Home » Research

Cancer Genetics and Epidemiology Program

SELECTED PUBLICATIONS

Ahmed, M.N., Kim, K., Haddad, B., Berchuck, A., and Qumsiyeh, M.B. Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma. Cancer Genet.Cytogenet., 116: 15, 2000.

Audrain, J., Tercyak, K.P., Goldman, P., and Bush, A. Recruiting adolescents into genetic studies of smoking behavior. Cancer Epidemiol.Biomarkers Prev., 11: 249-52, 2002.

Batanian, J.R., Cavalli, L.R., Aldosari, N.M., Ma, E., Sotelo-Avila, C., Ramos, M.B., Rone, J.D., and Thorpe, C.M. Evaluation of pediatric osteosarcomas by classical cytogenetic and CGH analyses. Mol. Pathol., 55:389-93, 2002.

Batanian, J., Brink, D.S., Thorpe, C.M., and Haddad, B.R. Case of lipoblastoma with two derivative chromosomes 8 containing homogeneously staining-like regions and a review of the literature: lipoblastoma and chromosome. Cancer Genet.Cytogenet., 125: 10-13, 2001.

Bauer, A.J., Cavalli, L.R., Rone, J., Francis, G.L., Burch, H.B., Tuttle, R.M., Ringel, M.D., Stratakis, C.A., and Haddad, B.R. Evaluation of adult papillary thyroid carcinomas by comparative genomic hybridization and microsatellite instability analysis. Cancer Genet.Cytogenet., 135: 182-186, 2002.

Benkendorf, J.L., Prince, M.B., Rose, M., DeFina, A., and Hamilton, H. Does indirect speech promote non-directive genetic counseling? Semin.Med.Genet., 106: 199-207, 2001.

Blancato, J. and Dickson, R.B. c-Myc gene amplification in breast cancer. In S. Brooks and A. Harris (eds.), Breast Cancer Research Protocols, Humana Press, In press 2003.

Blancato, J. and Haddad, B. Fluorescence in situ hybridization (FISH) in pathology. In H. F. L. Mark (ed.), Medical Cytogenetics, pp. 141-164. New York: Karger Press, 2000.

Block, K.I., Constantinou, A., Hilakivi-Clarke, L., Hughes, C., Tripathy, D., and Tice, J.A. Point-Counterpoint: Soy intake for breast cancer patients. Integrative Cancer Therapies, 1: 90-100, 2002.

Bouker, K. and Hilakivi-Clarke, L.A. Genistein: does it prevent or promote breast cancer? Environ.Health Perspect., 108: 701-708, 2000.

Bradshaw, D., Schammel, C.M., Posch, P., Steiner, N.K., and Hurley, C.K. Development of informatics tools for complex gene systems: Killer immunoglobulin-like receptor genes. Tissue Antigens, 61: 118-135, 2003.

Bradshaw, D., Gans, C.P., Jones, P., Rizzuto, G.A., Steiner, N., Mitton, W., Ng, J., Koester, R., Hartzman, R.J., and Hurley, C.K. Novel HLA-A locus alleles including A*01012, A*0306, A*0308, A*2616, A*2617, A*3009, A*3206, A*3403, A*3602 and A*6604. Tissue Antigens, 59: 325-327, 2002.

Burdett, L., Cao, K., Zhang, G.H., and Fernandez-Vina, M. Twenty-eight novel HLA class I alleles. Eur.J.Immunogenet., 28: 342, 2001.

Butkiewicz, D., Rusin, M., Enewold, L., Shields, P. G., Chorazy, M., and Harris, C. C. Genetic polymorphisms in DNA repair genes and risk of lung cancer. Carcinogenesis, 22: 593-597, 2001.

Cabanes, A., DeAssis, S., Gustafsson, J.-A., and Hilakivi-Clarke, L.A. Maternal high n-6 polyunsaturated fatty acid intake during pregnancy increases voluntary alcohol intake and hypothalamic estrogen receptor alpha and beta levels among female offspring. Dev.Neurosci., 22: 488-493, 2000.

Cao, K., Hollenbach, J.A., Shi, X.J., Shi, W.X., Chopek, M., and Fernandez-Vina, M. Analysis of the frequencies of HLA-A, B and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum.Immunol., 62: 1009-1030, 2001.

Chen, D., Tang, T., Pulyaeva, H., Slack, R., Tu, B., Wagage, D., Li, L., Perlee, L., Ng, J., Hartzman, R.J., and Hurley, C.K. Relative HLA-DRB1*04 allele frequencies in the five major populations of the United States and six new DRB1*04 alleles. Hum.Immunol., 63: 665-672, 2002.

Clarke, R., Liu, M.C., Bouker, K.B., Gu, Z., Lee, R.Y., Zhu, Y., Skaar, T.C., Gomez, B., O'Brien, K., Wang, Y., and Hilakivi-Clarke, L. Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling. Oncogene, 20: 7316-39, 2003.

Clarke, R., Hilakivi-Clarke, L.A., and Trock, B. Dietary and environmental sources of estrogenicity and breast cancer risk. Biologist, 48: 21-26, 2001.

Collins, M., Tang, T., Slack, R., Sintasath, D.M., Hartzman, R.J., Ng, J., and Hurley, C.K. The relative frequencies of HLA-DRB1*01 alleles in the major U.S. populations. Tissue Antigens, 55: 48-52, 2000.

Coopman, P.J., Do, M.T.H., Barth, M., Bowden, E.T., Hayes, A.J., Basyuk, E., Blancato, J., Bezza, P.R., McLeskey, S.W., Mangeat, P., and Mueller, S.C. Spleen tyrosine kinase Syk suppresses malignant growth of human breast cancer cells. Nature, 406: 742-747, 2000.

Coquillard, G.J., Tang, T.F., Steiner, N., Perlee, L., Ng, J., Hartzman, R.J., and Hurley, C.K. DRB3 alleles with variations in the annealing sites of commonly used amplification primers. Tissue Antigens, 55: 558-563, 2000.

Cox, L.S., Africano, N.L., Tercyak, K.P., and Taylor, K.L. Nicotine dependence treatment for patients with cancer. Cancer, 98: 632-44, 2003.

Davidson, B.J., Root, W.A., and Trock, B.J. Age and survival from squamous cell carcinoma of the oral tongue. Head Neck, 23: 273-279, 2001.

de Assis S., Ambrosone C.B., Wustrack S., Krishnan S., Freudenheim J.L., and Shields P.G. Microsomal epoxide hydrolase variants are not associated with risk of breast cancer. Cancer Epidemiol. Biomarkers Prev. 11:1697-8, 2002

Deming, S., Nass, S., Dickson, R.B., and Trock, B.J. C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance. Br.J.Cancer, 83: 1688-1695, 2000.

Ellexson-Turner, M.E., Leffell, M.S., Zachary, A.A., Turner, S., Bennett, T., Sidebottom, D.A., Cao, K., Fernandez-Vina, M., and Hildebrand, W. Sequence-based typing of HLA-class I alleles in Alaskan Yupik Eskimo. Hum.Immunol., 62: 639-644, 2001.

Ellis, E.M., Hoyer, R.J., Costello, C.N., Mshana, R.N., Quakyi, I. A., Mshana, M.N., Diaby, B., Traore, T., Johnson, A.H., and Hurley, C.K. HLA-B allele frequencies in Cote d'Ivoire defined by direct DNA sequencing: identification of HLA-B*1405, B*4410, and B*5302. Tissue Antigens, 57: 339-343, 2001.

Ellis, J.M., Mack, S.J., Leke, F.R.G., Quakyi, I.A., Johnson, A.H., Slack, R., and Hurley, C.K. Diversity is demonstrated in class I HLA-A and HLA-B alleles in Cameroon, Africa: description of HLA-A*03012, *2612, *3006 and HLA-B*1403, *4016, *4703. Tissue Antigens, 56: 291-302, 2000.

Ellis, J., Steiner, N., Kossman, C., Henson, V., Mitton, W., Koester, R., Ng, J., Hartzman, R.J., and Hurley, C.K. Seventeen more novel HLA-A locus alleles. Tissue Antigens, 55: 369-373, 2000.

Epstein L.H., Jaroni J.L., Paluch R.A., Leddy J.J., Vahue H.E., Hawk L., Wileyto E.P., Shields P.G., and Lerman C. Dopamine transporter genotype as a risk factor for obesity in African-American smokers. Obes. Res. 10: 1232-40, 2002.

Felder, R.A., Sanada, H., Yu, P.-Y., Wang, W., Xu, J., Hazen-Martin, D., Wong, L.-J.C., Carey, R.M., and Jose, P.A. Activating mutations in G protein-related kinase 4 in human essential hypertension. Proc.Natl.Acad.Sci.U.S.A., 99: 3872-3877, 2002.

Feng, Z., Tian, D., and Goldman, R. A sensitive immunofluorescence assay for detection of p53 protein in the sputum. Methods Mol.Med., 75: 389-95, 2003.

Ferreira, M., Sahibzada, N., Shi, M., Panico, W., Niedringhaus, M., Wasserman, A., Kellar, K.J., Verbalis, J., and Gillis, R.A. CNS site of action and brainstem circuitry responsible for the intravenous effects of nicotine on gastric tone. J.Neurosci., 22: 2764-2779, 2002.

Ferreira, M., Sing, A., Dretchen, K.L., Kellar, K.J., and Gillis, R.A. Brainstem nicotinic receptor subtypes that influence intragastric and arterial pressures. J.Pharmacol.Exp.Ther., 294: 230-238, 2000.

Gans, C.P., Bradshaw, D., Jones, P.F., Mitton, W., Koester, R., Ng, J., Hartzman, R.J., and Hurley, C.K. Eight new HLA-A alleles associated with antigens in the A2 CREG. Tissue Antigens, 59: 133-135, 2002.

Gans, C.P., Mitton, W., Ng, J., Hartzman, R.J., and Hurley, C.K. Seven new HLA-B alleles associated with antigens in the B7 CREG. Tissue Antigens, 59: 229-231, 2002.

Gans, C.P., Mitton, W., Ng, J., Hartzman, R.J., and Hurley, C.K. Description of six new HLA-B alleles in the 5C CREG including a B*58 intron two sequence. Tissue Antigens, 59: 145-147, 2002.

Gans, C. P., Tang, T.F., Slack, R., Ng, J., Hartzman, R.J., and Hurley, C.K. DRB1*14 diversity and DRB3 associations in four major population groups in the United States. Tissue Antigens, 59: 364-369, 2002.

Goldman, R., and Shields, P.G. Food mutagens. J.Nutr. 33: 965S-973S, 2003.

Goldman, R., Enewold, L., Pellizzari, E., Beach, J.B., Bowman, E.D., Krishnan, S., and Shields, P.G. Smoking increase carcinogenic polycyclic aromatic hydrocarbons in human lung tissue. Can.Res., 61: 6367-6371, 2001.

Goldman, R., Day, B., Carver, T.A., Mauthe, R.J., Turteltaub, K.W., and Shields, P.G. Quantitation of benzol[a]Pyrenees-DNA adducts by postlabeling with 14C-acetic anhydride and accelerator mass spectrometry. Chem.Biol.Interact., 126: 171-183, 2000.

Hancock, D.K., Schwarz, F.P., Song, F., Wong, L.-J.C., and Levin, B.C. Design and use of a peptide nucleic acid for the detection of the heteroplasmic low-frequency MELAS mutation in human mitochondrial DNA. Clin.Chem., 48: 1901-1912, 2002.

Hardwick, M., Cavalli, L.R., Barlow, K., Haddad, B.R., and Papadopoulos, V. Peripheral-type benzodiazepine receptor gene amplification in MDA-231 aggressive breast cancer cells. Cancer Genet.Cytogenet., 2002.

Hardwick, M., Rone, J., Han, Z., Haddad, B., and Papadopoulos, V. Peripheral-type benzodiazepine receptor levels correlate with the ability of human breast cancer MDA-MB-231 cell line to grow in SCID mice. Int.J.Cancer, 94: 322-7, 2001.

Helmberg, W.J., Hegland, J., Hurley, C.K., Maiers, M., Marsh, S.G., Mueller, C., and Rozemuller, E.H. Going back to the roots: effective utilization of HLA typing information for bone marrow registries requires full knowledge of the DNA sequences of the oligonucleotide reagents used in the testing. Tissue Antigens, 56: 99-102, 2000.

Hemmati, P., Sloand, E., Carvallo, C., Albert, M., Yee, C., Fuehrer, M., Blancato, J., Kearns, W., Barrett, J., Childs, R., Vogel, J., and Dunbar, C. Absence of donor derived keratinocytes stem cells in skin tissues cultures from patients after mobilized peripheral blood hematopoietic stem cell transplantation. Exp.Hematol., 30: 943-949, 2002.

Hemminki, K. and Shields, P.G. Skilled use of DNA polymorphisms as a tool for polygenic cancers. Carcinogenesis, 23: 379-380, 2002.

Hernandez, S.C., Bertolino, M., Xiao, Y., Pringle, K.E., Caruso, F.S., and Kellar, K.J. Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors. J.Pharmacol.Exp.Ther., 293: 962-967, 2000.

Hilakivi-Clarke L. Modulation of pregnancy estrogen levels by maternal dietary exposure to soy isolate or n-3 polyunsaturated fatty acid and breast cancer risk among female rat offspring. Clin. Cancer Res., 2002.

Hilakivi-Clarke, L., Cabanes, A., Olivo, S., Kerr, L., Bouker, K., and Clarke, R. Do estrogens always increase breast cancer risk? J.Steroid Biochem.Mol.Biol., 80: 163-174, 2002.

Hilakivi-Clarke, L., Cho, E., Cabanes, A., DeAssis, S., Olivo, S., Helferich, W., Lippman, M.E., and Clarke, R. Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring. Clin.Cancer Res., 8: 3601-3610, 2002.

Hilakivi-Clarke, L.A., Cho, E., DeAssis, S., Olivo, S.E., Ealley, E., Bouker, K., Welch, J.N., Khan, G., Clarke, R., and Cabanes, A. Maternal and prepubertal diet, mammary development and breast cancer risk. J.Nutr., 131: 154S-157S, 2001.

Hilakivi-Clarke L., Forsen T., Eriksson J.G., Luoto R., Tuomilehto J., Osmond C. et al. Tallness and overweight during childhood have opposing effects on breast cancer risk. Br.J.Cancer 85:1680-4, 2001.

Hilakivi-Clarke, L.A. Estrogens, BRCA1 and breast cancer. Cancer Res., 60:4993-5001, 2000.

Hilakivi-Clarke, L.A., Cho, E., Onojafe, I., and Clarke, R. Maternal exposure to tamoxifen during pregnancy increases mammary tumorigenesis among female offspring. Clin.Cancer Res., 6: 305-308, 2000.

Hollenbach, J.A., Thomson, G., Fernandez-Vina, M., Cao, K., Erlich, H.A., Bugawan, T., Winkler, C., and Klitz, W. HLA diversity, differentiation and haplotype evolution in Mesoamerican Natives. Hum.Immunol., 62: 378-390, 2001.

Hurley, C.K., M. Fernandez Vina, and Setterholm M. Maximizing optimal hematopoietic stem cell donor selection from registries of unrelated adult volunteers. Tissue Antigens 61:415-424, 2003.

Hurley, C., L.A. Baxter Lowe, B. Logan, C. Karanes, C. Anasetti, D. Weisdorf, and D.L. Confer. National Marrow Donor Program HLA matching guidelines for unrelated marrow transplants. Biol Blood Marrow Transplant, 9: 610-5, 2003.

Hurley, C.K., Tang, T., Ng, J., and Hartzman, R. J. HLA typing by molecular methods. In N. R. Rose, E. Conway de Macario, J.D. Folds, H.C. Lane, and R.M. Nakamura (eds.), Manual of Clinical Laboratory Immunology, 6th ed Washington, DC: ASM Press, 2002.

Hurley, C.K. HLA diversity: detection and impact on unrelated hematopoietic stem cell donor characterization and selection. Int. J. Hematol., 76: 152-154, 2002.

Hurley, C.K., Steiner, N., Gans, C.P., Kosman, C., Mitton, W., Koester, R., Jones, P., Edson, S., Rizzuto, G. A., Hartzman, R.J., Ng, J., and Rodriguez-Marino, S. Twelve novel HLA-B*15 alleles carrying previously observed sequence motifs are placed into B*15 subgroups. Tissue Antigens, 57: 474-477, 2001.

Hurley, C.K., Baxter-Lowe, L., Begovich, A.B., Fernandez-Vina, M., Noreen, B., Ng, J., Hartzman, R.J., Hegland, J., et al. The extent of HLA Class II allele level disparity in unrelated bone marrow transplantation: Analysis of 1259 National Marrow Donor Program donor-recipient pairs. Bone Marrow Transplant., 25: 385-393, 2000.

Hurley, C.K., Maiers, M., Ng, J., Wagage, D., Hegland, J., Baisch, J., Endres, R., Fernandez-Vina, M., Heine, U., Hsu, S., Kamoun, M., Mitsuishi, Y., Monos, D., Noreen, H., Perlee, L., Rodriguez-Marino, S., Smith, A., Stastny, P., Trucco, M., Yang, S.Y., Yu, N., Holsten, R., Hartzman, R.J., and Setterholm, M. Large-scale DNA-based typing of HLA-A and HLA-B at low resolution is highly accurate, specific, and reliable. Tissue Antigens, 55: 352-358, 2000.

Hurley, C.K., Baxter-Lowe, L.A., Begovich, A.B., Fernandez-Vina, M., Noreen, H., Schmeckpeper B., et al. The extent of HLA class II allele level disparity in unrelated bone marrow transplantation: analysis of 1,259 national marrow donor program donor-recipient pairs. Bone Marrow Transplant. 25: 385-393, 2000.

Hussain, S.P., Amstad, P., Raja, K., Sawyer, M., Hofseth, L.J., Shields, P.G., Hewer, A., Phillips, D.H., Ryberg, D., Haugen, A., and Harris, C.C. Related article mutability of p53 hotspot codons to benzo (a) pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung. Cancer Res., 61: 6350-6355, 2001.

Hussain, S.P., Raja, K., Amstad, P., Sawyer, M., Trudel, L.J., Wogan, G.N., Hofseth, L.J., Shields, P.G., Billiar, T.R., Trautwein, C., Hohler, T., Galle, P.R., Phillips, D. H., Markin, R., Marrogi, A.J., and Harris, C. C. Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. Proc.Natl.Acad.Sci.U.S.A., 97: 12770-12775, 2000.

Jarrett, C.R., Blancato, J., Cao, T., Young, P., King, C.R., and Byers, S. Human APC2 localization and allelic imbalance. Cancer Res., 61: 7978-7984, 2001.

Johnson, A.H., Wade, J.A., Hartzman, R.J., and Hurley, C.K. HLA: MHC of man and transplantation immunology. In J.B. Henry (ed.), Clinical Diagnosis and Management by Laboratory Methods, 20th ed. Philadelphia, PA: W.B. Saunders, Co. 2000.

Kuehl, K.S. and Loffredo, C.A. A population-based study of L-transposition of the great arteries: possible associations with environmental factors. Teratology, 67: 162-167, 2003.

Kuehl, K.S. and Loffredo, C.A. Risk factors for heart disease associated with abnormal sidedness. Teratology, 66: 242-248, 2002.

Lacbawan, F.L., Tifft, C.J., Amaya, M., Pennybacker, M., Weistein, S., and Wong, L.-J.C. Clinical heterogeneity in mitochondrial DNA deletion disorders: a diagnostic challenge. Am.J.Med.Genet., 95: 272-274, 2000.

Lapham, V., Weiss, J.O., Kozma, C., Benkendorf, J., and Wilson, M. The gap between practice and genetics education of health professionals: HuGEM survey results. Genet.Med., 24: 226-231, 2000.

Lee, J.H., Smith, A.G., Yunis, E.J., Selvakumar, A., Ferrone, S., McKinney, S., Lee, J.H., Fernandez-Vina, M., Hansen, J.A., and Yunis, E.J. Molecular characterization of the HLA-Cw*0409N allele. Human Immunol., 63: 295-300, 2002.

Leffell, M.S., Fallin, M.D., Erlich, H.A., Fernandez-Vina, M., Hildebrand, W.H., Mack, S.J., and Zachary, A.A. HLA antigens, alleles and haplotypes amon the Yup'ik Alaska natives: report of the ASHI Minority Workshops, Part II. Human Immunol., 63: 295-300, 2002.

Lerman, C., Shields, P.G., Wileyto, E..P, Audrain, J., Pinto, A., Hawk, L., Krishnan, S., Niaura, R., and Epstein, L. Pharmacogenetic investigation of smoking cessation treatment. Pharmacogenetics, 12:627-634, 2002.

Lerman, C., Croyle, R.T., Tercyak, K.P., and Hamann, H. Genetic testing: psychological aspects and implications. J.Consult Clin.Psychol., 70: 784-97, 2002.

Lerman, C., Caporaso, N.E., Bush, A., Zheng, Y L., Audrain, J.E., Main, D., and Shields, P.G. Tryptophan hydroxylase gene variant and smoking behavior. Am.J.Med.Genet., 105: 518-520, 2001.

Lerman, C., Schwartz, M.D., Lin, T.H., Narod, S., and Lynch, H.T. The influence of psychological distress on use of genetic testing for cancer risk. J.Consult.Clin.Psychol., 65: 414-420, 2000.

Lerman, C., Caporaso, N.E., Audrain, J., Main, D., Boyd, N.R., and Shields, P.G. Interacting effects of the serotonin transporter gene and neuroticism in smoking practices and nicotine dependence. Mol.Psychiatry, 5: 189-192, 2000.

Lin, Y.S., Hoyer, R.J., Tang, T.F., Ng, J., Hartzman, R.J., and Hurley, C.K. Detection of four novel alleles: DRB*1130, DRB1*13072, DRB1*1315 and DRB1*1331. Tissue Antigens, 55: 92-96, 2000.

Loffredo, C.A. and Frank, C. Liver cancer: risk factors and prevention. In P.G. Shields (ed.), Methods for Cancer Risk Assessment: From the Laboratory to the Clinic. New York: Marcel Dekker, Inc., 2001.

Liu, J., Cavalli, L.R., Haddad, B.R., and Papadopoulos, V. Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RIalpha associated protein. Gene, 10: 1-10, 2003.

Maiers, M., Schreuder, G.M.T., Lau, M., Marsh, S.G.E., Fernandez-Vina, M., Noreen, H., Setterholm, M., Hurley, C.K. Use of a neural network to assign serologic specificities to HLA-A, -B and -DRB1 allelic products. Tissue Antigens 62:21-47, 2003.

Maiers, M., Hurley, C.K., Perlee, L., Fernandez-Vina, M., Baisch, J., Cook, D., Fraser, P., Heine, U., Hsu, S., Leffell, M.S., Maurer, D., Noreen, H., Tang, T., Trucco, M., Yang, S.Y., Yu, N., Hartzman, R.J., Setterholm, M., Winden, T., Shepherd, D., and Hegland, J. Maintaining updated DNA-based HLA assignments in the National Marrow Donor Program bone marrow registry. Rev. Immunogenet. 2: 449-460, 2000.

McCann S.E., Moysich K.B., Freudenheim J.L., Ambrosone C.B., and Shields P.G. The risk of breast cancer associated with dietary lignans differs by CYP17 genotype in women. J Nutr. 132: 3036-41, 2002.

McComsey, G., Tan, D.J., Wong, L.-J.C., Wilson, E., and Wong, L.-J.C. Analysis of the entire mitochondrial DNA genome in the peripheral blood lymphocytes of HIV-infected subjects with or without lipoatrophy reveals novel point mutations. AIDS, 16: 513-518, 2002.

Meyer, E.L., Xiao, Y., and Kellar, K.J. Agonist regulation of rat alpha3beta4 nicotinic acetylcholine receptors stably expressed in human embryonic kidney 293 cells. Mol.Pharmacol., 60: 568-576, 2001.

Miller, B.T., Rubino, D.M., Driggers, P.H., Haddad, B., Cisar, M., Gray, K., and Segars, J.H. Expression of the Brx protooncogene is increased in epithelial ovarian neoplasms compared to normal ovaries. Am.J.Obstet.Gynecol., 182: 286-295, 2000.

Moysich, K.B., Ambrosone, C.B., Mendola, P., Kostyniak, P., Greizerstein, H., Vena, J.E., Menezes, R.J., Swede, H., Shields, P.G., and Freudenheim, J.L. Exposures associated with serum organochlorine levels among postmenopausal women from western New York State. Am.J.Ind.Med., 41: 102-110, 2002.

Noreen, H., Yu, N., Setterholm, M., Ohashi, M., Baisch, J., Endres, R., Fernandez-Vina, M., Heine, U., Hsu, S., Kamoun, M., Mitsuishi, Y., Monos, D., Perlee, L., Rodriguez-Marino, S., Smith, A., Yang, S.Y., Shipp, K., Hegland, J., and Hurley, C.K. Validation of DNA-based HLA-A and HLA-B testing of volunteers for a bone marrow registry through parallel testing with serology. Tissue Antigens, 57: 221-229, 2001.

Perry, D.C., Xiao, Y., Nguyen, H.N., Musachio, J.L., Dávila-García, M.I., and Kellar, K.J. Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography. J.Neurochem., 82: 468-471, 2002.

Petersdorf, E.W., Kollman, C., Hurley, C.K., Dupont, B., Nademanee, A., Begovich, A.B., Weisdorf, D., and McGlave, P. Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for CML: The U.S. National Marrow donor Program Experience. Blood, 98: 2922-2929, 2001.

Pimtanothai, N., Charoenwongse, P., Mutirangura, A., and Hurley, C.K. Distribution of HLA-B alleles in nasopharyngeal carcinoma patients and normal controls in Thailand. Tissue Antigens, 59: 223-225, 2002.

Pimtanothai, N., Hurley, C.K., Leke, R., Kiltz, W., and Johnson, A.H. HLA-DR and -DQ polymorphism in Cameroon. Tissue Antigens, 58: 1-8, 2001.

Pimtanothai, N., Para, M., Johnson, A.H., David, C.S., and Hurley, C.K. Assessing the binding of four plasmodium falciparum T helper cell epitopes to HLA-DQ and induction of T cell responses in HLA-DQ transgenic mice. Infect.Immun., 68: 1366-1373, 2000.

Pimtanothai, N., Rizzuto, G.A., Slack, R., Steiner, N., Kosman, C., Jones, P.F., Koester, R., Ng, J., Hartzman, R.J., and Hurley, C.K. The diversity of alleles encoding HLA-B40: the relative frequencies in U.S. populations and description of five novel alleles. Human Immunol., 61: 808-815, 2000.

Posch, P.E., Hartzman, R.J., and Hurley, C.K. Histocompatibility: HLA and other systems. In S.N. Wickramasinghe and J. McCullough (eds.), Blood and Bone Marrow Pathology, pp. 665-707. Edinburgh: Harcourt Brace, 2002.

Prochazka M., Granath F., Ekbom A., Shields P.G., and Hall P. Lung cancer risks in women with previous breast cancer. Eur.J. Cancer. 38: 1520-5, 2002.

Rosenberg, M.A., Ning, Y., Meck, J.M., Blancato, J., and Biesecker, L. The detection of chromosome aberrations by a whole genome microsatellite screen. Am.J.Hum.Genet., 66: 419-427, 2000.

Schmid-Braz, A.T., Cavalli, L.R., Cornelio, D.A., Wuicik, L., Ribeiro, E.M.S.F., Bleggi-Torres, L.F., Lima, R.S., de Andrade Urban, C., Haddad, B.R., and Cavalli, I.J. Comprehensive cytogenetic evaluation of a mature ovarian teratoma case. Cancer Genet.Cytogenet., 132: 165-168, 2002.

Schreuder, G.M.T., Hurley, C.K., Marsh, S.G., Lau, M., Maiers, M., Kollman, C., and Noreen, H. The HLA dictionary 2001: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens. Human Immunology, 62: 826-849, 2001.

Schreuder, G.M.T., Hurley, C.K., Marsh, S.G., Lau, M., Maiers, M., Kollman, C., and Noreen, H. The HLA dictionary 2001: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens. Tissue Antigens, 58: 109-140, 2001.

Schreuder, G.M.T., Hurley, C.K., Marsh, S.G., Lau, M., Maiers, M., Kollman, C., and Noreen, H. The HLA dictionary 2001: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens. Eur.J.Immunogenet., 28: 565-596, 2001.

Schwartz, M.D., Hughes, C., Roth, J., Main, D., Peshkin, B.N., Isaacs, C., Kavanagh, C., and Lerman, C. Spiritual faith and genetic testing decisions among high risk breast cancer probands. Cancer Epid.Biomarkers.Prev., 9: 381-385, 2000.

Shields, P.G. Tobacco smoking, harm reduction, and biomarkers. J.Natl.Cancer Inst., 94: 1435-44, 2002.

Sheilds, P.G. Molecular epidemiology of smoking and lung cancer. Oncogene, 21: 6870-6, 2002.

Sheilds, P.G. Publication bias is a scientific problem with adverse ethical outcomes: the case for a section for null results. Cancer Epidemiol.Biomarkers Prev., 9:771-2, 2000.

Smith, A.C.M., Gropman, A., Bailey-Wilson, J., Goker-Alpan, O., Elsea, S., Blancato, J., Lupski, J., and Potocki, L. Hypercholesterolemia in children with Smith Magenis Syndrome. Genet.Med., 4: 3118-3126, 2002.

Smulson, M.E., Simbulan-Rosenthal, C.M., Boulares, A.H., Yakovlev, A., Stoica, B.A., Iyer, S., Luo, R., Haddad, B., Wang, Z.Q., Pang, T., Jung, M., Dritschilo, A., and Rosenthal, D.S. Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1. Adv.Enzyme Regul., 40: 183-215, 2000.

Steiner, N., Baldassarre, L.A., Koester, R., Ng, J., Hartzman, R.J., and Hurley, C.K. Novel HLA-B alleles formed by an inter-locus recombination with HLA-C: HLA-B*0713 and B*6702. Tissue Antigens, 59: 148-150, 2002.

Steiner, N., Gans, C.P., Kosman, C., Baldassarre, L.A., Edson, S., Jones, P., Rizzuto, G.A., Pimtanothai, N., Koester, R., Mitton, W., Ng, J., Hartzman, R.J., and Hurley, C.K. Novel HLA-B alleles associated with antigens in the 8C creg. Tissue Antigens, 57: 373-375, 2001.

Steiner, N., Gans, C.P., Kosman, C., Bradshaw, D., Koester, R., Menchaca, E., Mitton, W., Ng, J., Hartzman, R.J., and Hurley, C.K. New alleles in the B44 family including B*44022, B*44032, B*4411, B*4420, B*4421, B4424, and B*8301. Tissue Antigens, 57: 376-379, 2001.

Steiner, N., Jones, P., Kosman, C., Edson, S., Rizzuto, G.A., Gans, C.P., Mitton, W., Koester, R., Rodriguez-Marino, S., Ng, J., Hartzman, R.J., and Hurley, C.K. Novel HLA-B alleles associated with antigens in the 7C creg. Tissue Antigens, 57: 486-488, 2001.

Steiner, N., Kosman, C., Jones, P.F., Gans, C.P., Rodriguez-Marino, S., Rizzuto, G.A., Baldassarre, L.A., Edson, S., Koester, R., Sese, D., Mitton, W., Ng, J., Hartzman, R.J., and Hurley, C.K. Twenty nine new HLA-B alleles associated with antigens in the 5C creg. Tissue Antigens, 57: 481-485, 2001.

Steiner, N., Edson, S., Mitton, W., Ng, J., Hartzman, R.J., and Hurley, C.K. Seven novel HLA-A alleles carry previously observed polymorphisms. Tissue Antigens, 56: 551-552, 2000.

Stevens R, Hilakivi-Clarke L. Hypothesis: alcohol exposure in utero and later breast cancer risk. Alcohol Alcoholism 36:276-7, 2001.

Su, Y.A. and Trent, J.M. Isolation of tumor suppressor genes in melanoma by cDNA microarray. In B. J. Nickoloff (ed.), Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring. Methods in Molecular Medicine, pp. 15-29. Totowa, NJ: Human Press, 2001.

Su, Y.A., Bittner, M.L., Chen, Y., Tao, L., Jiang, Y., Zhang, Y.H., Stephan, D.A., and Trent, J.M. Identification of tumor suppressor genes in human melanoma cell lines UACC903, UACC903 (+6), and SRS3 by analysis of expression profiles. Mol.Carcinog., 28: 119-127, 2000.

Tan, D.J., Bai, R.K., and Wong, L.-J.C. Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res., 62: 972-976, 2002.

Tang, T.F., Lin, Y.S., Robbins, F.M., Li, L., Sintasath, D.M., Coquillard, G.J., Huang, A.Y., Heine, U., Ng, J., Hartzman, R.J., and Hurley, C.K. Description of fourteen new DRB alleles found in a stem cell donor registry. Tissue Antigens, 59: 63-65, 2002.

Tang, T.F., Wang, R., Slack, R., Lin, Y.S., Li, L., Heine, U., Ng, J., Hartzman, R.J., and Hurley, C.K. DRB1*03 diversity and DRB3 associations in five major population groups in the United States. Hum.Immunol., 63: 221-228, 2002.

Tang, T.F., Huang, A.Y., Pappas, A., Slack, R., Ng, J., Hartzman, R.J., and Hurley, C.K. Relative frequencies of DRB1*11 alleles and their DRB3 associations in five major population groups in a United States bone marrow registry. Hum.Immunol., 61: 820-827, 2000.

Tercyak, K.P., Cox, L.S., and Shields, P.G. Genetic influences on smoking behavior: The role of biomarkers in tobacco control. In S.M. Miller (ed.), Individuals, Families, and the New Genetics New York, NY: W.W. Norton, 2002.

Tilanus, M.G., Hansen, J.A., Hurley, C.K., and (eds) IHWG technical manual. Genomic analysis of the human MHC. Seattle, WA: 1HWG, 2000.

Trock, B.J. Validation of surrogate endpoint biomarkers in prostate cancer chemoprevention trials. Urology, 57: 241-247, 2001.

Trock, B.J. Out of the mouths of babes: oral premalignant lesions and alternative tobacco products. Cancer Epidemiol.Biomarkers Prev., 9: 637-638, 2000.

Wong, L.-J., Lueth, M., Li, X.N., Lau, C.C., and Vogel, H. Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients. Cancer Res., 63: 3866-71, 2003.

Wong, L.-J.C., Herbert, W.S., Zhang, Y.H., Hsu, E., Wong, I.H., Wladyka, C., Woo, M.S., and Bowman, C.M. Prenatal genetic counseling on a woman with advanced maternal age and a family history of a known genetic disease. Changhua J.Med., 7: 75-79, 2002.

Wong, L.-J.C., Liang, M.-H., Kwon, H., Park, J., Bai, R., and Tan, D.J. Comprehensive scanning of the entire mitochondrial genome for mutations. Clin.Chem., 48: 1901-1912, 2002.

Wong, L.-J.C., Wong, I.H., and Liu, A. Intergenerational transmission of pathogenic heteroplasmic mitochondrial DNA. Genet.Med., 4: 78-83, 2002.

Wong, L-J.C. and Bai, R. Real time quantitative PCR analysis of mitochondrial DNA in patients with mitochondrial disease. Am. J. Human Genet. 71, 501, 2002.

Xiao, Y., Smith, R.D., Caruso, F.S., and Kellar, K.J. Blockade of rat alpha3beta4 nicotinic receptor function by methadone, its metabolites, and structural analogs. J.Pharmacol.Exp.Ther., 299: 366-371, 2001.

Yeh, J.J., Yasuda, R.P., Davila-Garcia, M.I., Xiao, Y., Ebert, S., Gupta, A., Kellar, K.J., and Wolfe, B.B. Neuronal nicotinic acetylcholine receptor alpha3 subunit protein in rat brain and sympathetic ganglion measured using a subunit-specific antibody: regional and ontogenic expression. J.Neurochem., 77: 336-346, 2001.

Yeh, J., Ferreira, M., Ebert, S., Yasuda, R.P., Kellar, K.J., and Wolfe, B.B. Axotomy and nerve growth factor regulate levels of neuronal nicotinic acetylcholine receptor alpha3 subunit protein in the rat superior cervical ganglion. J.Neurochem., 79: 258-265, 2001.

Zheng, Y.L., Loffredo, C.A., Yu, Z., Jones, R.T., Krasna, M.J., Alberg, A.J., Yung, R., Perlmutter, D., Enewold, L., Harris, C.H., and Shields, P.G. Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls. Carcinogenesis, 24: 269-274, 2003.