Senior Team Members


Robert Clarke, PhD, DSc (PI): An internationally recognized leader in breast cancer research, Clarke studies how hormones, growth factors, and other related molecules affect breast cancer, and how breast cancers become resistant to hormonal and cytotoxic chemotherapies. He has expertise in the fields of estrogens, antiestrogens, aromatase inhibitors, cell signaling, drug resistance, bioinformatics, and signal transduction. Read more


William T. Baumann, PhD: associate professor at Virginia Tech, Baumann's recent work has been in the field of systems biology, which attempts to apply a systems approach to modeling and understanding biological systems. One of his projects involves stochastic modeling of the yeast cell cycle to produce a more accurate model of this important system as well as to understand the impact of molecular noise on cell cycle progression. Read more


Milton Brown, MD, PhD: director of Drug Dicovery at Georgetown Lombardi Comprehensive Center. In addition to his research and academic responsibilities at GUMC, Dr. Milton Brown has established the Drug Discovery Program (DDP) at the Georgetown University Medical Center, which supports more than 20 investigators in drug discovery and development. Read more


Erica A. Golemis, PhD: tenured professor, Co-Leader of the Developmental Therapeutics Program, and Co-Director of the Keystone Initiative in Head and Neck Cancer at Fox Chase Cancer Center. Dr. Golemis’ group studies complex signaling interactions in cancer. One major lab effort is investigation of the HEF1/NEDD9 metastasis scaffolding protein.


Leena A. Hilakivi-Clarke, PhD: professor of Oncology, Hilakivi-Clarke's research interests include molecular pathways (estrogen receptor, oxidative damage, and tumor suppressors BRCA1, p53 and caveolin), mediating the effects of timing (in utero, childhood, pregnancy) of dietary exposures (fatty acids, phytochemicals, and obesity) on breast cancer risk. Read more


Minetta C. Liu, MD: assistant professor of Medicine and Oncology at GUMC. Liu joined the faculty of the Breast Cancer Program in July 2001. Liu is heavily involved in translational research with a focus on the use of microarray gene analysis in identifying the molecular mechanisms responsible for determining chemotherapy sensitivity versus resistance. Read more


Subha Madhavan, PhD: director of Clinical research informatics at the Lombardi comprehensive cancer center at Georgetown University. She is an information scientist who has worked in the field of biomedical informatics and clinical data management and analysis for the past 11 years. Prior to joining Georgetown Dr. Madhavan served as the Associate Director of Product and Program Management in the Life sciences informatics area at NCI's Center for Biomedical Informatics and Information technology (CBIIT) where she led the development of several bioinformatics programs including the Cancer Genome Atlas (TCGA) project and the platform supporting the REMBRANDT project, which received the Service to America Medal in 2005. Her work at NCI involved bridging the gap between bench and bedside by enabling researchers and physician scientists to use cutting edge biomedical informatics solutions to identify better therapies for cancer. Read more


John J. Tyson, PhD: faculty fellow, Virginia Bioinformatics Institute. Tyson is a computational cell biologist, interested at present in the molecular mechanisms underlying the control of cell growth, division and death. Earlier he worked on oscillations and wave propagation in chemical reaction systems. Read more


Jianhua Xuan, PhD: associate professor of Computational Bioinformatics and Bioimaging at Virginia Tech. Read more


Yue Wang, PhD: Grant A. Dove professor of Computational Bioinformatics and Bioimaging at Virginia Tech. Read more


Louis Weiner, MD: An internationally recognized medical oncologist specializing in the treatment in gastrointestinal cancers, Weiner is also an accomplished researcher developing novel immunotherapy treatments in his laboratory. Named director of the Lombardi Comprehensive Cancer Center in 2007, Weiner is recognized for his laboratory and clinical research focusing on new therapeutic approaches that mobilize the patient’s immune system to fight cancer using monoclonal antibodies - laboratory-crafted proteins designed to recognize specific cancer cells. Read more