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Program Overview

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Program Leader

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Program Members

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Scientific Accomplishments

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Selected Publications

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Home » Research

Growth Regulation of Cancer Program

SCIENTIFIC ACCOMPLISHMENTS

Nuclear Receptor Coactivators    
Members of the LCCC have a long history of contributing significantly to the study of nuclear receptors in cancer. Members of the GRC Program have published in several areas related to nuclear receptors and their coactivators. Moreover, the study of nuclear receptors also provides a topic for interprogrammatic collaborations particularly with members of the Breast Cancer Program.

  • The Role of AIB1 in Human Cancers (Anna Riegel)

  • b-Catenin is a Nuclear Receptor Coregulator (Edward Gelmann, Stephen Byers)

  • The Effects of Heavy Metals in Nuclear Receptor Activation (Mary Beth Martin)

The Regulation of Expression and Function of Tumor Suppressors
The GRC Program now focuses on the role and inactivation of suppressor genes and the role of viruses in specific cancers including cervical cancer.

  • Regulation of P53 Function by Posttranslational Modification (Maria Laura Avantagiatti)

  • Targeting Suppressor Gene Inactivation – The Development of an HPV Vaccine (Richard Schlegel)
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