Experimental Therapeutics Program

Program Leaders

Giuseppe Giaccone, MD, PhD
Anton Wellstein, MD, PhD

Program Overview

The overall mission of the Experimental Therapeutics (ET) Program is to reduce the cancer burden through preclinical and early clinical drug development, to determine optimal treatment approaches, combinations and sequences, and to identify prognostic, predictive and surrogate markers of efficacy and resistance for active agents.

ET has 30 full members and 34 associate members, including translational and clinical researchers, representing a variety of departments at Georgetown University and MedStar Health. The Program is organized by disease and modality groups to focus clinical research activities and prioritize clinical trials.

The Cancer Center has recruited leaders in the field that have enhanced the Program's focus, breadth and depth, and has established the MedStar Georgetown Cancer Network to facilitate clinical research across MedStar institutions. The Program's commitment to increasing accrual to clinical trials is essential. Furthermore, the expansion of trials to other institutions in the MedStar Georgetown Cancer Network is enhancing the availability of cutting-edge clinical research to patients in the catchment area.

Experimental Therapeutics Program members focus on three broad themes:

Theme 1: Targeting known driver pathways of cancer;

Theme 2: Targeting the tumor microenvironment;

Theme 3: Developing novel drugs and biomarkers.


Michael Atkins, MD (Georgetown Lombardi Deputy Director)
Milton Brown, MD, PhD
Kenneth D. Burman, MD
Esther Chang, PhD
Bruce Cheson, MD
Sean Collins, MD, PhD
Siva Dakshanamurthy, PhD
Nancy Dawson, MD
Sonia de Assis, PhD
John Deeken, MD
Anatoly Dritschilo, MD
Giuseppe Giaccone, MD, PhD (Program Leader)
Andre Goy, MD
Aiwu Ruth He, MD, PhD
Carolyn Hurley, PhD
Jessica Jones, PhD
Bhaskar Kallakury, MD
Subha Madhavan, PhD
John Marshall, MD
Jennifer Ng, PhD
Andrew Pecora, MD
David J. Perry, MD
Kathleen Pirollo, PhD
Michael Pishvaian, MD, PhD
Scott Rowley, MD
Brandon Smaglo, MD
Jill Smith, MD
Ming Tan, PhD
Chaitra Ujjani, MD
Louis M. Weiner, MD (Georgetown Lombardi Director)
Anton Wellstein, MD, PhD (Program Leader)