Experimental Therapeutics Program
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Selected Publications
2006
Abrishamchian R, Kanhai D, Zwets E, Nie L, Cardarelli M. Low birth weight or diagnosis, which is a higher risk?--A meta-analysis of observational studies. Eur J Cardiothorac Surg 2006;30(5):700-705.
Adhikari S, Toretsky JA, Yuan L, Roy R. Magnesium, essential for base excision repair enzymes, inhibits substrate binding of N-methylpurine-DNA glycosylase. J Biol Chem 2006;6;281(40):29525-32.
Baek, HJ, Kim SS, Da Silva FM, Volpe EA, Evans S, Mishra B, Mishra L, Marshall B. Inactivation of TGF-β signaling in lung cancer results in increased CDK4 activity that can be rescued by BETA2SP. Biochemical and Biophysical Research Communications 2006;11;346(4):1150-7.
Banovac F, Wilson E, Zhang H, Cleary K. Needle biopsy of anatomically unfavorable liver lesions with an electromagnetic navigation assist device in a computed tomography environment. J Vasc Interv Radiol 2006;17(10):1671-1675.
Bek MJ, Wang X, Asico LD, Jones JE, Zheng S, Li X, Eisner GM, Grandy DK, Carey RM, Soares-da-Silva P, Jose PA. Angiotensin-II type 1 receptor-mediated hypertension in D4 dopamine receptor-deficient mice. Hypertension 2006;47(2):288-295.
Binet JL, Caligaris-Cappio F, Catovsky D, Cheson B, Davis T, Dighiero G, Dohner H, Hallek M, Hillmen P, Keating M, Montserrat E, Kipps TJ, Rai K. Perspectives on the use of new diagnostic tools in the treatment of chronic lymphocytic leukemia. Blood 2006;107(3):859-861.
Blum KA, Johnson JL, Niedzwiecki D, Piro LD, Saven A, Peterson BA, Byrd JC, Cheson BD. Prolonged follow-up after initial therapy with 2-chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: results of Cancer and Leukemia Group B Study 9153. Cancer 2006;107(12):2817-2825.
Boulares H, Zoltoski A, Kandan S, Akbulut T, Yakovlev A, Oumouna M. Correlation between decreased sensitivity of the Daudi lymphoma cells to VP-16-induced apoptosis and deficiency in DNAS1L3 expression. Biochem Biophys Res Commun 2006;341(2):653-662.
Chen S, Crawford M, Day RM, Briones VR, Leader JE, Jose PA, Lechleider RJ. RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation. J Biol Chem 2006;281(3):1765-70.
Cheson BD. Radioimmunotherapy of non-Hodgkin's lymphomas. Curr Drug Targets 2006;7(10):1293-1300.
Cheson BD. CLL response criteria. Clin Adv Hematol Oncol 2006;4(5):4-5.
Cheson BD. Monoclonal antibody therapy for B-cell malignancies. Semin Oncol 2006;33(2 Suppl 5):S2-14.
Cheson BD. Monoclonal antibody therapy of chronic lymphocytic leukemia. Cancer Immunol Immunother 2006;55(2):188-196.
Cheson BD, Canellos GP. The cancer and leukemia group B lymphoma committee. Clin Cancer Res 2006;12(11 Pt 2):3572s-5s.
Cheson BD, Greenberg PL, Bennett JM, Lowenberg B, Wijermans PW, Nimer SD, Pinto A, Beran M, de Witte TM, Stone RM, Mittelman M, Sanz GF, Gore SD, Schiffer CA, Kantarjian H. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 2006;108(2):419-425.
Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. J Proteome Res 2006;5(11):3135-3144.
Cleary K, Melzer A, Watson V, Kronreif G, Stoianovici D. Interventional robotic systems: applications and technology state-of-the-art. Minim Invasive Ther Allied Technol 2006;15(2):101-113.
Di Giovanni S, Knights CD, Rao M, Yakovlev A, Beers J, Catania J, Avantaggiati ML, Faden AI. The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration. EMBO J 2006;25(17):4084-4096.
Faler BJ, Macsata RA, Plummer D, Mishra L, Sidawy AN. Transforming growth factor-beta and wound healing. Perspect Vasc Surg Endovasc Ther 2006;18(1):55-62.
Golestaneh N, Tang Y, Katuri V, Mishra L, Mishra B. Cell Cycle deregulation and loss of stem cell phenotype in the Subventricular Zone of TGF-β adaptor elf-/- mouse brain. Brain Research 2006;1108:45-53.
Han B, Obradovic Z, Hu ZZ, Wu CH, Vucetic S. Substring selection for biomedical document classification. Bioinformatics 2006;22(17):2136-2142.
He AR, Marshall JL. Clinical experiences with G17DT in gastrointestinal malignancies. Expert Rev Anticancer Ther 2006;6(4):487-492.
Henke RT, Eun KS, Maitra A, Paik S, Wellstein A. Expression analysis of mRNA in formalin-fixed, paraffin-embedded archival tissues by mRNA in situ hybridization. Methods 2006;38(4):253-262.
Hodak SP, Huang C, Clarke D, Burman KD, Jonklaas J, Janicic-Kharic N. Intravenous methimazole in the treatment of refractory hyperthyroidism. Thyroid 2006;16(7):691-695.
Hodge JW, Greiner JW, Tsang KY, Sabzevari H, Kudo-Saito C, Grosenbach DW, Gulley JL, Arlen PM, Marshall JL, Panicali D, Schlom J. Costimulatory molecules as adjuvants for immunotherapy. Front Biosci 2006;11:788-803.
Hogrefe RI, Lebedev AV, Zon G, Pirollo KF, Rait A, Zhou Q, Yu W, Chang EH. Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2. Nucleosides Nucleotides Nucleic Acids 2006;25(8):889-907.
Hudgens DP, Taylor C, Batts TW, Patel MK, Brown ML. Discovery of diphenyl amine based sodium channel blockers, effective against hNav1.2. Bioorg Med Chem 2006;14(24):8366-8378.
Hwang J, Marshall JL. Targeted therapy for colorectal cancer. Curr Opin Investig Drugs 2006;7(12):1062-1066.
Jonklaas J, Sarlis NJ, Litofsky D, Ain KB, Bigos ST, Brierley JD, Cooper DS, Haugen BR, Ladenson PW, Magner J, Robbins J, Ross DS, Skarulis M, Maxon HR, Sherman SI. Outcomes of patients with differentiated thyroid carcinoma following initial therapy. Thyroid 2006;16(12):1229-1242.
Juweid ME, Cheson BD. Positron-emission tomography and assessment of cancer therapy. N Engl J Med 2006;354(5):496-507.
Kim SS, Shetty K, Katuri V, Kitisin K, Baek HJ, Tang Y, Marshall B, Johnson LB, Mishra B, Mishra L. TGF-β Signaling Pathway Inactivation and Cell Cycle Deregulation in the Development of Gastric Cancer: Role of the β-Spectrin, BETA2SP. Biochemical and Biophysical Research Communications 2006;344(4):1216-23.
Kitsin K, and Mishra L. Molecular biology of colorectal cancer: New targets. Semi Oncol, Supp 2006;11:S14-23.
Ko SH, Jochnowitz N, Lenkowski PW, Batts TW, Davis GC, Martin WJ, Brown ML, Patel MK. Reversal of neuropathic pain by alpha-hydroxyphenylamide: a novel sodium channel antagonist. Neuropharmacology 2006;50(7):865-873.
Liu H, Hu ZZ, Torii M, Wu C, Friedman C. Quantitative assessment of dictionary-based protein named entity tagging. J Am Med Inform Assoc 2006;13(5):497-507.
Lohmueller KE, Wong LJ, Mauney MM, Jiang L, Felder RA, Jose PA, Williams SM. Patterns of genetic variation in the hypertension candidate gene GRK4: ethnic variation and haplotype structure. Ann Hum Genet 2006;70(Pt 1):27-41.
Mani A, Oh AS, Bowden ET, Lahusen T, Lorick KL, Weissman AM, Schlegel R, Wellstein A, Riegel AT. E6AP mediates regulated proteasomal degradation of the nuclear receptor coactivator amplified in breast cancer 1 in immortalized cells. Cancer Res 2006;66(17):8680-8686.
Lou E, Marshall J, Aklilu M, Cole D, Chang D, Morse M. A phase II study of active immunotherapy with PANVAC or autologous, cultured dendritic cells infected with PANVAC after complete resection of hepatic metastases of colorectal carcinoma. Clin Colorectal Cancer 2006;5(5):368-371.
Marshall J. Optimum use of biologics and role of maintenance therapy in colon cancer. Semin Oncol 2006;33(6 Suppl 11):S33-S35.
Mishra L, and Marshall B. Adaptor proteins and ubiquinators in TGF-β signaling. Cytokine and Growth Factor Reviews 2006;17(1-2):75-87.
Moussa CE, Tomita Y, Sidhu A. Dopamine D1 receptor-mediated toxicity in human SK-N-MC neuroblastoma cells. Neurochem Int. 2006;48(3):226-34.
Muntener M, Patriciu A, Petrisor D, Mazilu D, Bagga H, Kavoussi L, Cleary K, Stoianovici D. Magnetic resonance imaging compatible robotic system for fully automated brachytherapy seed placement. Urology 2006;68(6):1313-1317.
Nie L, Chu H, Cole SR. A general approach for sample size and statistical power calculations assessing of interventions using a mixture model in the presence of detection limits. Contemp Clin Trials 2006;27(5):483-491.
Nie L, Wu G, Zhang W. Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: a quantitative analysis. Genetics 2006;174(4):2229-2243.
Nie L, Wu G, Brockman FJ, Zhang W. Integrated analysis of transcriptomic and proteomic data of Desulfovibrio vulgaris: zero-inflated Poisson regression models to predict abundance of undetected proteins. Bioinformatics 2006;22(13):1641-1647.
Petrova NV, Wu CH. Prediction of catalytic residues using Support Vector Machine with selected protein sequence and structural properties. BMC Bioinformatics 2006;7:312.
Pirollo KF, Zon G, Rait A, Zhou Q, Yu W, Hogrefe R, Chang EH. Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery. Hum Gene Ther 2006;17(1):117-124.
Pirollo KF, Dagata J, Wang P, Freedman M, Vladar A, Fricke S, Ileva L, Zhou Q, Chang EH. A tumor-targeted nanodelivery system to improve early MRI detection of cancer. Mol Imaging 2006;5(1):41-52.
Rankin ML, Marinec PS, Cabrera DM, Wang Z, Jose PA, Sibley DR. The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4. Mol Pharmacol 2006;69(3):759-769.
Saha T, Vardhini D, Tang Y, Katuri V, Jogunoori W, Volpe EA, Haines D, Sidawy A, Zhou X, Gallicano I, Schlegel R, Mishra B, Mishra L. RING finger-dependent ubiquitination by PRAJA is dependent on TGF-beta and potentially defines the functional status of the tumor suppressor ELF. Oncogene 2006;25(5):693-705.
Sanada H, Yatabe J, Midorikawa S, Hashimoto S, Watanabe T, Moore JH, Ritchie MD, Williams SM, Pezzullo JC, Sasaki M, Eisner GM, Jose PA, Felder RA. Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clin Chem 2006;52(3):352-360.
Smith SM, Johnson JL, Niedzwiecki D, Eder JP, Canellos G, Cheson BD, Bartlett NL, Cancer and Leukemia Group. Sequential doxorubicin and topotecan in relapsed/refractory aggressive non-Hodgkin's lymphoma: results of CALGB 59906. Leuk Lymphoma 2006;47(8):1511-1517.
Tassi E, Wellstein A. The angiogenic switch molecule, secreted FGF-binding protein, an indicator of early stages of pancreatic and colorectal adenocarcinoma. Semin Oncol 2006;33(6 Suppl 11):S50-S56.
Tercyak KP, Donze JR, Prahlad S, Mosher RB, Shad AT. Identifying, recruiting, and enrolling adolescent survivors of childhood cancer into a randomized controlled trial of health promotion: preliminary experiences in the Survivor Health and Resilience Education (SHARE) Program. J Pediatr Psychol 2006;31(3):252-261.
Tercyak KP, Donze JR, Prahlad S, Mosher RB, Shad AT. Multiple behavioral risk factors among adolescent survivors of childhood cancer in the Survivor Health and Resilience Education (SHARE) program. Pediatr Blood Cancer 2006;47(6):825-30.
Tomita Y, Marchenko N, Erster S, Nemajerova A, Dehner A, Klein C, Pan H, Kessler H, Pancoska P, Moll UM. WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization. J Biol Chem 2006;281(13):8600-8606.
Wieghaus KA, Brown ML, Botchwey EA. Novel small molecular inducer of angiogenesis stimulates in vitro wound healing. Nature Biotechnology Winter Symposium on Angiogenesis in Cancer and Vascular Disease. Nat Biotech Short Reports 2006;17.
Wu CH, Apweiler R, Bairoch A, Natale DA, Barker WC, Boeckmann B, Ferro S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Mazumder R, O'Donovan C, Redaschi N, Suzek B. The Universal Protein Resource (UniProt): an expanding universe of protein information. Nucleic Acids Res 2006;34(Database issue):D187-D191.
Wu G, Nie L, Zhang W. Predicted highly expressed genes in Nocardia farcinica and the implication for its primary metabolism and nocardial virulence. Antonie Van Leeuwenhoek 2006;89(1):135-146.
Xie B, Tassi E, Swift MR, McDonnell K, Bowden ET, Wang S, Ueda Y, Tomita Y, Riegel AT, Wellstein A. Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display. J Biol Chem 2006;281(2):1137-1144.
Xu S, Taylor RH, Fichtinger G, Cleary K. Lung deformation estimation and four-dimensional CT lung reconstruction. Acad Radiol 2006;13(9):1082-1092.
Yang Z, Asico LD, Yu P, Wang Z, Jones JE, Escano CS, Wang X, Quinn MT, Sibley DR, Romero GG, Felder RA, Jose PA. D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. Am J Physiol Regul Integr Comp Physiol 2006;290(1):R96-R104
Zhang H, Banovac F, Lin R, Glossop N, Wood BJ, Lindisch D, Levy E, Cleary K. Electromagnetic tracking for abdominal interventions in computer aided surgery. Comput Aided Surg 2006;11(3):127-136.
Zhang W, Culley DE, Nie L, Brockman FJ. DNA microarray analysis of anaerobic Methanosarcina barkeri reveals responses to heat shock and air exposure. J Ind Microbiol Biotechnol 2006;33(9):784-790.
Zhang W, Culley DE, Gritsenko MA, Moore RJ, Nie L, Scholten JC, Petritis K, Strittmatter EF, Camp DG, Smith RD, Brockman FJ. LC-MS/MS based proteomic analysis and functional inference of hypothetical proteins in Desulfovibrio vulgaris. Biochem Biophys Res Commun 2006;349(4):1412-1419.
Zhang W, Gritsenko MA, Moore RJ, Culley DE, Nie L, Petritis K, Strittmatter EF, Camp DG, Smith RD, Brockman FJ. A proteomic view of Desulfovibrio vulgaris metabolism as determined by liquid chromatography coupled with tandem mass spectrometry. Proteomics 2006;6(15):4286-4299.
Zeng C, Wang Z, Li H, Yu P, Zheng S, Wu L, Asico LD, Hopfer U, Eisner GM, Felder RA, Jose PA. D3 dopamine receptor directly interacts with D1 dopamine receptor in immortalized renal proximal tubule cells. Hypertension 2006;47(3):573-9.
Artym VV, Zhang Y, Seillier-Moiseiwitsch F, Yamada KM, and Mueller SC. Dynamic Interactions of Cortactin and MT1-MMP at Invadopodia: Defining the Stages of Invadopodia Formation and Function. Cancer Research 2006;66(6):3034-43.
Bowden ET, Onikoyi E, Slack R, Myoui A, Yoneda T, Yamada KM, and Mueller SC. Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells. Experimental Cell Research 2006;312(8):1240-53.
Coopman PJ, and Mueller SC. The Syk tyrosine kinase: a new negative regulator in tumor growth and progression. Cancer Letters 2006;241(2):159-73.
Katuri V, Tang Y, Li C, Jogunoori W, Deng CX, Rashid A, Sidawy AN, Evans S, Reddy EP, Mishra B, Mishra L. Critical interactions between TGF-beta signaling/ELF, and E-cadherin/beta-catenin mediated tumor suppression. Oncogene 2006;25(13):1871-86.
Modlinger P, Chabrashvili T, Gill PS, Mendonca M, Harrison DG, Griendling KK, Li M, Raggio J, Wellstein A, Chen Y, Welch WJ, and Wilcox CS. RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response. Hypertension 2006;47:238-244.
Ray PE, Tassi E, Liu XH, and Wellstein A. Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome. Am J Physiol Regul Integr Comp Physiol 2006;290:R105-113.
Saha T, Vardhini D, Tang Y, Katuri V, Jogunoori W, Volpe EA, Haines D, Sidawy A, Zhou X, Gallicano I, Schlegel R, Mishra B, Mishra L. RING finger-dependent ubiquitination by PRAJA is dependent on TGF-beta and potentially defines the functional status of the tumor suppressor ELF. Oncogene 2006;25(5):693-705.
Tassi E, Henke RT, Bowden ET, Swift MR, Kodack DP, Kuo AH, Maitra A, and Wellstein A. Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon. Cancer Res 2006;66:1191-1198.
Xie B, Tassi E, Swift MR, McDonnell K, Bowden ET, Wang S, Ueda Y, Tomita Y, Riegel AT, and Wellstein A. Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGFbinding protein by phage display. J Biol Chem 2006;281:1137-1144.
