Chan CH, Xu B, Notario V, Richert JR. Role of an internal ribosome entry site in the translational control of the human transcription factor Sp3. Int J Oncol 2004;24:719-724.
Hulit J, Wang C, Li Z, Albanese C, Rao M, Di Vizio D, Shah S, Byers SW, Mahmood R, Augenlicht LH, Russell R, Pestell RG. Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol 2004;24:7598-7611.
Iyer RP, Jin Y, Roland A, Morrey JD, Mounir S, Korba BE. Phosphorothioate Di- and Tri-nucleotides as a Novel Class of Anti-HBV Agents. Antivir Agents Chem Chemother. 2004;48:2199-2205.
Iyer RP, Roland A, Jin Y, Mounir S, Korba, BE, Julander, JG, Morrey, JD. Anti-hepatitis B virus activity of ORI-9020, a novel phosphorothioate dinucleotide, in a transgenic mouse model. Antivir Agents Chem Chemother. 2004;48: 2318-2320.
Jacob JR, Korba BE, You JE, Tennant BC, Kim Y-H. Korean Medicinal Plant Extracts Exhibit Antiviral Potency Against Viral Hepatitis. J. Altern. Complement. Med. 2004;10: 1019-26.
Jacob JR, Korba BE, Cote PJ, Toshkov I, Delaney WE IV, Gerin JL, Tennant BC. Suppression of Lamivudine-Resistant B-domain mutants by Adefovir Dipivoxil in the Woodchuck Hepatitis Virus Model. Antivir. Res. 2004;63:115-121.
Jacob JR, Sterczer A, Toshkov IA, Yeager AE, Korba BE, Cote PJ, Buendia MA, Gerin JL, Tennant BC. Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors. Hepatology 2004;39:1008-16.
Khwaja F, Allen J, Lynch J, Andrews P, Djakiew D. Ibuprofen inhibits survival of bladder cancer cells by induced expression of the p75NTR tumor suppressor protein. Cancer Res 2004;64:6207-6213.
Kim JS, Lee C, Foxworth A, Waldman T. B-Raf is dispensable for K-Ras-mediated oncogenesis in human cancer cells. Cancer Res 2004;64:1932-1937.
Koehler NK, Yang CY, Varady J, Lu Y, Wu XW, Liu M, Yin D, Bartels M, Xu BY, Roller P P, Long YQ, Li P, Kattah M, Cohn ML, Moran K, Tilley E, Richert JR, Wang S. Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein. J Med Chem 2004;47:4989-4997.
Korba BE, Cote PJ, Menne S, Toshkov I, Baldwin BH, Wells FV, Tennant BC, Gerin JL. Clevudine Therapy with Vaccine Inhibits Progression of Chronic Hepatitis and Delays Onset of Hepatocellular Carcinoma in Chronic Woodchuck Hepatitis Virus Infection. Antivir. Ther. 2004;9:937-952.
Krueger KE, Ghosh AK, Krom BP, Cihlar RL. Deletion of the NOT4 gene impairs hyphal development and pathogenicity in Candida albicans. Microbiology 2004;150:229-240.
Kruppa M, Krom BP, Chauhan N, Bambach AV, Cihlar RL, Calderone RA. The two-component signal transduction protein Chk1p regulates quorum sensing in Candida albicans. Eukaryot Cell 2004;3:1062-1065.
Lecanu L, Yao W, Teper GL, Yao ZX, Greeson J, Papadopoulos V. Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity. Steroids 2004;69:1-16.
Lee C, Kim JS, Waldman T. PTEN gene targeting reveals a radiation-induced size checkpoint in human cancer cells. Cancer Res 2004;64:6906-6914.
Li E, Zhou P, Petrin Z, Singer SM. Mast cell-dependent control of Giardia lamblia infections in mice. Infect Immun 2004;72:6642-6649.
Li W, Amri H, Huang H, Wu C, Papadopoulos V. Gene and protein profiling of the response of MA-10 Leydig tumor cells to human chorionic gonadotropin. J Androl 2004;25:900-913.
Liu MC, Marshall JL, Pestell RG. Novel strategies in cancer therapeutics: targeting enzymes involved in cell cycle regulation and cellular proliferation. Curr Cancer Drug Targets 2004;4:403-424.
Martin MB, Angeloni SV, Garcia-Morales P, Sholler PF, Castro-Galache MD, Ferragut JA, Saceda M. Regulation of estrogen receptor-alpha expression in MCF-7 cells by taxol. J Endocrinol 2004;180:487-496.
Moran KM, Crusio RH, Chan CH, Grekova MC, Richert JR. Human transcription factor Sp3: genomic structure, identification of a processed pseudogene, and transcript analysis. Gene 2004;341:235-247.
Munson AM, Haydon DH, Love SL, Fell GL, Palanivel VR, Rosenwald AG. Yeast ARL1 encodes a regulator of K+ influx. J Cell Sci 2004;117:2309-2320.
Nevalainen MT, Xie J, Torhorst J, Bubendorf L, Haas P, Kononen J, Sauter G, Rui H. Signal transducer and activator of transcription-5 activation and breast cancer prognosis. J Clin Oncol 2004;22:2053-2060.
Nishanian TG, Waldman T. Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor. Biochem Biophys Res Commun 2004;323:91-97.
Nishanian TG, Kim JS, Foxworth A, Waldman T. Suppression of tumorigenesis and activation of Wnt signaling by bone morphogenetic protein 4 in human cancer cells. Cancer Biol Ther 2004;3:667-675.
Oh A, List HJ, Reiter R, Mani A, Zhang Y, Gehan E, Wellstein A, Riegel AT. The nuclear receptor coactivator AIBI mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells. Cancer Res 204;64:8299-8308.
Olcese VA, Chen Y, Schlegel R, Yuan H. Characterization of HPV16 L1 loop domains in the formation of a type-specific, conformational epitope. BMC Microbiol 2004;4:29-
Peck JW, Bowden ET, Burbelo PD. Structure and function of human Vps20 and Snf7 proteins. Biochem J 2004;377:693-700.
Reiter R, Oh AS, Wellstein A, Riegel AT. Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity. Oncogene 2004;23:403-409.
Rinaudo JA, Gerin JL. Cross-species hybridization: characterization of gene expression in woodchuck liver using human membrane arrays. J Med Virol 2004;74:300-313.
Song LN, Coghlan M, Gelmann EP. Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor. Mol Endocrinol 2004;18:70-85.
Taylor KL, Shelby R, Gelmann E, McGuire C. Quality of life and trial adherence among participants in the prostate, lung, colorectal, and ovarian cancer screening trial. J Natl Cancer Inst 2004;96:1083-1094.
Tennant BC, Toshkov IA, Peek SF, Jacob JR, Menne S, Hornbuckle WE, Schinazi RD, Korba BE, Cote PJ, Gerin JL. Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection. Gastroenterology. 2004;127:S283-93.
Toretsky J, Levenson A, Weinberg IN, Tait JF, Uren A, Mease RC. Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death. Nucl Med Biol 2004;31:747-752.
Uren A, Wolf V, Sun YF, Azari A, Rubin JS, Toretsky JA. Wnt/Frizzled signaling in Ewing sarcoma. Pediatr Blood Cancer 2004;43:243-249.
Uren A, Tcherkasskaya O, Toretsky JA. Recombinant EWS-FLI1 oncoprotein activates transcription. Biochemistry 2004;43:13579-13589.
Waldman TA. Gene targeting in cultured human cells. Methods Mol Biol 2004;241:163-174.
Wang C, Fu M, Pestell RG. Histone acetylation/deacetylation as a regulator of cell cycle gene expression. Methods Mol Biol 2004;241:207-216.
Wang C, Li Z, Fu M, Bouras T, Pestell RG. Signal transduction mediated by cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential. Cancer Treat Res 2004;119:217-237.
Wang Y, Menne S, Baldwin BH, Tennant BC, Gerin JL, Cote PJ. Kinetics of viremia and acute liver injury in relation to outcome of neonatal woodchuck hepatitis virus infection. J Med Virol 2004;72:406-415.
Yao ZX, Han Z, Drieu K, Papadopoulos, V. Ginkgo biloba extract (Egb 761) inhibits beta-amyloid production by lowering free cholesterol levels. J Nutr Biochem 2004;15:749-756.
Zhang Y, Glass A, Bennett N, Oyama KA, Gehan E, Gelmann EP. Long-term outcomes after radical prostatectomy performed in a community-based health maintenance organization. Cancer 2004;100:300-307.
