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Selected Publications

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Home » Research

Cancer Genetics and Epidemiology Program

SELECTED PUBLICATIONS

2007 2006 Earlier Publications

2007

  • Abdel-Hamid M, El-Daly M, Molnegren V, El-Kafrawy S, Abdel-Latif S, Esmat G, Strickland GT, Loffredo C, Albert J, Widell A. Genetic diversity in hepatitis C virus in Egypt and possible association with hepatocellular carcinoma. J Gen Virol 2007 (in press).

  • Boudreau HE, Broustas CG, Gokhale PC, Kumar D, Mewani RR, Rone JD, Haddad BR and Kasid U. Expression of BRCC3, a novel cell cycle regulated molecule, is associated with increased phospho- ERK and cell proliferation. Int. J. Mol Med 19:29-39 (2007). *** RB

  • Chen J, Yenokyan G, Jorgensen TJ, Ruczinski I, Yao Y, Alani R, Lieigois N , Hoffman SC, Hoffman-Bolton J, Strickland PT, Hezlzsouer KJ, Alberg AJ: Nonmelanoma skin cancer as a marker of risk for subsequent malignancy: A community-based prospective cohort study. JNCI (submitted), 2007.

  • Jorgensen TJ, Tian H,  Ferguson D,  Joseph IBJK, Menon K, and Frost D: Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth. Cancer Chemother Pharmocol (in press), 2007.

  • Kim JS, Lee C, Bonifant CL, Ressom H, Waldman T (2007). Activation of p53-Dependent Growth Suppression in Human Cells by Mutations in PTEN or PIK3CA. Mol Cell Biol 27(2): 662-677. ***GRC

  • Labib N, Radwan G, Mikhail N, Mohamed MK, El Setouhy M, Loffredo C, Israel E. Comparison of cigarette and waterpipe smoking among female university students in Egypt. Nicotine and Tobacco Research2007 (in press, April 2007 issue).###

  • Ressom HW, Varghese RS, Drake SK, Hortin GL, Abdel-Hamid M, Loffredo CA, and Goldman R (2007). Peak selection from MALDI-TOF mass spectra using ant colony optimization. Bioinformatics. In press. Bioinformatics 1/19/2007 (advance access). ###

  • Tercyak KP, Davis KM, Loffredo CA. Behavioral risk factors among Black and White women newly diagnosed with breast cancer.  Psychooncology. 2007 (in press). ***CC

  • Xu J, Gao M, Fan S, Meng Q, Goldberg ID, Abounader R, Ressom H, Laterra JJ, Rosen EM (2007). Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells. Oncogene. In press. [Epub ahead of print November 13, 2006] ***BC

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2006

  • Adhikari, S., Toretsky, J.A., Yuan, L., Roy, R. Magnesium, essential for base excision repair enzymes, inhibits substrate binding of N-methylpurine-DNA glycosylase.  J Biol Chem., 281, 29525-29532, 2006.***

  • Artym VV, Zhang Y, Seillier-Moiseiwitsch F, Yamada KM and Mueller SC.  Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function.  Cancer Res 2006 Mar 15;66(6):3034-43.

  • Audrain-McGovern J, Al Koudsi N, Rodriguez D, Wileyto EP, Shields PG, Tyndale RF. The role of CYP2A6 in the emergence of nicotine dependence in adolescents. Pediatrics. 2007 Jan;119(1):e264-274. Epub 2006 Nov 27.

  • Audrain-McGovern J, Rodriguez D, Wileyto EP, Schmitz KH, Shields PG.   Effect of team sport participation on genetic predisposition to adolescent smoking progression. Arch Gen Psychiatry. 2006 Apr;63(4):433-441.

  • Ayyad SBA, Radwan G, Israel E , El-Setouhy M, Mohamed MK, Loffredo C. Evaluation of Papanicolaou (Pap) stain for studying micronuclei in buccal cells under field conditions. Acta Cytologica 2006;50: 398-402. ###

  • Bendavid C, Dubourg C, Gicquel I, Pasquier L, Saugier-Veber P, Durou MR, Jaillard S, Frebourg T, Haddad BR, Henry C, Odent S, David V. Molecular evaluation of foetuses with holoprosencephaly shows high incidence of microdeletions in the HPE genes. Hum Genet. 119(1-2):1-8 (2006).

  • Berrettini WH, Wileyto EP, Epstein L, Restine S, Hawk L, Shields P, Niaura R, Lerman C.   Catechol-O-Methyltransferase (COMT) Gene Variants Predict Response to Bupropion Therapy for Tobacco Dependence. Biol Psychiatry. 2006 Jul 27.

  • Blancato JK, Williams MS, Dickson RB.  Fluorescence in situ hybridization assessment of c-myc gene amplification in breast tumor tissues. Methods Mol Med. 2006;120:297-307.***

  • Brooks BP, Meck JM, Haddad BR, Bendavid C, Blain D, Toretsky JA. Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature. BMC Med Genet. 7(1):2 (2006). *** MTDT

  • Chellappan SK, Xiao Y, Tueckmantel W, Kellar KJ, and Kozikowski AP, 2006.  Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. nicotinic ligands of enhanced subtype selectivity.  Journal of Medicinal Chemistry, 49:2673-2676

  • Chen J, Pee D, Ayyagari R, Graubard B, Schairer C, Byrne C, Benichou J, Gail MH. Projecting Absolute Invasive Breast Cancer Risk in White Women: a Model that Includes Mammographic Density. JNCI 2006 98:1215-26.

  • Chung FL.  Tea and Health   Interview with Yukihiko Hara, Mitsui Norin Co., Ltd. Mol Nutr Food Res. 2006 Feb 8;50(2):112 113 [Epub ahead of print]

  • Chung FL. Editorial: Mol. Nutr. Food Res. Mol Nutr Food Res. 2006 Feb 8;50(2):109.

  • Crowe SL, Movsesyan VA, Jorgensen TJ, Kondratyev A: Rapid phosphorylation of histone H2AX following ionotropic glutamate receptor activation.  Europ. J. Neuroscience 23 (9): 2351-2361, 2006.

  • DeMarco TA, Loffredo CA, Sampilo ML, Tercyak KP. On using a cancer center cancer registry to identify newly affected women eligible for hereditary breast cancer syndrome testing: practical considerations. J Genet Couns 2006;15: 129-36.  *** CC

  • Diorio C, Berube S, Byrne C, Masse B, Hebert Croteau N, Yaffe M, Cote G,  Pollak M, Brisson J.   Influence of insulin like growth factors on the strength of the relation of vitamin D and calcium intakes to mammographic breast density. Cancer Res. 2006 Jan 1;66(1): 588 97. 

  • Fan S, Meng Q Auborn K, Carter T, Rosen EM. BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells. British Journal of Cancer, 94: 407-426, 2006.

  • Feng S, Cao J, Zhu W, Song JY LI C, Sheng FJ, Fan S, Eckardt-Schupp F. Mechanisms for ATM mediated downstream gene BRCA1 and RAD51 in signaling pathway of DNA injury repair. Journal of Radiation Research and Radiation Processing, 24: 115-119, 2006.

  • Fitsanakis VA, Owens SE, dos Santos APM, Soldin OP, Aschner M. Manganese transport and neurotoxicity. Metal Ions Biol Med 2006; 9:101-107.

  • Golden R, Pyatt D, Shields PG.   Formaldehyde as a potential human leukemogen: an assessment of biological plausibility. Crit Rev Toxicol. 2006 Feb;36(2):135-153. Review.

  • Hu J, Redden DT, Berrettini WH, Shields PG, Restine SL, Pinto A, Lerman C, Allison DB. No evidence for a major role of polymorphisms during bupropion treatment. Obesity (Silver Spring). 2006 Nov;14(11):1863-1867.

  • Hurley CK, Wagner JE, Setterholm MI and Confer DL.  Advances in HLA: practical implications for selecting adult donors and cord blood units.  Biol Blood Marrow Transplant. 2006 Jan;12(1 Suppl 1):28-33.

  • Jorgensen TJ,  Visvanathan K, Ingo Ruczinski I, Lucy Thuita L, and Helzlsouer KJ: Breast cancer risk is not associated with polymorphic forms of xeroderma pigmentosum genes in a cohort of women from Washington County, Maryland. Breast Cancer Res. Treat. 95:73-80, 2006.

  • Kapasi A, Fan S, Singhal P. p300 modulates HIV-1 gp120-induced apoptosis in human proximal tubular cells: associated with alteration of TGF-beta and Smad signaling. Nephron. Experimental nephrology, 102: e30-38, 2006.

  • Kapasi A, Fan S, Singhal P. Scatter factor mitigates HIV-1 gp120-induced human mesangial cell injury. Nephron. Experimental nephrology, 103: e103-108, 2006.

  • Katiyar P, Ma Y, Fan S, Pestell RG, Furth PA, Rosen EM. Regulation of progesterone receptor signaling by BRCA1 in mammary cancer. Nuclear Receipt Signal, 4: e006, 2006,

  • Kellar, KJ.  Overcoming Inhibitions.  Proc Natl Acad Sci USA. 2006 Sep 5;103(36):13263-4. Epub 2006 Aug 28.

  • Kellar KJ and Xiao Y, 2007.  Neuronal nicotinic receptors: one hundred years of progress.  In: The handbook of Contemporary Neuropharmacology.  Edited by: Sibley D, Hanin I, Kuhar M and Skolnick P.  John Wiley & Sons, Inc., Hoboken, NJ, in press.

  • Koren G, Soldin OP. Therapeutic Drug Monitoring of Antithyroid Drugs in Pregnancy: The Knowledge Gaps. Ther Drug Monit. 2006;28(1):12-13.

  • Kuehl KS, Loffredo CA. A cluster of hypoplastic left heart malformations in Baltimore, Maryland. Pediatr Cardiol 2006;27: 25-31.

  • Lazaro AM, Cao K, Masaberg C, Steiner NK, Xiao Y, Tu B, Turner V, Nickerson P, Stoll S, Schall C, Valdez R, Ng J, Hartzman RJ and Hurley CK.  Twenty-three novel HLA-B alleles identified during intermediate-resolution testing.  Tissue Antigens 2006 Sep;68(3):245-8.

  • Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz  N.   Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clin Pharmacol Ther. 2006 Jun;79(6):600-608. Epub 2006 May 11.

  • Ma YX, Katuyar P, Jones LP, Fan S, Zhang Y, Furth PA, Rosen EM. The Breast Cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells. Molecular Endocrinology, 20: 14-34, 2006.

  • Ma YX, Yuan RQ, Fan S, Hu C, Goldberg ID, Laterra JJ, Rosen EM. Identification of genes that modulate sensitivity of U373MG glioblastoma cells to cis-platinum. Anticancer Drugs. 17: 733-751, 2006.

  • Mandelblatt J, Kreling B, Figeuriedo M and Feng S.  What is the impact of shared decision making on treatment and outcomes for older women with breast cancer?  J Clin Oncol 2006 Oct 20;24(30):4908-13. Epub 2006 Sep 18.

  • Munafo MR, Johnstone EC, Wileyto EP, Shields PG, Elliot KM, Lerman C.  Lack of association of 5-HTTLPR genotype with smoking cessation in a nicotine replacement therapy randomized trial. Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):398-400.

  • Natarajan TG, Ganesan N, Carter-Nolan P, Tucker CA, Shields PG, Adams-Campbell LL. {gamma}-Radiation-Induced Chromosomal Mutagen Sensitivity Is Associated with Breast Cancer Risk in African-American Women: Caffeine Modulates the Outcome of Mutagen Sensitivity Assay. Cancer Epidemiol Biomarkers Prev. 2006 Mar;15(3):437-442.

  • Ohtani M, OkaT, Badyuk M, Xiao Y, Kellar KJ, and Daly KJ, 2006.  Mouse b-TC6 insulinoma cells: high expression of functional {alpha}3b4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release.  Molecular Pharmacolology, 69:899-907

  • Orvisky, E, Drake, SK, Martin, BM, Abdel-Hamid, M, Ressom, H, Varghese, RS, An, Y, Saha, D, Hortin, GL, Loffredo, CA, Goldman, R. (2006) Enrichment of low molecular weight fraction of serum for mass spectrometric analysis of peptides associated with hepatocellular carcinoma. Proteomics, 6, 2895-2902. ###

  • Pan, J., Davis, W., Trushin, N., Amin, S., Nath, R.G., Salem Jr, N., and Chung, F-L.  A solid phase extraction/high performance liquid chromatography-based 32P-postlabeling method for detection of cyclic 1,N2-propanodeoxyguanosine adducts derived from enals.  Analytical Biochemistry, 348, 15-23, 2006.

  • Parise IZ, Haddad BR, Cavalli LR, Pianovski MA, Maggio EM, Parise GA, Watanabe FM, Ioshii SO, Rone JD, Caleffe LG, Filho VO, Figueiredo BC. Neuroblastoma in Southern Brazil: An 11-Year Study. J Pediatr Hematol Oncol. 28(2):82-87 (2006).

  • PG, Sobti RC, Sorensen M, Spinola M, Spitz MR, Strange RC, Stucker I, Sugimura H, To-Figueras J, Tokudome S, Yang P, Yuan JM, Warholm M, Taioli E.   Meta- and Pooled Analysis of GSTT1 and Lung Cancer: A Huge-GSEC Review. Am J Epidemiol. 2006 Sep 25.

  • Pianovski MA, Cavalli LR, Figueiredo BC, Santos SC, Doghman M, Ribeiro RC, Oliveira AG, Michalkiewicz E, Rodrigues GA, Zambetti G, Haddad BR, Lalli E. SF-1 overexpression in childhood adrenocortical tumours. Eur J Cancer. 42(8):1040-3 (2006).

  • Pine SR, Mechanic LE, Bowman ED, Welsh JA, Chanock SC, Shields PG, Harris CC.   MDM2 SNP309 and SNP354 are not associated with lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1559-1561.

  • Rae JM, Creighton CJ, Meck JM, Haddad BR, Johnson MD. MDA-MB-435 cells are derived from M14 Melanoma cells-a loss for breast cancer, but a boon for melanoma research. Breast Cancer Res Treat. 2006 Sep 27; [Epub ahead of print] *** BC

  • Raimondi S, Paracchini V, Autrup H, Barros-Dios JM, Benhamou S, Boffetta P, Cote ML, Dialyna IA, Dolzan V, Filiberti R, Garte S, Hirvonen A, Husgafvel-Pursiainen K, Imyanitov EN, Kalina I, Kang D, Kiyohara C, Kohno T, Kremers P, Lan Q, London S, Povey AC, Rannug A, Reszka E, Risch A, Romkes M, Schneider J, Seow A, Shields PG, Sobti RC, Sorensen M, Spinola M, Spitz MR, Strange RC, Stucker I, Sugimura H, To-Figueras J, Tokudome S, Yang P, Yuan JM, Warholm M and Taioli E.  Meta- and Pooled Analysis of GSTT1 and Lung Cancer:  A Huge-GSEC Review.  Am J Epidemiol.  2006 Sep 25.

  • Ressom, HW, Varghese, RS, Orvisky, E, Drake, SK, Hortin, GL, Abdel-Hamid, M, Loffredo, CA, and Goldman, R (2006). Ant colony optimization for biomarker identification from MALDI-TOF mass spectra. Proceedings of the 28th IEEE Engineering in Medicine and Biology Society Annual International Conference, New York City, NY, 4560-4563.  ###

  • Ressom, H.W., HW, Varghese, RS, Orvisky, E, Drake, SK, Hortin, GL, Abdel-Hamid, M, Loffredo, CA, and Goldman, R (2006). Biomarker identification and rule extraction from mass spectral serum profiles. Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, Toronto, ON, 164-170.  ###

  • Rice JM. Inducible and transmissible genetic events and pediatric tumors of the nervous system.  J. Radiat.  Res., 2006 47 Suppl. B1 – B11.

  • Rosen EM, Fan S and Ma Y.  BRCA1 regulation of transcription.  Cancer Lett. 2006 May 18;236(2):175-85. Epub 2005 Jun 21.

  • Shields PG.   Understanding population and individual risk assessment: the case of polychlorinated biphenyls.  Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):830-839.

  • Shruti Agrawal, Bozena Winnik, Brian Buckley, Lixin Mi, Fung-Lung Chung and Thomas J. Cook.  Simultaneous determination of sulforaphane and its major metabolites from biological matrices with liquid chromatography-tandem mass spectroscopy.  J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Aug 18;840(2):99-107.

  • Soldin OP. Thyroid Function Testing in Pregnancy and Thyroid Disease: Trimester-specific Reference Intervals. Ther Drug Monit. 2006;28(1):8-11.

  • Soldin SJ, Soldin OP, Boyajian AJ, Taskier MS. Pediatric brain natriuretic peptide and N-terminal pro-brain natriuretic peptide reference intervals. Clin Chim Acta. 2006 Apr;366(1-2):304-8. Epub 2005 Dec 19.

  • Tennis M, Krishnan S, Bonner M, Ambrosone CB, Vena JE, Moysich K, Swede H, McCann S, Hall P, Shields PG, Freudenheim JL.  p53 Mutation analysis in breast tumors by a DNA microarray method. Cancer Epidemiol Biomarkers Prev. 2006 Jan;15(1):80-85.

  • Travis LB, Rabkin CS, Brown LM, Allan JM, Alter BP, Ambrosone CB, Begg CB, Caporaso N, Chanock S, DeMichele A, Figg WD, Gospodarowicz MK, Hall EJ, Hisada M, Inskip P, Kleinerman R, Little JB, Malkin D, Ng AK, Offit K, Pui CH, Robison LL, Rothman N, Shields PG, Strong L, Taniguchi T, Tucker MA, Greene MH.   Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. J Natl Cancer Inst. 2006 Jan 4;98(1):15-25.

  • Tseng M, Byrne C, Evers KE, London WT, Daly MB. Acculturation and breast density in foreign-born, US Chinese women.  Cancer Epidemiol Biomarkers Prev. 2006; Jul;15(7):1301-5.

  • Wu K, Giovannucci E, Byrne C, Platz EA, Fuchs C, Willett WC, Sinha R.Meat Mutagens and Risk of Distal Colon Adenoma in a Cohort of U.S. Men Cancer Epidemiol Biomarkers Prev 2006 15: 1120-1125.

  • Wu X, Spitz MR, Amos CI, Lin J, Shao L, Gu J, de Andrade M, Benowitz NL, Shields PG, Swan GE.   Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res. 2006 Jun 15;66(12):5993-5996.

  • Xiao Y, Fan H, Musachio JL, Wei ZL, Chellappan SK, Kozikowski AP and Kellar KJ.  Sazetidine-A, a novel ligand that desensitizes a4b2 nicotinic acetylcholine receptors without activating them.  Mol Pharmacol 2006;70:1454-1460.

  • Xie B, Freudenheim JL, Cummings SS, Singh B, He H, McCann SE, Moysich KB, Shields PG.  Accurate genotyping from paraffin embedded normal tissue adjacent to breast cancer. Carcinogenesis. 2006 Feb;27(2):307-310.

  • Xu J, Gao M, Fan S, Meng Q, Goldberg ID, Abounader R, Ressom H, Laterra JJ, Rosen EM. Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells. Oncogene, in press, 2006.

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Earlier Publications

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