Lucile L Adams-Campbell
Professor and Associate Director, Health Disparities Research
Community health research, interventions, outreach and prevention in high risk populations.
Role of oncogenes, tumor suppressor proteins and cyclin D1 in theinitiation and progression of prostate and breast cancers.
Maria Laura Avantaggiati
Role of the p53 tumor suppressor and of deacetylases in metabolic pathways that confer cancer protection.
Associate Professor and Director, Georgetown University Drug Discovery Program
Anti-cancer drug discovery and the role of voltage gated sodium channels in the etiology and progression of prostate cancer.
Professor and Associate Director for Shared Resources
Gene environment interactions focused on vitamins A and D and wnt signaling in breast and colorectal cancer.
Mechanisms of chemical carcinogenesis with an emphasis on the DNA damage caused by environmental and endogenous chemicals.
Professor and Dean for Graduate Research
Studies hormones (endogenous and exogenous) and related factors affect breast cancer, and how breast cancers become resistant to endocrine and cytotoxic chemotherapies.
Chair and Professor of Biochemistry and Molecular Biology
Control of chromosomal replication; role ofpolyphosphates in cellular responses to environmental stresses.
Oncogenic and genotoxic stress signaling, including application of systems biology approaches to stress signaling in cancer.
Priscilla A Furth
Cancer progression and regression, hormonal signaling pathways and cell survival and differentiation.
Robert I Glazer
PDK1 in mammary epithelial cell transformation and metastasis; PPAR-gamma in chemoprevention and stem cell self-renewal.
Radoslav (Rado) Goldman
Studies of progression of chronic hepatitis viral infection tohepatocellular carcinoma, identification of markers for earlydetection of cancer.
Leena A Hilakivi-Clarke
Fetal, pubertal and pregnancy dietary exposures to different types of fats, plant-derived bioactive components and alcohol, and risk of breast and other endocrine cancers.
Professor and Research Director, CW Bill Young Marrow Donor Recruitment and Research Program
Role of genetic diversity in human immune response with focus on hematopoietic stem cell transplantation
Michael D Johnson
Role of proteases in the invasion, progression and metastasis of breast cancer.
V. Craig Jordan
Vice Chairman, Department of Oncology
Drug discovery for breast cancer treatment and prevention
Usha N Kasid
Raf-1/Erk signaling; new molecular targets; tumor growth, metastasis, and radiation resistance; antisense and siRNA; liposomal delivery systems; breast, prostate, and pancreatic cancer.
Professor and Coleader of Cancer Prevention and Control Program
Role of infectious diseases, environmental exposures, and genetic susceptibility to cancers of childhood and adulthood.
Mary Beth Martin
Role of estrogen and the estrogen receptor in etiology and progression of breast cancer.
Proessor and Coleader of Molecular Oncology Program
Role of oncogenes in mechanisms of human carcinogenesis and the cellular stress response, with emphasis on molecular targets and pathways for chemo- and radiosensitization.
Anna Tate Riegel
Professor and Director for Cancer Research Education
Mechanisms of cross talk between hormone and growth factor signaling in human breast and pancreatic cancer.
Cellular and molecular mechanisms of hormone independence and therapeutic resistance in breast cancer.
Eliot M Rosen
Role of the breast cancer susceptibility gene (BRCA1) in signaling and prevention in breast, prostate and brain cancer.
Role of Repair mechanisms of Oxidative and Alkylation DNA damage inmutations, cancer and chemoprevention.
C. Richard Schlegel
Academic Chairand Professor of Pathology
Molecular and immunological studies of the human papillomaviruses and their role in neoplasia.
Jeffery A Toretsky
Profesor and Coleader of Molecular Oncology Program
Development of novel childhood cancer therapeutics using chemical genomics
Role of Wnt/beta-catenin signaling in cancer pathogenesis.
Todd A Waldman
Functional analysis of the PTEN tumor suppressor gene and genetic analysis of glioblastoma pathogenesis.
Louis M Weiner
Director, Georgetown Lombardi Comprehensive Cancer Center
Therapeutic approaches to fight cancer using monoclonal antibodies
Professor and Associate Director for Basic Science
The role of growth factors in the cancer cell / stroma interaction.
Dissection of the signaling crosstalk between cancer pathways using a combination of in vitro and in vivo approaches.