Experimental Therapeutics Program

Program Leaders

Giuseppe Giaccone, MD, PhD
Anton Wellstein, MD, PhD

Program Overview

The overall mission of the Experimental Therapeutics (ET) Program is to reduce the cancer burden through preclinical and early clinical drug development, to determine optimal treatment approaches, combinations and sequences, and to identify prognostic, predictive and surrogate markers of efficacy and resistance for active agents.

ET has 26 members, including translational and clinical researchers, representing 11 departments at Georgetown University and one at MedStar Washington Hospital Center. The Program is organized by disease and modality groups to focus clinical research activities and prioritize clinical trials.

The Cancer Center has recruited leaders in the field that have enhanced the Program's focus, breadth and depth, and has established the MedStar Georgetown Cancer Network to facilitate clinical research across MedStar institutions. The Program's commitment to increasing accrual to clinical trials is essential. Furthermore, the expansion of trials to other institutions in the MedStar Georgetown Cancer Network is enhancing the availability of cutting-edge clinical research to patients in the catchment area.

Experimental Therapeutics Program members focus on three broad themes:

Theme 1: Targeting known driver pathways of cancer;

Theme 2: Targeting the tumor microenvironment;

Theme 3: Developing novel drugs and biomarkers.


The 2013 Experimental Therapeutics Program members are as follows:

Atkins, Michael, MD (Georgetown Lombardi Deputy Director)
Brown, Milton, MD, PhD
Burman, Kenneth D., MD
Chang, Esther, PhD
Cheson, Bruce, MD
Collins, Sean, MD, PhD
Dakshanamurthy, Siva, PhD
Dawson, Nancy, MD
Deeken, John, MD
Dritschilo, Anatoly, MD
Giaccone, Giuseppe, MD, PhD (Program Leader)
He, Aiwu Ruth, MD, PhD
Hurley, Carolyn, PhD
Jones, Jessica, PhD
Kallakury, Bhaskar, MD
Madhavan, Subha, PhD
Marshall, John, MD
Ng, Jennifer, PhD
Paige, Mikell, PhD
Perry, David J., MD
Pirollo, Kathleen, PhD
Pishvaian, Michael, MD, PhD
Soldin, Offie, PhD
Tan, Ming, PhD
Weiner, Louis M, MD (Georgetown Lombardi Director)
Wellstein, Anton, MD, PhD (Program Leader)