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DoD Breast Cancer Center of Excellence Resources: Recent Publications

Below is a listing of major published studies from 2004 and 2005 examining the relationship between alcohol and breast cancer risk.

Rossner P Jr, Terry MB, Gammon MD, Zhang FF, Teitelbaum SL, Eng SM, Sagiv SK, Gaudet MM, Neugut AI, Santella RM. OGG1 polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):811-5. Read the abstract

Stolzenberg-Solomon RZ, Chang SC, Leitzmann MF, Johnson KA, Johnson C, Buys SS, Hoover RN, Ziegler RG. Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Am J Clin Nutr. 2006 Apr;83(4):895-904. Read the abstract

Boffetta P, Hashibe M, La Vecchia C, Zatonski W, Rehm J. The burden of cancer attributable to alcohol drinking. Int J Cancer. 2006 Mar 23; [Epub ahead of print] Read the abstract

Rosenberg LU, Magnusson C, Lindstrom E, Wedren S, Hall P, Dickman PW. Menopausal hormone therapy and other breast cancer risk factors in relation to the risk of different histological subtypes of breast cancer: a case-control study. Breast Cancer Res. 2006;8(1):R11. Read the abstract

Etique N, Grillier-Vuissoz I, Flament S. Ethanol stimulates the secretion of matrix metalloproteinases 2 and 9 in MCF-7 human breast cancer cells. Oncol Rep. 2006 Mar;15(3):603-8. Read the abstract

Touvier M, Kesse E, Volatier JL, Clavel-Chapelon F, Boutron-Ruault MC. Dietary and cancer-related behaviors of vitamin/mineral dietary supplement users in a large cohort of French women. Eur J Nutr. 2006 Jan 2; [Epub ahead of print] Read the abstract

Gago-Dominguez M, Castelao JE, Pike MC, Sevanian A, Haile RW. Role of lipid peroxidation in the epidemiology and prevention of breast cancer. Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2829-39. Review. Read the abstract

Terry MB, Gammon MD, Zhang FF, Knight JA, Wang Q, Britton JA, Teitelbaum SL, Neugut AI, Santella RM. ADH3 genotype, alcohol intake and breast cancer risk. Carcinogenesis. 2006 Apr;27(4):840-7. Read the abstract

Hanf V, Gonder U. Nutrition and primary prevention of breast cancer: foods, nutrients and breast cancer risk. Eur J Obstet Gynecol Reprod Biol. 2005 Dec 1;123(2):139-49. Review. Read the abstract

Ravn-Haren G, Olsen A, Tjonneland A, Dragsted LO, Nexo BA, Wallin H, Overvad K, Raaschou-Nielsen O, Vogel U. Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study. Carcinogenesis. 2006 Apr;27(4):820-5. Read the abstract

Suzuki R, Ye W, Rylander-Rudqvist T, Saji S, Colditz GA, Wolk A. Alcohol and postmenopausal breast cancer risk defined by estrogen and progesterone receptor status: a prospective cohort study. J Natl Cancer Inst. 2005 Nov 2;97(21):1601-8. Read the abstract

Tjonneland A, Christensen J, Olsen A, Stripp C, Nissen SB, Overvad K, Thomsen BL. Folate intake, alcohol and risk of breast cancer among postmenopausal women in Denmark. Eur J Clin Nutr. 2006 Feb;60(2):280-6. Read the abstract

Terry MB, Zhang FF, Kabat G, Britton JA, Teitelbaum SL, Neugut AI, Gammon MD. Lifetime alcohol intake and breast cancer risk. Ann Epidemiol. 2006 Mar;16(3):230-40. Read the abstract

Gaudet MM, Gammon MD, Santella RM, Britton JA, Teitelbaum SL, Eng SM, Terry MB, Bensen JT, Schroeder J, Olshan AF, Neugut AI, Ambrosone CB. MnSOD Val-9Ala genotype, pro- and anti-oxidant environmental modifiers, and breast cancer among women on Long Island, New York. Cancer Causes Control. 2005 Dec;16(10):1225-34. Read the abstract

Vachon CM, Sellers TA, Janney CA, Brandt KR, Carlson EE, Pankratz VS, Wu FF, Therneau TM, Cerhan JR. Alcohol intake in adolescence and mammographic density. Int J Cancer. 2005 Dec 10;117(5):837-41. Read the abstract

Althuis MD, Fergenbaum JH, Garcia-Closas M, Brinton LA, Madigan MP, Sherman ME. Etiology of hormone receptor-defined breast cancer: a systematic review of the literature. Cancer Epidemiol Biomarkers Prev 2004;13:1558-1568. Read the abstract

Aye MM, Ma C, Lin H, Bower KA, Wiggins RC, Luo J. Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts. Int J Cancer 2004;112:738-746. Read the abstract

Baglietto L, English DR, Gertig DM, Hopper JL, Giles GG. Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort study. BMJ 2005;331:807. Read the abstract

Cerhan JR, Sellers TA, Janney CA, Pankratz VS, Brandt KR, Vacnhon CM. Prenatal and perinatal correlates of adult mammographic breast density. Cancer Epidemiol Biomarkers Prev 2005;14:1502-1508. Read the abstract

Coutelle C, Hohn B, Benesova M, Oneta CM, Quattrochi P, Roth HJ, Schmidt-Gayk H, Schneeweiss A, Bastert G, Seitz HK. Risk factors in alcohol associated breast cancer: alcohol dehydrogenase polymorphism and estrogens. Int J Oncol 2004;25:1127-1132. Read the abstract

Dumeaux V, Lund E, Hjartaker A. Use of oral contraceptives, alcohol, and risk for invasive breast cancer. Cancer Epidemiol Biomarkers 2004;13:1302-1307. Read the abstract

Dumitrescu RG, Shields PG. The etiology of alcohol-induced breast cancer. Alcohol 2005;35:213-225. Read the abstract

Eichbaum MH, Schneeweiss A, Bastert G. Long-term remission of excessive lover metastases in a breast cancer patient with chrinic alcohol abuse using a monotherapy with trastuzumab. Anticancer Drugs 2005;16:199-200. Read the abstract

Etique N, Chardard D, Chesnel A, Flament S, Grillier-Vuissoz I. Analysis of the effects of different alcohols on fcf-7 human breast cancer cells. Ann NY Acad Sci 2004;1030:78-85. Read the abstract

Freudenheim JL, Bonner M, Krishnan S, Ambrosone CB, Graham S, McCann SE, Moysich KB, Bowman E, Nemoto T, Shields PG. Diet and alcohol consumption in relation to p53 mutations in breast tumors. Carcinogenesis 2004;25(6):931-939. Read the abstract

Guenel P, Cyr D, Sabroe S, Lynge E, Merletti F, Ahrens W, Baumgardt-Elms C, Menegoz F, Olsson H, Paulsen S, Simonato L, Wingren G. Alcohol drinking may increase risk of breast cancer in men: a European population-based case-control study. Cancer Causes Control 2004;15:571-580. Read the abstract

Gunzerath L, Faden V, Zakhari S, Warren K. National Institute on Alcohol Abuse and Alcoholism report on moderate drinking. Alcohol Clin Exp Res 2004;28:829-847. Review. Read the abstract

Hartman TJ, Baer DJ, Graham LB, Stone WL, Gunter EW, Parker CE, Albert PS, Dorgan JF, Clevidence BA, Campbell WS, Tomer KB, Judd JT, Taylor PR. Moderate alcohol consumption and levels of antioxidant vitamins and isoprostanes in postmenopausal women. Eur J Clin Nutr 2005;59:161-168. Read the abstract

Hilakivi-Clarke L, Cabanes A, de Assis S, Wang M, Khan G, Shoemaker WJ, Stevens RG. In utero alcohol exposure increases mammary tumorigenesis in rats. Br J Cancer 2004;90:2225-2231. Read the abstract

Horn-Ross PL, Canchola AJ, West DW, Stewart SL, Bernstein L, Deapen D, Pinder R, Ross RK, Anton-Culver H, Peel D, Ziogas A, Reynolds P, Wright W. Patterns of alcohol consumption and breast cancer risk in the California Teachers Study cohort. Cancer Epidemiol Biomarkers Prev 2004;13(3):405-411. Read the abstract

Hussien MM, McNulty H, Armstrong N, Johnston PG, Spence RA, Barnett Y. Investigation of systemic folate status, impact of alcohol intake, and levels of DNA damage in mononuclear cells of breast cancer patients. Br J Cancer 2005;92:1524-1530. Read the abstract

Juarbe TC, Kaplan CP, Somkin CP, Pasick R, Gildengorin G, Perez-Stable EJ. Are risk factors for breast cancer associated with follow-up procedures in diverse women with abnormal mammobraphy? Cancer Casuses Control 2005;16:245-253. Read the abstract

Kim SU, Lee KM, Park SK, Yoo KY, Noh DY, Choe KJ, Ahn SH, Hirvonen A, Kang D. Genetic polymoprhism of glutathione S-transferase P1 and breast cancer risk. J Biochem Mol Biol 2004;37:582-585. Read the abstract

Kuhl H. Breast cancer risk in the WHI study: the problem of obesity. Maturitas 2005;51:83-97. Read the abstract

Kumar NB, Riccardi D, Cantor A, Dalton K, Allen K. A case-control study evaluating the association of purposeful physical activity, body fat distribution, and steroid hormones on premenopausal breast cancer risk. Breast J 2005;11:266-272. Read the abstract

Laufer EM, Hartman TJ, Baer DJ, Gunter EW, Dorgan JF, Campbell WS, Clevidence BA, Brown ED, Albanes D, Judd JT, Taylor PR. Effects of moderate alcohol consumption on folate and vitamin B(12) status in postmenopausal women. Eur J Clin Nutr 2004;58:1518-1524. Read the abstract

Lavigne JA, Wimbrow HH, Clevidence BA, Albert PS, Reichman ME, Campbell WS, Barrett JC, Hursting SD, Judd JT, Taylor PR. Effects of alcohol and menstrual cycle on insulin-like growth factor-1 and insulin-like growth factor binding protein-3. Cancer Epidemiol Biomarkers Prev 2004;13:2264-2267. Read the abstract

Le Marchand L, Haiman CA, Wilkens LR, Kolonel LN, Henderson BE. MTHFR polymorphisms, diet, HRT, and breast cancer risk: the Multiethnic Cohort Study. Cancer Epidemiol Biomarkers Prev 2004;13:2071-2077. Read the abstract

Lilla C, Koehler T, Kropp S, Wang-Gohrke S, Chang-Claude J. Alcohol dehydrogenase 1B (ADH1B) genotype, alcohol consumption and breast cancer risk by a case-control study. Br J Cancer 2005;92:2039-2041. Read the abstract

Lin Y, Kikuchi S, Tamakoshi K, Wakai K, Kondo T, Niwa Y, Yatsuya H, Nishio K, Suzuki S, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A. Prospective study of alcohol consumption and breast cancer risk in Japanese women. Int J Cancer 2005;116:779-783. Read the abstract

Mahabir S, Baer DJ, Johnson LL, Frenkel K, Dorgan JF, Cambell W, Hartman TJ, Clevidence B, Albanes D, Judd JT, Taylor PR. No association between alcohol supplementation and autoantibodies to DNA damange in postmenopausal women in a controlled feeding study. Eur J Cancer Prev 2005;14:427-429. Read the abstract

Madlensky L, Flatt SW, Bardwell WA, Rock CL, Pierce JP, for the WHEL Study group. Is family history related to preventive health behaviors and medical management in breaset cancer patients? Breast Cancer Res Treat 2005;90:47-54. Read the abstract

Madlensky L, Vierkant RA, Vachon CM, Pankratz VS, Cerhan JR, Vadaparampil ST, Sellers TA. Preventive health behaviors and familial breast cancer. Cancer Epidemiol Biomarkers Prev 2005;14:2340-2345. Read the abstract

Mattisson I, Wirfalt E, Wallstrom P, Gullberg B, Olsson H, Berglund G. High fat and alcohol intakes are risk factors of postmenopausal breast cancer: a prospective study from the Malmo diet and cancer cohort. Int J Cancer 2004;110(4):589-597. Read the abstract

McDonald JA, Mandel MG, Marchbanks PA, Folger SG, Daling JR, Ursin G, Simon MS, Bernstein L, Strom BL, Norman SA, Malone KE, Weiss LK, Burkman RT, Weber AL, Spirtas R. Alcohol exposure and breast cancer: results of the Women's Contraceptive and Reproductive Experiences Study. Cancer Epidemiol Biomarkers Prev 2004;13:2106-2116. Read the abstract

Munnia A, Amasio ME, Peluso M. Exocyclic malondialdehyde and aromatic DNA adducts in larynx tissues. Free Rad Biol Med 2004;37(6):850-858. Read the abstract

Muti P. The role of endogenous hormones in the etiology and prevention of breast cancer: the epidemiological evidence. Ann NY Acad Sci 2004;1028:273-282. Read the abstract

Muti P. The role of endogenous hormones in the etiology and prevention of breast cancer: the epidemiological evidence. Recent Results Cancer Res 2005;166:245-256. Review. Read the abstract

Nichols HB, Trentham-Dietz A, Love RR, Hampton JM, Hoang Anh PT, Allred DC, Mohsin SK, Newcomb PA. Differences in breast cancer risk factors by tumor marker subtypes among premenopausal Vietnamese and Chinese women. Cancer Epidemiol Biomarkers Prev 2005;14:41-47. Read the abstract

Onland-Moret NC, Peeters PH, van der Schouw YT, Grobbee DE, van Gils CH. Alcohol and endogenous sex steroid levels in postmenopausal women: a cross-sectional study. J Clin Endocrinol Metab 2005;90:1414-1419. Read the abstract

Petri AL, Tjonneland A, Gamborg M, Johansen D, Hoidrup S, Sorensen TI, Gronbaek M. Alcohol intake, type of beverage, and risk of breast cancer pre- and postmenopausal women. Alcohol Clin Exp Res 2004;28:1084-1090. Read the abstract

Poschl G, Seitz HK. Alcohol and cancer. Alcohol Alcohol 2004;39(3):155-165. Read the abstract

Robert SA, Strombom I, Trentham-Dietz A, Hampton JM, McElroy JA, Newcomb PA, Remington PL. Socioeconomic risk factors for breast cancer: distinguishing individual- and community-level effects. Epidemiology 2004;15:442-450. Read the abstract

Rusiecki JA, Holford TR, Zahm SH, Zheng T. Breast cancer risk factors according to joint estrogen receptor and progesterone receptor status. Cancer Detect Prev 2005;29:419-426. Read the abstract

Singletary KW, Barnes SL, van Breemen RB. Ethanol inhibits benzo[a]pyrene-DNA adduct removal and increases 8-oxo-deoxyguanosine formation in human mammary epithelial cells. Cancer Lett 2004;203(2):139-144. Read the abstract

Tamimi RM, Byrne C, Baer HJ, Rosner B, Schnitt SJ, Connolly JL, Colditz GA. Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case-control study. Breast Cancer Res 2005;7:R555-562. Read the abstract

Terry MB, Zhang FF, Kabat G, Britton JA, Teitelbaum SL, Neugut AI, Gammon MD. Lifetime alcohol intake and breast cancer risk. Ann Epidemiol 2005;Oct 13 [Epub ahead of print]. Read the abstract

Tjonneland A, Christensen J, Thomsen BL, Olsen A, Stripp C, Overvad K, Olsen JH. Lifetime alcohol consumption and postmenopausal breast cancer rate in Denmark: a prospective cohort study. J Nutr 2004;134(1):173-178. Read the abstract

Tjonneland A, Christensen J, Olsen A, Stripp C, Nissen SB, Overvad K, Thomsen BL. Folate intake, alcohol and risk of breast cancer among postmenopausal women in Denmark. Eur J Clin Nutr 2005;Oct 19 [Epub ahead of print]. Read the abstract

Vachon CM, Sellers TA, Janney CA, Brandt KR, Carlson EE, Pankratz VS, Wu FF, Therneau TM, Cerhan JR. Alcohol intake in adolescence and mammographic density. Int J Cancer 2005;Jun 24 [Epub ahead of print]. Read the abstract

Additional published studies

Caleffi M, Teague MW, Jensen RA, Vnencak-Jones CL, Dupont WD, Oarl FF. p53 gene mutations and steroid receptor status in breast cancer. Clinicopathologic correlations and prognostic assessment. Cancer 1994;73:2147-2156. Read the abstract

Ellison RC, Zhang YQ, McLennan CE, Rothman KJ. Exploring the relation of alcohol consumption to risk of breast cancer. American Journal of Epidemiology 2001;154(8):740-747. Read the abstract

Garfinkel L, Boffeta P, Stellman SD. Alcohol and breast cancer: a cohort study. Prev Med 1988;17:686-693.

Harvey EB, Schairer C, Brinton LA, Hoover RN, Fraumeni JF, Jr. Alcohol consumption and breast cancer. J Natl Cancer Inst 1987;78(4):657-661. Read the abstract

Howe G, Rohan T, Decarli A, Iscovich J, Kaldor J, Katsouyanni K, Marubini E, Miller A, Riboli E, Toniolo P. The association between alcohol and breast cancer risk: evidence from the combined analysis of six dietary case-control studies. Int J Cancer 1991;47(5):707-710. Read the abstract

Howe GR, Hirohata T, Hislop TG, Iscovich JM, Yuan JM, Katsouyanni K, Lubin F, Marubini E, Modan B, Rohan T. Dietary factors and risk of breast cancer: combined analysis of 12 case- control studies. J Natl Cancer Inst 1990;82(7):561-569.

Lavigne JA, Wimbrow HH, Clevidence BA, Albert PS, Reichman ME, Campbell WS, Barrett JC, Hursting SD, Judd JT, Taylor PR. Effects of alcohol and mustrual cycle on insulin-like growth factor-I and insulin-like growth factor binding protein-3. Cancer Epidemiol Biomarkers Prev 2004;13:2264-2267.

Longnecker MP, Newcomb PA, Mittendorf R, Greenberg ER, Clapp RW, Bogdan GF, Baron J, MacMahon B, Willett WC. Risk of breast cancer in relation to lifetime alcohol consumption. J Natl Cancer Inst 1995;87:923-929. Read the abstract

Longnecker MP. Alcoholic beverage consumption in relation to risk of breast cancer: meta-analysis and review. Cancer Causes Control 1994;5(1):73-82. Read the abstract

Le Marchand L, Haiman CA, Wilkens LR, Kolonel LN, Henderson BE. MTHFR polymorphisms, diet, HRT, and breast cance rrisk: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 2004;13:2071-2077.

McDonald JA, Mandel MG, Marchbanks PA, Folger SG, Daling JR, Ursin G, Simon MS, Bernstein L, Strom BL, Norman SA, Malone KE, Weiss LK, Burkman RT, Weber AL, Spirtas R. Alcohol exposure and breast cancer: results of the women's contraceptive and reproductive experiences study. Cancer Epidemiol Biomarkers Prev 2004;13:2106-2116.

Moormeier J. Breast cancer in black women. Ann Intern Med 1996;124:897-905. Read the abstract

O'Connell DL, Hulka BS, Chambless LE, Wilkinson WE, Deubner DC. Cigarette smoking, alcohol consumption, and breast cancer risk. J Natl Cancer Inst 1987;78(2):229-234. Read the abstract

Shiao YH, Chen VW, Scheer WD, Wu XC, Correa P. Racial disparity in the association of p53 gene alterations with breast cancer survival. Cancer Res 1995;55:1485-1490. Read the abstract

Singletary K, Nelshoppen J, Wallig M. Enhancement by chronic ethanol intake of N-methyl-N-nitrosourea-induced rat mammary tumorigenesis. Carcinogenesis 1995;16(4):959-964.

Singletary KW, Gapstur SM. Alcohol and breast cancer—Review of epidemiologic and experimental evidence and potential mechanisms. JAMA 2001;286(17):2143-2151. Read the abstract

Singletary KW, McNary MQ, Odoms AM, Nelshoppen J, Wallig MA. Ethanol consumption and DMBA-induced mammary carcinogenesis in rats. Nutr Cancer 1991;16(1):13-23.

Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, Graham S, Holmberg L, Howe GR, Marshall JR, Miller AB, Potter JD, Speizer FE, Willett WC, Wolk A, Hunter DJ. Alcohol and breast cancer in women: a pooled analysis of cohort studies. JAMA 1998; 279(7):535-540. Read the abstract

Tseng M, Weinberg CR, Umbach DM, Longnecker MP. Calculation of population attributable risk for alcohol and breast cancer (United States). Cancer Causes Control 1999;10(2):119-123.

Vachon CM, Cerhan JR, Vierkant RA, Sellers TA. Investigation of an interaction of alcohol intake and family history on breast cancer risk in the Minnesota breast cancer family study. Cancer 2001;92(2):240-248.

Watabiki T, Okii Y, Tokiyasu T, Yoshimura S, Yoshida M, Akane A, Shikata N, Tsubura A. Long-term ethanol consumption in ICR mice causes mammary tumor in females and liver fibrosis in males. Alcohol Clin Exp Res 2000;24(4 Suppl):117S-122S.

Willett WC, Stampfer MJ, Coldlitz GA, Bosner BA, Hennekens CH, Speizer FE. Moderate alcohol consumption and the risk of breast cancer. N Engl J Med 1987;316:1174-1180.

Xuan J, Wang Y, Freedman MT, Adali T, Shields PG. Nonrigid medical image registration by finite-element deformable sheet-curve models. J Biomedical Engineering In Press.