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Growth Regulation of Cancer Program

SELECTED PUBLICATIONS

Achi, M.V., Ravindranath, N., and Dym, M. Telomere length in male germ cells is inversely correlated with telomerase activity. Biol.Reprod., 63: 591-598, 2000.

Ackler, S., Ahmad, S., Tobias, C.A., Johnson, M., and Glazer, R. I. Delayed mammary gland involution in MMTV-AKT1 transgenic mice. Oncogene, 21: 198-206, 2002.

Ahonen ,T.J., Xie, J., LeBaron, M.J., Zhu, J., Nurmi, M., Alanen, K., Rui, H., and Nevalainen, M.T. Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells. J.Biol.Chem., 278: 27287-92, 2003.

Ahonen, T.J., Harkonen, P.L., Rui, H., and Nevalainen, M.T. PRL signal transduction in the epithelial compartment of rat prostate maintained as long-term organ cultures in vitro. Endocrinology, 143: 228-238, 2002.

Albanese, C., Wu, K., D'Amico, M., Jarrett, C., Joyce, D., Hughes, J., Hulit, J., Sakamaki, T., Fu, M., Ben-Ze'ev, A., Bromberg, J.F., Lamberti, C., Verma, U., Gaynor, R.B., Byers, S.W., and Pestell, R.G. IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Mol.Biol.Cell, 14: 585-99, 2003.

Amanatullah, D.F., Zafonte, B.T., and Pestell, R.G. The cell cycle in steroid hormone regulated proliferation and differentiation. Minerva Endocrinol., 27: 7-20, 2002.

Amri, H., Drieu, K., and Papadopoulos, V. Use of ginkgolide B and A ginkgolide-activated response element to control gene transcription: example of the adrenocortical peripheral-type benzodiazepine receptor. Cell Mol.Biol., 48: 633-639, 2002.

Andrews, J., Djakiew, D., Krygier, S., and Andrews, P. Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells. Cancer Chemother.Pharmacol., 50: 277-284, 2002.

Andrews, P.A., Krygier, S., and Djakiew, D. Dihydrotestosterone (DHT) modulates the ability of NSAID's to induce apoptosis of prostate cancer cells. Cancer Chemother.Pharmacol., 49: 179-186, 2002.

Anway, M.D., Ravindranath, N., Dym, M., and Griswold, M.D. Identification of a murine testis complementary DNA encoding a homolog to human A-kinase anchoring protein-associated sperm protein. Biol.Reprod., 66: 1755-1761, 2002.

Bachis, A., Colangelo, A.M., Vicini, S., Doe, P.P., De Bernardi, M.A., Brooker, G., and Mocchetti, I. Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity. J.Neurosci., 21: 3104-3112, 2001.

Baege, A.C., Berger, A., Schlegel, R., Veldman, T., and Schlegel, R. Cervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity. Am.J.Pathol., 160: 1251-7, 2002.

Bansal, R., Chen, H.X., Marshall, J.L., Tan, J., Glazer, R.I., and Wainer, I.W. Detection of a mixed-backbone oligonucleotide (GEM 231) in liver and tumor tissues by capillary electrophoresis. J.Chromatogr.Biomed.Sci.Appl., 750: 129-135, 2001.

Bearss, D.J., Lee, R.J., Troyer, D.A., Pestell, R.G., and Windle, J.J. Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties. Cancer Res., 62: 2077-2084, 2002.

Benitah, S.A., Valeron, P.F., Rui, H., Lacal, J.C. STAT5a Activation Mediates the Epithelial to Mesenchymal Transition Induced by Oncogenic RhoA. Mol.Biol. Cell, 14: 40-53, 2003.

Berger, A.J., Baege, A., Guillemette, T., Deeds, J., Meyer, R., Disbrow, G., and Schlegel, R. Insulin-like growth factor-binding protein 3 expression increases during immortalization of cervical keratinocytes by human papillomavirus type 16 E6 and E7 proteins. Am.J.Pathol., 161: 603-10, 2002.

Boer, A.K., Drayer, A.L., Rui, H., and Vellenga, E. Prostaglandin-E2 enhances EPO-mediated STAT5 transcriptional activity by serine phosphorylation of CREB. Blood, 100: 467-473, 2002.

Bordier, B.B., Marion, P.L., Ohashi, K., Kay, M.A., Greenberg, H.B., Casey, J.L., and Glenn, J.S. A prenylation inhibitor prevents production of infectious hepatitis delta virus particles. J.Virol., 76: 10465-10472, 2002.

Boujrad, N., Vidic, B., Gazouli, M., Culty, M., and Papadopoulos, V. The peroxisome proliferator perfluorodecanoic acid inhibits the peripheral-type benzodiazepine receptor (PBR) expression and hormone-stimulated mitochondrial cholesterol transport and steroid formation in Leydig cells. Endocrinology, 141: 3137-3148, 2000.

Boulares, A.H., Zoltoski, A.J., Sherif, Z.A., Yakovlev, A.G., and Smulson, M.E. Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase-1 in sensitization of fibroblasts to tumor necrosis factor-induced apoptosis. Biochem.Biophys.Res.Commun., 290: 796-801, 2002.

Bowen, C., Birrer, M., and Gelmann, E.P. Retinoblastoma protein-mediated apoptosis after gamma-irradiation. J.Biol.Chem., 277: 44969-44979, 2002.

Bowen, C., Bubendorf, L., Voeller, H.J., Slack, R., Willi, N., Sauter, G., Gasser, T.C., Koivisto, P., Lack, E.E., Kononen, J., Kallioniemi, O.P., and Gelmann, E.P. Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression. Cancer Res., 60: 6111-6115, 2000.

Boyle, B.J., Harris, V.K., Liaudet-Coopman, E.D., Riegel, A.T., and Wellstein, A. Differential regulation of a fibroblast growth factor-binding protein by receptor-selective analogs of retinoic acid. Biochem.Pharmacol., 60: 1677-1684, 2000.

Brandoli, C., Shi, B., Pflug, B., Andrews, P., Wrathall, J.R., and Mocchetti, I. Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord. Brain Res.Mol.Brain Res., 87: 61-70, 2001.

Brown, R.C., Han, Z., Cascio, C., and Papadopoulos, V. Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology. Neurobiol.Aging, 24: 57-65, 2003.

Brown, R.C. and Papadopoulos, V. Role of the peripheral-type benzodiazepine receptor in adrenal and brain steroidogenesis. Int.Rev.Neurobiol., 46: 117-143, 2001.

Brown, R.C., Cascio, C., and Papadopoulos, V. Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and beta-amyloid peptide. J.Neurochem., 74: 847-859, 2000.

Burbelo, P.D., Kisailus, A.E., and Peck, J.W. Detecting protein-protein interactions using Renilla luciferase fusion proteins. Biotechniques, 33: 1044-8, 1050, 2002.

Cascio, C., Brown, R.C., Liu, Y., Han, Z., Hales, D.B., and Papadopoulos, V. Pathways of dehydroepiandrosterone formation in rat brain glia. J. Steroid Biochem.Mol.Biol., 75: 177-186, 2000.

Casey, J.L. RNA editing in hepatitis delta virus genotype III requires a branched double-hairpin RNA structure. J.Virol., 76: 7385-7397, 2002.

Choi, Y., Zhang, J., Murga, C., Yu, H., Koller, E., Monia, B.P., Gutkind, J.S., and Li, W. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells. Oncogene, 21: 5289-5300, 2002.

Clark, J.H., Haridasse, V., and Glazer, R.I. Modulation of the human protein kinase C alpha gene promoter by activator protein-2. Biochemistry, 41: 11847-11856, 2002.

Cote, P.J., Korba, B.E., Miller, R.H., Jacob, J.R., Baldwin, B.H., Hornbuckle, W.E., Purcell, R.H., Tennant, B.C., and Gerin, J.L. Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection. Hepatology, 31: 190-200, 2000.

Cote, P.J., Toshkov, I., Bellezza, C., Ascenzi, M., Roneker, C., Ann, G.L., Baldwin, B. H., Gaye, K., Nakamura, I., Korba, B.E., Tennant, B.C., and Gerin, J.L. Temporal pathogenesis of experimental neonatal woodchuck hepatitis virus infection: increased initial viral load and decreased severity of acute hepatitis during the development of chronic viral infection. Hepatology, 32: 807-817, 2000.

Crooke, E. Escherichia coli DnaA protein--phospholipid interactions: in vitro and in vivo. Biochimie, 83: 19-23, 2001.

Culty, M., Luo, L., Yao, Z.X., Chen, H., Papadopoulos, V., and Zirkin, B.R. Cholesterol transport, peripheral benzodiazepine receptor, and steroidogenesis in aging Leydig cells. J.Androl., 23: 439-447, 2002.

Dadachova, E., Bouzahzah, B., Zuckier, L. S., and Pestell, R. G. Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS). Nucl.Med Biol., 29: 13-18, 2002.

Danielsen, M. Bioinformatics of nuclear receptors. Methods Mol.Biol., 176: 3-22, 2001.

Dees, J.H., Gazouli, M., and Papadopoulos, V. Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells. Reprod.Toxicol., 15: 171-187, 2001.

Dirami, G., Ravindranath, N., Achi, M.V., and Dym, M. Expression of Notch pathway components in spermatogonia and Sertoli cells of neonatal mice. J.Androl., 22: 944-952, 2001.

Djakiew, D. Dysregulated expression of growth factors and their receptors in the development of prostate cancer. Prostate, 42: 150-160, 2000.

Elmendorf, H.G., Singer, S.M., and Nash, T.E. The abundance of sterile transcripts in Giardia lamblia. Nucleic Acids Res., 29: 4674-4683, 2001.

Elmendorf, H.G., Singer, S.M., Pierce, J., Cowan, J., and Nash, T.E. Initiator and upstream elements in the alpha2-tubulin promoter of Giardia lamblia. Mol.Biochem.Parasitol., 113: 157-169, 2001.

Fan, S., Ma, Y.X., Wang, C., Yuan, R.Q., Meng, Q., Wang, J.A., Erdos, M., Goldberg, I. D., Webb, P., Kushner, P.J., Pestell, R.G., and Rosen, E.M. p300 Modulates the BRCA1 inhibition of estrogen receptor activity. Cancer Res., 62: 141-151, 2002.

Faure, J.P., Hauet, T., Han, Z., Goujon, J.M., Petit, I., Mauco, G., Eugene, M., Carretier, M., and Papadopoulos, V. Polyethylene glycol reduces early and long-term cold ischemia-reperfusion and renal medulla injury. J.Pharmacol.Exp.Ther., 302: 861-870, 2002.

Feltes, C.M., Kudo, A., Blaschuk, O., and Byers, S.W. An alternatively spliced cadherin-11 enhances human breast cancer cell invasion. Cancer Res., 62: 6688-6697, 2002.

Feng, L.X., Chen, Y., Dettin, L., Pera, R.A., Herr, J.C., Goldberg, E., and Dym, M. Generation and in vitro differentiation of a spermatogonial cell line. Science, 297: 392-395, 2002.

Feng, L.X., Ravindranath, N., and Dym, M. Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia. J.Biol.Chem., 275: 25572-25576, 2000.

Fu, M., Wang, C., Zhang, X., and Pestell, R. Nuclear receptor modifications and endocrine cell proliferation. J. Steroid Biochem.Mol.Biol. 85: 133-8, 2003.

Fu, M., Wang, C., Wang, J., Zhang, X., Sakamaki, T., Yeung, Y. G., Chang, C., Hopp, T., Fuqua, S. A., Jaffray, E., Hay, R.T., Palvimo, J.J., Janne, O.A., and Pestell, R.G. Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Mol. Cell Biol., 22: 3373-3388, 2002.

Gazouli, M., Han, Z., and Papadopoulos, V. Identification of a peptide antagonist to the peripheral-type benzodiazepine receptor that inhibits hormone-stimulated leydig cell steroid formation. J.Pharmacol.Exp.Ther., 303: 627-632, 2002.

Gazouli, M., Yao, Z.X., Boujrad, N., Corton, J. C., Culty, M., and Papadopoulos, V. Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha. Endocrinology, 143: 2571-2583, 2002.

Gelmann, E.P. Searching for the gatekeeper oncogene of prostate cancer. Crit.Rev.Oncol. Hematol., 27: S11-20, 2003.

Gelmann, E.P., Bowen, C., and Bubendorf, L. Expression of NKX3.1 in normal and malignant tissues. Prostate, 55: 111-117, 2003.

Gelmann, E.P. Molecular biology of the androgen receptor. J.Clin.Oncol., 20: 3001-3015, 2002.

Gelmann, E.P., Steadman, D.J., Ma, J., Ahronovitz, N., Voeller, H.J., Swope, S., Abbaszadegan, M., Brown, K.M., Strand, K., Hayes, R.B., and Stampfer, M.J. Occurrence of NKX3.1 C154T polymorphism in men with and without prostate cancer and studies of its effect on protein function. Cancer Res., 62: 2654-9, 2002.

Gelmann, E.P., Chia, D., Pinsky, P.F., Andriole, G.L., Crawford, E.D., Reding, D., Hayes, R.B., Kramer, B.S., Woodrum, D.L., Gohagan, J.K., and Levin, D.L. Relationship of demographic and clinical factors to free and total prostate-specific antigen. Urology, 58: 561-566, 2001.

Gerin, J.L. Animal models of hepatitis delta virus infection and disease. ILAR.J., 42: 103-106, 2001.

Ghim, S., Newsome, J., Bell, J., Sundberg, J.P., Schlegel, R., and Jenson, A.B. Spontaneously regressing oral papillomas induce systemic antibodies that neutralize canine oral papillomavirus. Exp.Mol.Pathol., 68: 147-151, 2000.

Grekova, M.C., Salerno, K., Mikkilineni, R., and Richert, J.R. Sp3 expression in immune cells: a quantitative study. Lab.Invest., 82: 1131-1138, 2002.

Guha, U., Gomes, W. A., Kobayashi, T., Pestell, R. G., and Kessler, J. A. In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Dev.Biol., 249: 108-120, 2002.

Hardwick, M., Rone, J., Han, Z., Haddad, B., and Papadopoulos, V. Peripheral-type benzodiazepine receptor levels correlate with the ability of human breast cancer MDA-MB-231 cell line to grow in SCID mice. Int.J.Cancer, 94: 322-327, 2001.

Harris, V., Kagan, B. L., Ray, R., Coticchia, C.M., Liaudet-Coopman, E.D.E., Wellstein, A., and Riegel, A.T. Serum induction of the fibroblast growth factor-binding protein (FGF-BP) is mediated through ERK and p38 MAP kinase activation and C/EBP-regulated transcription. Oncogene, 20: 1730-1738, 2001.

Harris, V.K., Coticchia, C.M., Kagan, B.L., Ahmad, S., Wellstein, A., and Riegel, A.T. Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways. J.Biol.Chem., 275: 10802-10811, 2000.

Harris, V.K., Coticchia, C.M., List, H.J., Wellstein, A., and Riegel, A.T. Mitogen-induced expression of the fibroblast growth factor-binding protein is transcriptionally repressed through a non-canonical E-box element. J.Biol.Chem., 275: 28539-28548, 2000.

Hauet, T., Han, Z., Wang, Y., Hameury, F., Jayle, C., Gibelin, H., Goujon, J.M., Eugene, M., and Papadopoulos, V. Modulation of peripheral-type benzodiazepine receptor levels in a reperfusion injury pig kidney-graft model. Transplantation, 74: 1507-1515, 2002.

Hawcroft, G., D'Amico, M., Albanese, C., Markham, A.F., Pestell, R.G., and Hull, M.A. Down regulation of b-catenin expression by indomethacin is associated with differential regulation of TCF/LEF target genes in human colorectal cancer cells. Carcinogenesis, 23: 107-114, 2002.

Hermanto, U., Zong, C.S., Li, W., and Wang, L. H. RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix. Mol. Cell Biol., 22: 2345-65, 2002.

Hernandez, E.M., Johnson, A., Notario, V., Chen, A., and Richert, J.R. AUA as a translation initiation site in vitro for the human transcription factor Sp3. J. Biochem.Mol.Biol., 35: 273-282, 2002.

Hirsch, D.S., Pirone, D.M., and Burbelo, P.D. A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. J.Biol.Chem., 276: 875-883, 2001.

Holnthoner, W., Pillinger, M., Groger, M., Wolff, K., Ashton, A.W., Albanese, C., Neumeister, P., Pestell, R.G., and Petzelbauer, P. Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells. J Biol.Chem., 277: 45847-45853, 2002.

Hu, Y.L., Albanese, C., Pestell, R.G., and Jaffe, R.B. Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells. J.Natl.Cancer Inst. 95: 733-4, 2003.

Huang, E., Ishida, S., Pittman, J., Dressman, H., Bild, A., Kloos, M., D'Amico, M., Pestell, R.G., West, M., and Nevins, J.R. Gene expression phenotypic models that predict the activity of oncogenic pathways. Nat.Genet. 34: 226-30, 2003.

Hulit, J., Lee, R.J., Russell, R.G., and Pestell, R.G. ErbB-2-induced mammary tumor growth: the role of cyclin D1 and p27Kip1. Biochem.Pharmacol., 64: 827-836, 2002.

Hurwitz, S.J., Tennant, B.C., Korba, B.E., Liberman, I., Gerin, J.L., and Schinazi, R.F. Viral pharmacodynamic model for (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine (emtricitabine) in chronically infected woodchucks. Antivir.Chem.Chemother., 13: 165-176, 2002.

Jarrett, C.R., Blancato, J., Cao, T., Bressette, D.S., Cepeda, M., Young, P.E., King, C.R., and Byers, S.W. Human APC2 localization and allelic imbalance. Cancer Res., 61: 7978-7984, 2001.

Jayan, G.C. and Casey, J.L. Increased RNA editing and inhibition of hepatitis delta virus replication by high-level expression of ADAR1 and ADAR2. J.Virol., 76: 3819-3827, 2002.

Jayan, G.C. and Casey, J.L. Inhibition of hepatitis delta virus RNA editing by short inhibitory RNA-mediated knockdown of ADAR1 but not ADAR2 expression. J.Virol., 76: 12399-12404, 2002.

Johnson, M.D., Kenney, N., Stoica, A., Hilakivi-Clarke, L., Singh, B., Chepko, G., Clarke, R., Sholler, P.F., Lirio, A.A., Foss, C., Reiter, R., Trock, B., Paik, S., and Martin, M.B. Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nat.Med., 9: 1081-4, 2003.

Jones, J.M. and Nakai, H. Escherichia coli PriA helicase: fork binding orients the helicase to unwind the lagging strand side of arrested replication forks. J.Mol.Biol., 312: 935-947, 2001.

Jones, J.M. and Nakai, H. PriA and phage T4 gp59: factors that promote DNA replication on forked DNA substrates microreview. Mol.Microbiol., 36: 519-527, 2000.

Kagan, B.L., Henke, R.T., Cabal-Manzano, R., Stoica, G.E., Nguyen, Q., Wellstein, A., and Riegel, A.T. Complex regulation of the fibroblast growth factor-binding protein in MDA- MB-468 breast cancer cells by CCAAT/enhancer-binding protein beta. Cancer Res., 63: 1696-705, 2003.

Kim, M.O., Si, Q., Zhou, J.N., Pestell, R.G., Brosnan, C.F., Locker, J., and Lee, S.C. Interferon-beta activates multiple signaling cascades in primary human microglia. J.Neurochem., 81: 1361-1371, 2002.

Kimura, K., Markowski, M., Edsall, L., Spiegel, S., and Gelmann, E.P. Role of ceramide in mediating apoptosis in irradiated LNCaP prostate cancer cells. Cell Death Diff., 10: 240-248, 2003.

Kimura, K. and Gelmann, E.P. Propapoptotic effects of NF-kB in LNCaP prostate cancer cells lead to serine potease activation. Cell Death Diff., 9: 972-980, 2002.

Kimura, K., Markowski, M., Bowen, C., and Gelmann, E.P. Androgen blocks apoptosis of hormone-dependent prostate cancer cells. Cancer Res., 61: 5611-5618, 2001.

Kimura, K. and Gelmann, E.P. Tumor necrosis factor-alpha and Fas activate complementary Fas-associated death domain-dependent pathways that enhance apoptosis induced by gamma-irradiation. J.Biol.Chem., 275: 8610-8617, 2000.

Klouz, A., Sapena, R., Liu, J., Maurice, T., Tillement, J.P., Papadopoulos, V., and Morin, D. Evidence for sigma-1-like receptors in isolated rat liver mitochondrial membranes. Br.J. Pharmacol., 135: 1607-1615, 2002.

Kopelovich, L., Fay, J.R., Glazer, R.I., and Crowell, J.A. Peroxisome proliferator-activated receptor modulators as potential chemopreventive agents. Mol. Cancer Ther., 1: 357-363, 2002.

Kopelovich, L., Glazer, R.I., Steele, V., Lubet, R.A., Malone, W.F., Perloff, M., Kapetanovic, I.M. and Crowell, J.A. Peroxisome proliferator-activated receptor modulators as potential chemopreventive agents, Mol. Cancer Ther. 1: 357-363, 2002.

Korba, B.E., Cote, P., Hornbuckle, W., Schinazi, R., Gangemi, J.D., Tennant, B.C., and Gerin, J.L. Enhanced antiviral benefit of combination therapy with lamivudine and alpha interferon against WHV replication in chronic carrier woodchucks. Antivir.Ther., 5: 95-104, 2000.

Korba, B.E., Cote, P., Hornbuckle, W., Schinazi, R., Gerin, J.L., and Tennant, B.C. Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks. Antiviral Res., 45: 19-32, 2000.

Korba, B.E., Cote, P., Hornbuckle, W., Tennant, B.C., and Gerin, J.L. Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans. Hepatology, 31: 1165-1175, 2000.

Korba, B.E., Schinazi, R.F., Cote, P., Tennant, B.C., and Gerin, J.L. Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks. Antimicrob. Agents Chemother., 44: 1757-1760, 2000.

Krygier, S. and Djakiew, D. Molecular characterization of the loss of p75(NTR) expression in human prostate tumor cells. Mol.Carcinog., 31: 46-55, 2001.

Lauritsen, K.J., List, H.J., Reiter, R., Wellstein, A., and Riegel, A.T. A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells. Oncogene, 21: 7147-7155, 2002.

Lee, H., Park, D.S., Razani, B., Russell, R.G., and Lisanti, M.P. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Am.J.Pathol., 161: 1357-1369, 2002.

Li, H., Degenhardt, B., Tobin, D., Yao, Z.X., Tasken, K., and Papadopoulos, V. Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein. Mol.Endocrinol., 15: 2211-2228, 2001.

Li, H., Yao, Z., Degenhardt, B., Teper, G., and Papadopoulos, V. Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by HIV TAT-CRAC peptide. Proc.Natl.Acad.Sci.U.S.A, 98: 1267-72, 2001.

Li, W., Nadelman, C., Gratch, N.S., Li, W.-Q., Chen, M., Kasahara, N., and Woodley, D. An important role for protein kinase C-alpha in human keratinocyte migration on dermal collagen. Exp. Cell Res., 273: 219-228, 2002.

Li, W., Pretner, E., Shen, L., Drieu, K., and Papadopoulos, V. Common gene targets of Ginkgo biloba extract (EGb 761) in human tumor cells: relation to cell growth. Cell Mol.Biol., 48: 655-662, 2002.

Li, W., Hyun, T., Heller, M., Yam, A., Flechner, L., Pierce, J.H., and Rudikoff, S. Activation of insulin-like growth factor I receptor signaling pathway is critical for mouse plasma cell tumor growth. Cancer Res., 60: 3909-3915, 2000.

Lin, W., Albanese, C., Pestell, R.G., and Lawrence, D.S. Spatially discrete, light-driven protein expression. Chem.Biol. 9: 1347-53, 2003.

List, H.J., Lauritsen, K.J., Reiter, R., Powers, C., Wellstein, A., and Riegel, A.T. Ribozyme targeting demonstrates that the nuclear receptor coactivator AIB1 is a rate-limiting factor for estrogen-dependent growth of human MCF-7 breast cancer cells. J.Biol.Chem., 276: 23763-23768, 2001.

List, H.J., Reiter, R., Singh, B., Wellstein, A., and Riegel, A.T. Expression of the nuclear coactivator AIB1 in normal and malignant breast tissue. Breast Cancer Res.Treat., 68: 21-28, 2001.

List, H.J., Smith, C.L., Martinez, E., Harris, V.K., Danielsen, M., and Riegel, A.T. Effects of antiandrogens on chromatin remodeling and transcription of the integrated mouse mammary tumor virus promoter. Exp. Cell Res., 260: 160-165, 2000.

Liu, M.C. and Gelmann, E.P. P53 gene mutations: case study of a clinical marker for solid tumors. Semin.Oncol, 29: 246-257, 2002.

Liu, M.M., Albanese, C., Anderson, C.M., Hilty, K., Webb, P., Uht, R. M., Price, R.H., Jr., Pestell, R.G., and Kushner, P.J. Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression. J.Biol.Chem., 277: 24353-24360, 2002.

Mallei, A., Shi, B., and Mocchetti, I. Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons. Mol.Pharmacol., 61: 1017-1024, 2002.

Marshall-Batty, K.R. and Nakai, H. Trans-targeting of phage Mu repressor is promoted by conformational changes that expose its ClpX-recognition determinant. J.Biol.Chem., 278: 1612-1617, 2003.

Martin, M.B., Voeller, H.J., Gelmann, E.P., Lu, J., Stoica, G.E., Hebert, E.J., Reiter, R., Singh, B., Danielsen, M., Pentecost, E., and Stoica, A. Role of cadmium in the regulation of AR gene expression and activity. Endocrinology, 143: 263-275, 2002.

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