Cancer Prevention and Control Program

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Scientific Accomplishments

A large number of scientific accomplishments from the Program have been published over recent years. These include the following, representative of all Specific Aims of the Program:

• Publication of key papers establishing the clinical feasibility and impact of offering rapid genetic counseling and testing to newly diagnosed breast cancer patients (Schwartz et al., 2004; 2005; Tercyak, 2007)
• Publication of first prospective studies evaluating the long-term quality of life impact of prophylactic mastectomy among breast cancer patients (Tercyak et al., 2007; Graves et al., 2007).
• Publication of a data on the impact of participation in lung cancer screening on smoking cessation (Taylor et al., 2007).

• Conduct of the first randomized-controlled trial to evaluate the effectiveness of the most widely used internet-based smoking cessation program (R01 CA104836, Graham).(Graham et al., 2006; Graham et al., 2008)
• Completion of a novel randomized trial of an interactive decision aid designed to promote adherence to risk management guidelines among BRCA1/2 mutation carriers (Kaufman et al., 2003; Schwartz et al., 2005; Schwartz et al., in press; Rini et al., in press).
• Publication of a series of papers describing the results of randomized controlled trials of patient education interventions for informed choice in prostate cancer screening (Taylor et al., 2007; Taylor et al., 2006; Williams et al., 2008).

• Coordination of national collaborative modeling project to inform US Preventive Services Task Force Breast Cancer Screening Guidelines (Mandelblatt et al., in press)
• Completion of a novel cost effectiveness analysis to determine the impact of behavioral interventions for breast cancer survivors (Mandelblatt et al., 2008).